Results 51 to 60 of about 202,233 (299)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Scaffolding, the Zone of Proximal Development, and Novice Programmers [PDF]

, 2015
The work, which is part of a doctoral research project, reported here aims to explore the learning strategies that novice computer programmers adopt when writing code, the ways in which they integrate knowledge, and the processes they employ when ...
Awbi, NK, Philpott, A, Whalley, JL
core  

Multi-Armed Bandits for Intelligent Tutoring Systems [PDF]

, 2015
We present an approach to Intelligent Tutoring Systems which adaptively personalizes sequences of learning activities to maximize skills acquired by students, taking into account the limited time and motivational resources.
Benjamin Clement, Didier Roy, Inria Bordeaux, Manuel Lopes, Pierre-yves Oudeyer   +4 more
core   +4 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

'Philosophy for children' as creating the zone of proximal development [PDF]

Psihološka Istraživanja, 2014
In this paper, we analyze the conception, objectives and methodology of the 'Philosophy for Children', a programme aimed at fostering critical thinking in children aged five to eighteen.
Pešić Jelena, Zrenjanin Ana
doaj   +1 more source

Teacher Feedback, Learner Dialogue, and the Zone of Proximal Development [PDF]

, 2012
リキャストなど口頭訂正フィードバックの第二言語習得過程における役割や効果についての研究は、これまで、いわゆるインプット－インタラクション－アウトプットのモデルを用いて行われてきた。しかし、このモデルでは談話が一元的な発話の積み重ねとして捉えられるため、訂正フィードバックの機能や仕組みが曖昧である。本稿では、教師の口頭訂正フィードバックを含む談話を、社会文化的理論（Sociocultural Theory）の視点で考察する。社会文化的理論では、談話には、時として問題解決を目的とした認知的活動の「場 ...
Nabei Toshiyo, 名部井 敏代
core   +1 more source

Gene regulatory network subcircuit controlling a dynamic spatial pattern of signaling in the sea urchin embryo [PDF]

, 2008
We dissect the transcriptional regulatory relationships coordinating the dynamic expression patterns of two signaling genes, wnt8 and delta, which are central to specification of the sea urchin embryo endomesoderm.
Alifragis, Davidson, Dawson, E. H. Davidson, Fisher, Giagtzoglou, Gyory, Howard-Ashby, Howard-Ashby, J. Smith, Kuo, Lee, Livi, Materna, McClay, Minokawa, Oellers, Oliveri, Osipovich, Peterson, Ransick, Revilla-i-Domingo, Rizzo, Robertson, Sea Urchin Genome Sequencing Consortium, Sherwood, Smith, Smith, Thirunavukkarasu, Tietze, Tu, Walton, Wikramanayake, Yu, Yuh   +34 more
core   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Reflections on the Ecolab and the Zone of Proximal Development [PDF]

, 2016
In 1999 we reported a study that explored the way that Vygotsky’s Zone of Proximal Development could be used to inform the design of an Interactive Learning Environment called the Ecolab.
Du Boulay, B, Luckin, R
core  

The position of graptolites within Lower Palaeozoic planktic ecosystems. [PDF]

, 1993
An integrated approach has been used to assess the palaeoecology of graptolites both as a discrete group and also as a part of the biota present within Ordovician and Silurian planktic realms.
Allison P.A., Baker A. de C., Bates D.E.B., Beckly A.J., Bergstrom J., Berry W.B.N., Berry W.B.N., Berry W.B.N., Bjerreskov M., Brenchley, Briggs D.E.G., Bulman O.M.B., Bulman O.M.B., Bulman O.M.D., Cloud P., Colbath G.K., Conway Morris S., Conway Morris S., Conway Morris S., Conway Morris S., Conway Morris S., Cooper R.A., Crowther P.R., Crowther P.R., Elles G.L., Erdtmann B.D., Erdtmann B.D., Erdtmann B.D., Finney S.C., Fortey R.A., Fortey R.A., Fortey R.A., Fortey R.A., Gurich G., Herr S.H., Jackson D.E., Jager H., Jager H., Kemp A.E.S., Kirk N. H., Kirk N.H., Kirk N.H., Kirk N.H., Koren T.N., Kozlowski R., Kozlowski R., Koztowski R., Koztowski R., Koztowski R., Leggett J.K., Lenz A.C., Loydell D.K., Mauchline J., Nicholson H.A., Palmer D., Rickards R.B., Rickards R.B., Rickards R.B., Rickards R.B., Rickards R.B., Rickards R.B., Rigby S., Rigby S., Rigby S., Rosen B.R., Ruedemann R., Semina H.J., Sheehan P.M., Siveter D.J., Stormer L., Towe K.M., Tsudy D.M., Urbanek A., Urbanek A., Urbanek A., Walters M., Wells M.J., Whittington H.B., Williams S.H., Williams S.H., Williams S.H., Williams S.H., Williams S.H., Winston J.E., Zalasiewicz J.A., Ziegler A.M.   +85 more
core   +1 more source