Scientific Reports, 2022 Zonula occludens (ZO)-1, a tight-junction protein (TJP), is expressed in dendritic cells (DCs) but not in monocytes, and 27-hydroxycholesterol (27OHChol) drives the differentiation of monocytes into DCs.
Hyok-rae Cho +5 more
doaj +1 more source
PIK3R3 regulates ZO-1 expression through the NF-kB pathway in inflammatory bowel disease.
International Immunopharmacology, 2020 BACKGROUND AND AIMS Inflammatory bowel disease (IBD) are the major risk factor for developing colitis associated cancer (CAC). Previously, we have reported that Phosphoinositide-3-kinase regulatory subunit 3 (PIK3R3) was overexpressed in colorectal ...
Sidikjan Ibrahim +4 more
semanticscholar +1 more source
Iranian Journal of Microbiology, 2019 Background and Objectives: Although zinc oxide (ZO)-calcium hydroxide (CaOH) mixtures have been successful regarding their absorption rate compatibility with dissolving primary teeth, no study has been conducted on the appropriate mixture ratio to obtain
Ali Nozari +3 more
doaj +1 more source
Neuronal connexin36 association with zonula occludens‐1 protein (ZO‐1) in mouse brain and interaction with the first PDZ domain of ZO‐1 [PDF]
European Journal of Neuroscience, 2004 AbstractAmong the 20 members in the connexin family of gap junction proteins, only connexin36 (Cx36) is firmly established to be expressed in neurons and to form electrical synapses at widely distributed interneuronal gap junctions in mammalian brain.
Xinbo, Li +6 more
openaire +2 more sources
Barrier-protective effects of activated protein C in human alveolar epithelial cells [PDF]
, 2014 Acute lung injury (ALI) is a clinical manifestation of respiratory failure, caused by lung inflammation and the disruption of the alveolar-capillary barrier.
Adda, Mélania +6 more
core +2 more sources
Multiple effects of angiostatins in injured cornea [PDF]
The Ukrainian Biochemical JournalProlonged inflammation and excessive neovascularization of the cornea due to severe injury can impair optical clarity and lead to vision impairment. Plasminogen kringle (K) fragments, known as angiostatins (AS), play a well-established role as inhibitors
V. L. Bilous, A. O. Tykhomyrov
doaj +1 more source
Cell Reports, 2020 Summary Tight-junction-regulated actomyosin activity determines epithelial and endothelial tension on adherens junctions and drives morphogenetic processes; however, whether or not tight junctions themselves are under tensile stress is not clear.
Alexis J. Haas +7 more
semanticscholar +1 more source
Redifferentiation and ZO‐1 reexpression in liver‐metastasized colorectal cancer: Possible association with epidermal growth factor receptor‐induced tyrosine phosphorylation of ZO‐1 [PDF]
Cancer Science, 2003 Tubular gland structures of colorectal cancer (CRC) have been demonstrated to undergo dedifferentiation at the primary site, and then the gland structures are re‐formed in the liver me‐tastases. In this study, we examined the degree of differentiation of the gland structure of 48 cases of CRCs (24 cases with synchronous liver metastasis, 24 cases ...
Tsukasa, Kaihara +8 more
openaire +2 more sources
Longitudinal Changes to Tight Junction Expression and Endothelial Cell Integrity in a Mouse Model of Sterile Corneal Inflammation [PDF]
, 2016 PURPOSE: We previously reported that applying toll-like receptor (TLR) ligands to an injured cornea induces corneal edema at 24 hours, which subsides by 1 week.
Larkin, DFP
core +1 more source
Allosteric Activation of the Par-6 PDZ Via a Partial Unfolding Transition [PDF]
, 2013 Proteins exist in a delicate balance between the native and unfolded states, where thermodynamic stability may be sacrificed to attain the flexibility required for efficient catalysis, binding, or allosteric control.
Kovrigin, Evgeni L. +3 more
core +2 more sources