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Interferon lambda protects the female reproductive tract against Zika virus infection [PDF]
Zika virus infections can cause devastating congenital birth defects but the underlying interactions with the host immune system are not well understood.
Arora, Nitin+7 more
core +3 more sources
Congenital Zika virus syndrome consists of a large spectrum of neurologic abnormalities seen in infants infected with Zika virus in utero. However, little is known about the effects of Zika virus intrauterine infection on the neurocognitive development ...
Lorenzo Subissi+17 more
doaj +1 more source
The Brazilian Zika virus strain causes birth defects in experimental models
Zika virus infection has been linked to an increase in the number of infants born with microcephaly in Brazil, but direct experimental proof that Zika virus causes birth defects was lacking. Here Alysson Muotri and colleagues show that the Brazilian Zika
Fernanda R. Cugola+25 more
semanticscholar +1 more source
Whole-Blood Testing for Diagnosis of Acute Zika Virus Infections in Routine Diagnostic Setting
We evaluated the benefit of whole blood versus plasma to detect acute Zika virus infections. Comparison of Zika virus quantitative reverse transcription PCR results in single timepoint whole blood–plasma pairs from 227 patients with suspected Zika virus ...
Jolanda J.C. Voermans+6 more
doaj +1 more source
Examining Zika Virus: Transmission, Diagnosis, Treatment, and Prevention [PDF]
The Zika virus is a mosquito-borne virus that was first isolated in Uganda in 1947 and has since caused outbreaks in many parts of the world. It has multiple routes of transmission and may cause acute illness and death if not treated.
Taybeh, Noura
core +1 more source
Zika virus infection in semen: Effect on human reproduction [PDF]
Unique among vector-borne flaviviruses, Zika virus can infect testis and male genital tract, can persist in semen for months after symptoms onset, and be sexually transmitted.
Barzon, Luisa+2 more
core +1 more source
Zika Virus Outbreak, Bahia, Brazil
To the Editor: Zika virus (ZIKV) is a mosquito-borne flavivirus related to yellow fever virus, dengue virus (DENV), and West Nile virus (WNV). It is a single-stranded positive RNA virus (10,794-nt genome) that is closely related to the Spondweni virus ...
G. Campos, A. Bandeira, S. Sardi
semanticscholar +1 more source
Infectious causes of microcephaly: epidemiology, pathogenesis, diagnosis, and management. [PDF]
Microcephaly is an important sign of neurological malformation and a predictor of future disability. The 2015-16 outbreak of Zika virus and congenital Zika infection brought the world's attention to links between Zika infection and microcephaly. However,
Abdel Razek+147 more
core +2 more sources
Transmission of Zika virus by dendritic cell subsets in skin and vaginal mucosa
Zika virus is a member of the Flaviviridae family that has caused recent outbreaks associated with neurological malformations. Transmission of Zika virus occurs primarily via mosquito bite but also via sexual contact. Dendritic cells (DCs) and Langerhans
Julia Eder+8 more
doaj +1 more source
Zika Virus and Global Health Security [PDF]
Americans are largely apathetic about the risks of Zika virus and Congress cannot agree on preparedness funding. Strategies to counter the spread of Zika by the World Health Organisation (WHO) grossly underestimate the disease’s impact.
Gostin, Lawrence O.+1 more
core +3 more sources