Results 81 to 90 of about 29,804,163 (234)
, 2013 ZO-1 expression was evaluated using flow cytometry after incubation with HMW-HA or MMW-HA or LMW-HA at 0.2% for 24 hours. Results showed a strong increase in ZO-1 expression after MMW-HA incubation. A: cell culture medium, B: HMW-HA, C: MMW-HA, D: LMW-HA
Jean-Michel Warnet (298323) +3 more
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Cingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3, and myosin [PDF]
, 1999 We characterized the sequence and protein interactions of cingulin, an M(r) 140-160-kD phosphoprotein localized on the cytoplasmic surface of epithelial tight junctions (TJ).
Shore, David M. +18 more
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Advanced Science, EarlyView.Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin +13 more
wiley +1 more source
, 2018 Endothelial cell VCAM-1 regulates recruitment of lymphocytes, eosinophils, mast cells, or dendritic cells during allergic inflammation. In this report, we demonstrated that, during allergic lung responses, there was reduced zonula occludens (ZO)-1 ...
Michelle E Marchese +3 more
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Advanced Science, EarlyView.This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori +10 more
wiley +1 more source
, 2013 Sections of distal ileum harvested 2 and 6 hours after 55% TBSA burn were labeled for ZO-1 (A-H). A, E and B, F: representative image from sham+NS (A, E) and sham+VPA (B, F) group showing normal intestinal ZO-1 expression; ZO-1 was densely and ...
Zhi-Long Lin (473537) +11 more
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Advanced Science, EarlyView.Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li +23 more
wiley +1 more source
, 2014 Coordinated cell proliferation and ability to form intercellular seals are essential features of epithelial tissue function. Tight junctions (TJs) classically act as paracellular diffusion barriers. More recently, their role in regulating epithelial cell
Feraille, Eric +7 more
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Advanced Science, EarlyView.A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal +5 more
wiley +1 more source
Validation of CTR-ZO-1 interaction.
, 2016 A. FLAG-CTR-C-pull down. The beads containing GST-fusion proteins of C, CTR-Cwt and CTR-C∆ESS (2 μg proteins) were incubated with PC-3 cell lysates for 6 h at 4o C, washed, and bound proteins were eluted with 5 mM reduced glutathione.
Vijaybasker Lakshmikanthan (2548531) +5 more
core +1 more source