Results 41 to 50 of about 62,762 (291)

A Goldilocks approach to transdisciplinary learning

Journal of the European Honors Council
In today’s world, education is increasingly being called upon to do more. Beyond transmitting knowledge, we need to cultivate both capability and agency in learners to navigate the complexity and uncertainty of our time.
Jan-Peter Sandler
doaj   +3 more sources

Zone of Proximal Development and Scaffolding Online

, 2005
While developing our courses, we realized the importance of the zone of proximal development (Vygotsky, 1978) in supporting our students. Learners’ experiences and backgrounds influence the learning process by bringing together the current learning ...
Aandrea R. Bilics, Binta Colley, Carol M. Lerch   +2 more
core   +1 more source

ZONE OF PROXIMAL DEVELOPMENT IN TEACHING ENGLISH POETRY : AN OVERVIEW IN INDONESIAN HIGHER EDUCATION CONTEXT [PDF]

, 2022
The importance of teaching and learning activities, including Indonesian language learning cannot be underestimated . Many teachers who use a traditional method to teaching poetry devote the majority of the class time to "extrinsic" qualities of ...
Wello, M.Basri, Dollah, Syarifuddin, Bakri, fitriani   +2 more
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Zone of Proximal Development and Scaffolding Online

, 2009
While developing our courses, we realized the importance of the zone of proximal development (Vygotsky, 1978) in supporting our students. Learners’ experiences and backgrounds influence the learning process by bringing together the current learning ...
Andrea R. Bilics, Binta Colley, Carol M. Lerch   +2 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

La evaluación formativa y la Zona de Desarrollo Proximal

, 2019
Este artigo tem por objetivo apresentar as possíveis relações entre a avaliação formativa e a Zona de Desenvolvimento Proximal de Vygotsky. Como método de pesquisa, optou-se por utilizar a pesquisa especulativa, pois a intenção é produzir um texto ...
Rossetto, Hallynnee Héllenn Pires, Pedrochi, Wellen Eder, Pedrochi Junior, Osmar   +2 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Adult and child development in the zone of proximal development : Socratic dialogue in a playworld

, 2010
This article analyses adult and child development in the zone of proximal development in an educational practice based in Vygotsky's theories of play: the playworld educational practice.
Lecusay, Robert,, Ferholt, Beth,
core   +1 more source