Results 61 to 70 of about 167,100,566 (339)
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Infinity, 2020 This study aimed to (1) analyze the role of scaffolding in deconstructing pseudo-thinking structure, and (2) analyze the development of students' thinking structures after receiving scaffolding.
Imam Kusmaryono +2 more
doaj +1 more source
A theoretical exploration: Zone of Proximal Development as an ethical zone for teaching mathematics
Avances de Investigación en Educación Matemática, 2021 For decades, Vygotsky’s Zone of Proximal Development (ZPD) has been utilized as an important theoretical framework for exploring and analysing the concept of learning, but its implications for teachers remain much less explored.
Yasmine Abtahi
doaj +1 more source
Guided reading – Working within a child's zone of proximal development
, 2021 Research has shown that exposing children to rich literacy practices gives children a strong start that will influence lifelong success in learning, wellbeing and participation in civic life.
Maria Nicholas, N. Veresov, J. Clark
semanticscholar +1 more source
La evaluación formativa y la Zona de Desarrollo Proximal [PDF]
, 2019 Este artigo tem por objetivo apresentar as possíveis relações entre a avaliação formativa e a Zona de Desenvolvimento Proximal de Vygotsky. Como método de pesquisa, optou-se por utilizar a pesquisa especulativa, pois a intenção é produzir um texto ...
Rossetto, Hallynnee Héllenn Pires +2 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A Goldilocks approach to transdisciplinary learning
Journal of the European Honors CouncilIn today’s world, education is increasingly being called upon to do more. Beyond transmitting knowledge, we need to cultivate both capability and agency in learners to navigate the complexity and uncertainty of our time.
Jan-Peter Sandler
doaj +3 more sources
Development Effectiveness Overview (DEO) 2020: Executive Summary
, 2020 The Development Effectiveness Overview (DEO) is an annual report produced by the IDB Group to share the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source