Results 61 to 70 of about 27,376,677 (317)
Localization of ZO-1 in the Nucleolus of Corneal Fibroblasts
Investigative Opthalmology & Visual Science, 2007 Within the multidomain structure of ZO-1 are motifs responsible for ZO-1's localization to intercellular junctions and its newly demonstrated localization to the leading edge of lamellipodia in corneal fibroblasts. Since ZO-1 also has two nuclear localization signals, this study was undertaken to determine whether stimuli associated with wounding would
Miriam, Benezra +2 more
openaire +2 more sources
PSD-95 Is Associated with the Postsynaptic Density and Not with the Presynaptic Membrane at Forebrain Synapses [PDF]
, 1996 PSD-95, a prominent protein component of the postsynaptic density (PSD) fraction from rat forebrain, has been localized by light microscopy to dendrites of hippocampal neurons (Cho et al., 1992) and to the presynaptic plexus of cerebellar basket cells ...
Hunt, Carol A. +2 more
core +1 more source
ZO-1: Lamellipodial Localization in a Corneal Fibroblast Wound Model
Investigative Opthalmology & Visual Science, 2005 To explore the roles of ZO-1 in corneal fibroblasts and myofibroblasts in a model of wounding.Antibodies were used to identify ZO-1 in cultured rabbit corneal fibroblasts by immunocytochemistry, Western blot analysis, and immunoprecipitation. For colocalization studies, antibodies to beta-catenin, cadherins, connexins, integrins, alpha-actinin, and ...
Lavinia, Taliana +4 more
openaire +2 more sources
Developmental expression of claudins in the mammary gland [PDF]
, 2017 Claudins are a large family of membrane proteins whose classic function is to regulate the permeability of tight junctions in epithelia. They are tetraspanins, with four alpha-helices crossing the membrane, two extracellular loops, a short cytoplasmic N ...
Baumgartner, Heidi K. +8 more
core +1 more source
Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin [PDF]
, 2020 Streptococcus pneumoniae serotype 1 is the predominant cause of invasive pneumococcal disease in sub-Saharan Africa, but the mechanism behind its increased invasiveness is not well understood.
Baltazar, Murielle +11 more
core +4 more sources
ZO-1 and ZO-2 are required for extra-embryonic endoderm integrity, primitive ectoderm survival and normal cavitation in embryoid bodies derived from mouse embryonic stem cells. [PDF]
PLoS ONE, 2014 The Zonula Occludens proteins ZO-1 and ZO-2 are cell-cell junction-associated adaptor proteins that are essential for the structural and regulatory functions of tight junctions in epithelial cells and their absence leads to early embryonic lethality in ...
Dominic C Y Phua +5 more
doaj +1 more source
Royal Society Open Science, 2023 Nano-zirconia (ZO) was synthesized using a microwave-assisted one-pot precipitation route. Two biopolymers, chitosan (CTS) and carboxymethyl cellulose were blended with ZO at different w/w ratios.
M. Shanika Fernando +7 more
doaj +1 more source
Tight junction protein ZO-1 in Kawasaki disease
, 2020 Abstract BackgroundKawasaki disease (KD) is a form of systemic febrile vasculitis that can be complicated by coronary artery lesions (CAL). A murine model of KD vasculitis showed that the vasculitis depended on intestinal barrier dysfunction, as well as that the tight junctions maintain the intestinal barrier.
Wan-Tz Lai +3 more
openaire +1 more source
ZO-1 is involved in trophoblastic cell differentiation in human placenta [PDF]
American Journal of Physiology-Cell Physiology, 2010 Trophoblastic cell-cell fusion is an essential event required during human placental development. Several membrane proteins have been described to be directly involved in this process, including connexin 43 (Cx43), syncytin 1 (Herv-W env), and syncytin 2 (Herv-FRD env glycoprotein).
Pidoux, Guillaume +10 more
openaire +2 more sources
MicroRNA‑103 regulates tumorigenesis in colorectal cancer by targeting ZO‑1
Molecular Medicine Reports, 2017 Given the emerging role of microRNAs (miRs) in cancer progression, the present study investigated the role and underlying mechanism of miR‑103 in colorectal cancer (CRC). Reverse transcription‑quantitative polymerase chain reaction was conducted to quantify the expression levels of miR‑103 in clinical specimens and cell lines.
Ke, Jin +5 more
openaire +3 more sources