Results 71 to 80 of about 27,376,677 (317)
Chronic inflammatory demyelinating polyneuropathy: decreased claudin-5 and relocated ZO-1 [PDF]
To clarify the dynamics of molecules composing the blood-nerve barrier (BNB) in inflammatory neuropathies.The expression of four tight junction (TJ) proteins-claudin-1, claudin-5, occludin, and ZO-1-was analysed immunohistochemically in sural nerve biopsy specimens obtained from patients with chronic inflammatory demyelinating polyradiculoneuropathy ...
T, Kanda, Y, Numata, H, Mizusawa
openaire +2 more sources
Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus [PDF]
Synaptic NMDA-type glutamate receptors are anchored to the second of three PDZ (PSD-95/Discs large/ZO-1) domains in the postsynaptic density (PSD) protein PSD-95.
Apperson, Michelle +3 more
core +1 more source
Expression pattern of E-Cad, Ocln and ZO-1 in cleavage-stage Monodelphis domestica embryos [PDF]
Digitalitzat per ...
Wang, Vicki N., Cruz, Yolanda P.
core +1 more source
Carcinoma in situ (CIS) is the noninvasive precursor of most human testicular germ cell tumors. In normal seminiferous epithelium, specialized tight junctions between Sertoli cells constitute the major component of the blood-testis barrier. Sertoli cells
Cornelia Fink +6 more
doaj +1 more source
Intestinal epithelial cell tight junctions (TJs) contribute to the integrity of the intestinal barrier allowing for control of the physical barrier between external antigens or bacterial products and the internal environment. Zonula occludens-1 (ZO-1) is
Namita Power +10 more
doaj +1 more source
Neuregulin-1 attenuates experimental cerebral malaria (ECM) pathogenesis by regulating ErbB4/AKT/STAT3 signaling. [PDF]
BACKGROUND:Human cerebral malaria (HCM) is a severe form of malaria characterized by sequestration of infected erythrocytes (IRBCs) in brain microvessels, increased levels of circulating free heme and pro-inflammatory cytokines and chemokines, brain ...
Cespedes, Juan Carlos +5 more
core +1 more source
An understanding of the quantitative relationship between bile canaliculus (BC) dynamics and the disruption of tight junctions (TJs) during drug‐induced intrahepatic cholestasis may lead to new strategies aimed at drug development and toxicity testing ...
Rie Sonoi, Yoshihisa Hagihara
doaj +1 more source
Zonula occludens 2 and Cell-Cell Contacts Are Required for Normal Nuclear Shape in Epithelia
MAGUK protein ZO-2 is present at tight junctions (TJs) and nuclei. In MDCK ZO-2 knockdown (KD) cells, nuclei exhibit an irregular shape with lobules and indentations.
Christian Hernández-Guzmán +4 more
doaj +1 more source
Visualizing the dynamic coupling of claudin strands to the actin cytoskeleton through ZO-1
GFP claudins (cldns) make dynamic strand patches between fibroblasts regulated by ZO-1 binding. Independent of ZO-1, cldn strands break and reanneal; new cldns are preferentially incorporated into break sites.
C. V. Van Itallie +2 more
semanticscholar +1 more source
The Unique-5 and -6 Motifs of ZO-1 Regulate Tight Junction Strand Localization and Scaffolding Properties [PDF]
The proper cellular location and sealing of tight junctions is assumed to depend on scaffolding properties of ZO-1, a member of the MAGUK protein family. ZO-1 contains a conserved SH3-GUK module that is separated by a variable region (unique-5), which in
Anderson, James M. +5 more
core

