Results 61 to 70 of about 202,233 (299)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Mother-child interaction within the Zone of Proximal Development. Impact of adult educational level and socio-affective proximity on the effectiveness of tutoring. [PDF]

open access: yes, 2017
de póster presentado a VI International Conference “Early Childhood Care and Education”, Lomonosov Moscow State University –MSU (Moscow, Russia), Mayo 2017.Research problem.
Barajas-Esteban, Maria Carmen   +1 more
core  

Arterial dysgenesis and limb defects : Clinical and experimental examples [PDF]

open access: yes, 2017
Acknowledgements This article is dedicated to Dr David S. Packard Jr. With thanks to Dr John DeSesso, Dr Lewis B. Holmes, Dr Mark Levinsohn, Dr David S.
Hootnick, David R., Vargesson, Neil
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Integrating computational thinking into a longitudinal data analysis course for public health students

open access: yesDiscover Education, 2022
After completing an introductory biostatistics course, public health students often need to take one or more follow-on courses focusing on specialized areas of biostatistics.
Qi Zheng
doaj   +1 more source

A Decriptive Overview of Dynamic Assessment

open access: yese-Kafkas Eğitim Araştırmaları Dergisi, 2023
Dynamic assessment (DA), deriving from the Vygotskian Sociocultural theoretical approach, has attracted considerable attention from researchers in the fields of psychology and general education, but it is still regarded as a novel approach within the ...
İsmail Mirici, Yelda Orhon
doaj   +1 more source

Differential Expression Of Gap Junction mRNAs And Proteins In The Developing Murine Kidney And In Experimentally Induced Nephric Mesenchymes [PDF]

open access: yes, 1992
The expression of three gap junction (GJ) proteins, alpha-1 (Cx43), beta-1 (Cx32), and beta-2 (Cx26), and their transcripts were examined during the ontogeny of the mouse and rat kidney. These proteins were expressed in two non-overlapping patterns.
Gilbert, Scott F.   +6 more
core   +1 more source

Tree growth and management in Ugandan agroforestry systems: effects of root pruning on tree growth and crop yield [PDF]

open access: yes, 2008
Tree root pruning is a potential tool for managing below-ground competition when trees and crops are grown together in agroforestry systems. This study investigates its effects on growth and root distribution of Alnus acuminata (HB & K), Casuarina ...
Deans, J. Douglas   +5 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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