Results 41 to 50 of about 12,742 (223)

Systematic review of antiepileptic drugs’ safety and effectiveness in feline epilepsy [PDF]

, 2018
Understanding the efficacy and safety profile of antiepileptic drugs (AEDs) in feline epilepsy is a crucial consideration for managing this important brain disease.
A Klang, A Pakozdy, A Pakozdy, A Pakozdy, A Pellegrini, AD Quesnel, Akos Pakozdy, AM Wahle, AS Sawchuk, C Bertolani, CR Hooijmans, CW Dewey, D Hasegawa, D Hughes, D Moher, D Schwartz-Porsche, D Schwartz-Porsche, DB Roye, DE Cuff, DL Zoran, DM Boothe, DM Brewer, G Zaccara, G Zaccara, GE Solomon, GH Guyatt, H Volk, Holger A. Volk, JA Berlin, JA Wada, JAD Gasper, JM Ducote, KE Finnerty, KS Bailey, KS Bailey, LR Barnard, M Charalambous, M Charalambous, M Lowrie, M Podell, MA Cautela, MA Holmes, Marios Charalambous, MB Carnes, MJ Baho, NM van Gelder, O Engel, P Boydell, PN Papanikolaou, R Chou, S Cizinauskas, S Schriefl, S Wagner, SA Center, SD Ross, SF Bhatti, SM Cochrane, SM Cochrane, Sofie F. M. Bhatti   +58 more
core   +3 more sources

HLA genotype testing for carbamazepine, oxcarbazepine and eslicarbazepine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway, Cinzia Dello Russo, Nicholas Bass, Elvira Bramon, Helen Cross, Natalie Curley, Sarah Curran, Helen Davies, Jana De Villiers, William Evans, Bernhard Frank, Alice Groves, Judith Hayward, Jon Higham, Dyfrig A. Hughes, Shwe Sin Kyaw, Anthony G. Marson, Ailsa McLellan, Seth Mensah, Francis O'Neill, Jane Sargison, Sanjay M. Sisodiya, Jill Swan, Joanna M. Zakrewska, Munir Pirmohamed   +24 more
wiley   +1 more source

Neuroinflammation following anti-parkinsonian drugs in early Parkinson’s disease: a longitudinal PET study

Scientific Reports
The progression of neuroinflammation after anti-parkinsonian therapy on the Parkinson’s disease (PD) brain and in vivo evidence of the therapy purporting neuroprotection remain unclear.
Tatsuhiro Terada, Tomoyasu Bunai, Takanori Hashizume, Takashi Matsudaira, Masamichi Yokokura, Hirotsugu Takashima, Takashi Konishi, Tomokazu Obi, Yasuomi Ouchi   +8 more
doaj   +1 more source

Third generation antiepileptic drugs: mechanism of action, pharmacokinetics, interaction and use in childhood

Эпилепсия и пароксизмальные состояния, 2023
The review considers pharmacological characteristics of new antiepileptic drugs (AEDs) of the third generation such as eslicarbazepine, lacosamide, retigabine, perampanel, everolimus, brivaracetam, zonisamide.
Z. G. Tadtaeva, A. N. Galustyan, O. A. Gromova, I. S. Sardaryan   +3 more
doaj   +1 more source

Drug Critical Limits for Urgent Physician Notification

Clinical Pharmacology &Therapeutics, EarlyView.
Critical limits represent quantitative decision thresholds for drugs that require immediate clinician notification and potential life‐saving intervention. United States hospitals lack a national standard for drug critical limits. We collected critical limits from 417 US hospitals across all 50 states and Washington, D.C.; of these, 411 maintained drug ...
Elina Kuang, Yasmeen Ibrahim, Kyle Cheng, Gerald J. Kost   +3 more
wiley   +1 more source

Seizure outcome after switching antiepileptic drugs: A matched, prospective study. [PDF]

, 2016
OBJECTIVE: Outcomes after changing antiepileptic drugs (AEDs) have largely been studied in single cohort series. We recently reported the first study to examine this question in a controlled manner.
Finamore, Jon Marc, Mintzer, Scott, Nei, Maromi, Skidmore, Christopher T., Sperling, Michael R., Zhan, Tingting   +5 more
core   +2 more sources

A guide to neuromodulation in drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh, Irena Dolezawa, Manu Hegde, Lukas Imbach, Brian N. Lundstrom, Francesca Pizzo, Vikram R. Rao, Jaysingh Singh, Derek Southwell, Satsuke Watanabe, Birgit Frauscher   +10 more
wiley   +1 more source

Zonisamide

Reactions Weekly
Kadian R, Patel P, Kumar A.
europepmc   +2 more sources

Effectiveness and safety of cenobamate after conversion to monotherapy or dual therapy in real‐world clinical practice

Epileptic Disorders, EarlyView.
Abstract Objective Patients with drug‐resistant epilepsy (DRE) typically take multiple anti‐seizure medications (ASMs) and are at risk of treatment‐related adverse events (AEs). This study assessed the impact of cenobamate monotherapy or dual therapy in patients with drug‐resistant epilepsy.
Álvaro Sánchez‐Guijo Benavente, Guillermina García Martín, Estuardo Daniel Castro Ruiz, Pablo Cabezudo García, Yolanda López Moreno, José Carlos Estévez María, Irene Lorite Fuentes, Sergio Navarro Conti, Raquel Calle Calle, Alejandro Fernández Cabrera, Isabel Ros González, Dulce Campos Blanco, María Isabel Chamorro Muñoz, Pedro Jesús Serrano Castro   +13 more
wiley   +1 more source

Italian Wikipedia and epilepsy: an infodemiological study of online information-seeking behavior [PDF]

, 2018
Wikipedia is the most commonly accessed source of health information by both healthcare professionals and the lay public worldwide. We aimed to evaluate information-seeking behavior of Internet users searching the Italian Wikipedia for articles related ...
Bragazzi, Nicola Luigi, Brigo, Francesco, Galimberti, Carlo Andrea, Giussani, Giorgia, Lattanzi, Simona, Mecarelli, Oriano, Nardone, Raffaele, Pietrafusa, Nicola, Tassi, Laura   +8 more
core   +1 more source