Results 61 to 70 of about 202,233 (299)
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Mother-child interaction within the Zone of Proximal Development. Impact of adult educational level and socio-affective proximity on the effectiveness of tutoring. [PDF]
de póster presentado a VI International Conference “Early Childhood Care and Education”, Lomonosov Moscow State University –MSU (Moscow, Russia), Mayo 2017.Research problem.
Barajas-Esteban, Maria Carmen +1 more
core
Arterial dysgenesis and limb defects : Clinical and experimental examples [PDF]
Acknowledgements This article is dedicated to Dr David S. Packard Jr. With thanks to Dr John DeSesso, Dr Lewis B. Holmes, Dr Mark Levinsohn, Dr David S.
Hootnick, David R., Vargesson, Neil
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
After completing an introductory biostatistics course, public health students often need to take one or more follow-on courses focusing on specialized areas of biostatistics.
Qi Zheng
doaj +1 more source
A Decriptive Overview of Dynamic Assessment
Dynamic assessment (DA), deriving from the Vygotskian Sociocultural theoretical approach, has attracted considerable attention from researchers in the fields of psychology and general education, but it is still regarded as a novel approach within the ...
İsmail Mirici, Yelda Orhon
doaj +1 more source
Differential Expression Of Gap Junction mRNAs And Proteins In The Developing Murine Kidney And In Experimentally Induced Nephric Mesenchymes [PDF]
The expression of three gap junction (GJ) proteins, alpha-1 (Cx43), beta-1 (Cx32), and beta-2 (Cx26), and their transcripts were examined during the ontogeny of the mouse and rat kidney. These proteins were expressed in two non-overlapping patterns.
Gilbert, Scott F. +6 more
core +1 more source
Tree growth and management in Ugandan agroforestry systems: effects of root pruning on tree growth and crop yield [PDF]
Tree root pruning is a potential tool for managing below-ground competition when trees and crops are grown together in agroforestry systems. This study investigates its effects on growth and root distribution of Alnus acuminata (HB & K), Casuarina ...
Deans, J. Douglas +5 more
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ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source

