Results 71 to 80 of about 8,610 (178)

Junction-based lamellipodia drive endothelial cell rearrangements in vivo via a VE-cadherin-F-actin based oscillatory cell-cell interaction [PDF]

open access: yes, 2018
Angiogenesis and vascular remodeling are driven by extensive endothelial cell movements. Here, we present in vivo evidence that endothelial cell movements are associated with oscillating lamellipodia-like structures, which emerge from cell junctions in ...
Hogan, BM   +21 more
core   +3 more sources

Genipin‐Crosslinked, Silane‐Anchored 3D Tumor–Stroma Microtissues for High‐Content On‐Chip Drug Testing

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 24, 25 June 2026.
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach   +4 more
wiley   +1 more source

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

open access: yesAdvanced Science, Volume 13, Issue 36, 29 June 2026.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou   +8 more
wiley   +1 more source

Change of reception and lactate transport by cerebral endothelium under the influence of viral and bacterial inflammation in vitro

open access: yesФундаментальная и клиническая медицина, 2020
Aim. To study the effect of neuroinflammation inducers of viral and bacterial origin on the reception and transport of lactate in endothelial cells of the brain in vitro.Materials and Methods.
E. B. Boytsova   +4 more
doaj   +1 more source

Hepatoprotective Potential of Walnut Oil Unsaponifiable Matter on Aging‐Induced Liver Injury via Gut Microbiota–Liver Axis

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
USM protects against aging‐induced liver injury by modulating the gut‐liver axis. It enriches beneficial microbiota (e.g., Akkermansia and Lactobacillus) and upregulates tight junction proteins (ZO‐1, Occludin, Claudin) to restore the intestinal barrier.
Junjun Zhou   +10 more
wiley   +1 more source

LOCALIZATION OF TIGHT JUNCTIONS BETWEEN TANYCYTE-LIKE CELLS OF THE SULCUS MEDIANUS ORGANUM IN RAT BRAIN

open access: yesThe Iraqi Journal of Medical Sciences, 2017
Background: Tanycytes are highly specialized ependymal cells (ECs) that line the regions of circumventricular organs (CVOs) where the blood-brain barrier is absent.
Fadhil H. Ahmed   +3 more
doaj   +6 more sources

Culture Optimization of the IPEC–J2 Piglet Jejunum Cell Line for Applications in Infant Nutrition Research

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 12, 28 June 2026.
IPEC–J2 cell line is derived from piglet jejunal cells. Four different culture media were assessed for their ability to support IPEC‐J2 differentiation into an in vitro gut barrier. PS10 media proved most successful. Once differentiated with PS10, the IPEC‐J2 barrier was sufficiently robust for treatment with digested infant food. This demonstrates the
Francesca Bietto   +6 more
wiley   +1 more source

AJAP1 Gene Silencing in Epithelial Cells Alters Protein Expression

open access: yes, 2022
Introduction: The epicardial layer of the heart is formed from a transitory structure known as the proepicardium (PE). Proepicardial cells migrate away from the PE and they surround and adhere to the myocardium to form a layer of epithelial cells that ...
Jeffers, Cameron   +3 more
core  

Assessment of Descemet’s Membrane denudation technique.

open access: yes, 2023
(A) Representative stereoscopic microscope images of the DM before (left panel) and after (right panel) the decellularization process. (B) Immunofluorescence showing the expression of tight junction protein ZO1 (left panels; green) and sodium-potassium ...
Francesco Parmeggiani (845625)   +10 more
core   +1 more source

Representative signals of investigated proteins in the ileum of young goats receiving an N and/or Ca reduced diet.

open access: yes, 2016
A: CLDN2; B: CLDN12; C: OCLN; D: ZO1.
Isabell Marr (2633686)   +6 more
core   +1 more source

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