Results 101 to 110 of about 8,610 (178)

In silico analysis reveals distinct changes in markers of epithelial to mesenchymal transition in glioma subtypes

Biomolecules & Biomedicine
Epithelial to mesenchymal transition (EMT) plays a critical role in tumor progression and metastasis, including in gliomas. To examine and interpret data on major genes involved in EMT and associate their changes with low-grade (LGG) and/or high-grade ...
Nives Pećina-Šlaus, Alja Zottel, Željko Škripek, Borna Puljko, Fran Dumančić, Anja Bukovac, Ivana Jovčevska, Anja Kafka   +7 more
doaj   +1 more source

3种典型不饱和脂肪酸对Caco-2肠上皮细胞 机械屏障功能的影响Influences of three typical unsaturated fatty acids on mechanical barrier function of Caco-2 intestinal epithelial cells

Zhongguo youzhi
旨在为优化膳食脂肪摄入结构，预防相关慢性代谢类疾病提供一定的理论依据，通过构建Caco-2肠上皮细胞机械屏障模型，考察不同脂肪酸〔油酸（OA）、亚油酸（LA）和α-亚麻酸（ALA）〕对Caco-2细胞模型完整性和通透性的影响，以及对Caco-2细胞机械屏障相关基因及关键蛋白表达水平的调控作用。结果表明：在脂肪酸浓度300 μmol/L、干预时间24 h条件下，LA显著降低跨膜电阻值和碱性磷酸酶比活性，升高表观渗透系数和一氧化氮含量，而OA和ALA对上述指标无显著影响；LA显著下调胞质紧密黏连蛋白1 ...
杜舒梦1，李蕊1，刘元法1,2，杨巍1,2，叶展1,2DU Shumeng1, LI Rui1, LIU Yuanfa1,2, YANG Wei1,2, YE Zhan1,2
doaj  

ELMOD3 is linked to the F-actin cytoskeleton.

, 2013
(A) In transfected MDCK cells, GFP-ELMOD3 (green) localized with F-actin at the cell membrane. Alexa647-phalloidin (blue) was used to stain F-actin, and a ZO1 antibody was used to label the tight junctions (red).
Elodie M. Richard (454396), Thomas J. Jaworek (454395), Saima Riazuddin (454401), Shaheen N. Khan (454400), Sheikh Riazuddin (92774), Anna A. Ivanova (454397), Arnaud P. J. Giese (454398), Daniel I. Choo (454399), Richard A. Kahn (119163)   +8 more
core   +1 more source

Immunohistochemistry of junctional markers on endothelial cells.

, 2014
Localization of ZO1 expression/detection was heterogeneous, with it being only visible as part of the membrane (i.e. cellular junctions) on elongated and arranged endothelial cells (red arrows), but being mostly cytoplasmic in clumped and non-elongated ...
Pierre-Olivier Couraud (104144), Michel Modo (229135), John D. Sinden (626010), Chung-Hsing Chou (626009)   +3 more
core   +1 more source

miRNA-328-3p regulates ZO-1 expression and inhibits PEDV proliferation via the PLC-β1-PKC pathway.

PLoS ONE
Porcine epidemic diarrhea virus (PEDV) is a significant pathogen affecting swine, causing severe economic losses worldwide. This study explores the regulatory role of miRNA-328-3p to ZO-1 expression and its impact on PEDV proliferation via the PLC-β1-PKC
Han Zhao, Jiayu Zhang, Dengliang Li, Zhanding Cui, Jiuyuan Liu, Di Bao, Yiming Wei, Xinyue Zhang, Zhimin Wu, Tianqi Zhang, Kai Wang, Shushuai Yi, Wei Lian, Guixue Hu   +13 more
doaj   +1 more source

MAPK/FoxA2-mediated cigarette smoke-induced squamous metaplasia of bronchial epithelial cells

International Journal of COPD, 2017
Chunling Du,* Jinchang Lu,* Lei Zhou, Bo Wu, Feng Zhou, Liang Gu, Donghui Xu, Yingxin Sun Department of Respiratory Medicine, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China *These authors contributed equally to this work ...
Du C, Lu J, Zhou L, Wu B, Zhou F, Gu L, Xu D, Sun Y   +7 more
doaj  

Generación de constructos marcados fluorescentemente para la mejora de la microscopía en cultivos 2D y 3D

, 2019
Fluorescence microscopy is a very useful tool for biological research as it allows selective molecule labeling and life-cell imaging. In the last decades, the development of super resolution microscopy techniques has enabled us to gain a deeper insight ...
Temporal Plo, África, Kozjak-Pavlovic, Vera   +1 more
core  

Investigation of the Effects of Postbiotics Obtained from <i>Pediococcus acidilactici</i> on Specific Biomarker Expressions in Intestinal Tissue. [PDF]

Foods
Demircioğlu I, Dörtbudak MB, Karaavci FA, Aydemir ME, Demircioğlu M, Genç A, Demircioğlu A, Güngör G, Di Cerbo A.   +8 more
europepmc   +1 more source

Interaction of inflammatory cells with Tight Junction Proteins in Psoriasis

, 2014
Diese Arbeit beschäftigt sich mit dem veränderten Expressionsmuster der Tight Junction-Proteine ZO1, Claudin-1 und Occludin in der Früh- und Spätform der Psoriasis und dem Zusammenhang zwischen diesen Veränderungen und CD4+-, FoxP3+- und CD8+- T-Zellen ...
Eisele, Melanie Sylvia
core  

An epithelial morphogenetic program for maximal urine concentration. [PDF]

Nat Commun
Warshaw JN, Oh S, Chaney CP, Felan BL, Pham JB, Hiremath C, Geshow K, Liu H, Rivera AM, Wong R, Zhang S, Dean KM, Fiolka RP, Dellinger MT, Whittamore JM, Carroll TJ, Marciano DK.   +16 more
europepmc   +1 more source