Zonula occludens-1의 변화를 통한 interleukin-13의 족세포 투과도 증가
, 2013 Dept. of Medicine/박사Purpose: The aim of this study was to investigate whether pathologic changes in zonula occludens-1 (ZO-1) are induced by interleukin-13 (IL-13) in the experimental minimal-change nephrotic syndrome (MCNS) model and to determine ...
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Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances
MedComm, Volume 7, Issue 9, September 2026.Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait +5 more
wiley +1 more source
Electroacupuncture enhances the mitophagy of granulosa cells in premature ovarian insufficiency model mice by inactivating the hippo-yes-associated protein/transcriptional co-activator with postsynaptic density protein, drosophila disc large tumor suppressor, and zonula occludens-1 protein binding motif pathway. [PDF]
J Tradit Chin MedJiaman WU +6 more
europepmc +1 more source
Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets
MedComm, Volume 7, Issue 9, September 2026.Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li +3 more
wiley +1 more source
Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1. [PDF]
Oncol Lett, 2018 Zhang X +7 more
europepmc +1 more source
RNA‐Binding Proteins: Function, Biological Mechanisms, and Therapeutic Opportunities
MedComm, Volume 7, Issue 9, September 2026.RNA‐binding proteins (RBPs) regulate RNA stability, localization, translation, and splicing through intrinsic binding domains and interactions with diverse cellular partners. Their competitive and cooperative networks shape disease‐related RNA programs, especially in cancer.
Ling Li, Xiuli Yan, Qing Ji, Hui Zhang
wiley +1 more source
Zonula occludens-1, occludin and E-cadherin expression and organization in salivary glands with Sjögren's syndrome. [PDF]
J Histochem Cytochem, 2015 Mellas RE +4 more
europepmc +1 more source
Small, Volume 22, Issue 49, 1 September 2026.A microfluidic model of the glioblastoma (GBM) margin was developed to mimic patient‐specific blood‐brain tumor barrier (BBTB) function and drug response. The platform revealed inter‐patient variability in barrier integrity and drug sensitivity, offering a tool for personalized therapy evaluation in GBM.
Minsu Ryoo +16 more
wiley +1 more source
Targeting the tight junction protein, zonula occludens-1, with the connexin43 mimetic peptide, αCT1, reduces VEGF-dependent RPE pathophysiology. [PDF]
J Mol Med (Berl), 2017 Obert E +6 more
europepmc +1 more source
Akkermansia muciniphila and Its Bioactive Derivatives: Emerging Regulators of Healthy Aging
Aging Cell, Volume 25, Issue 9, September 2026.The beneficial gut bacterium Akkermansia muciniphila (AKK) declines with age but is enriched in healthy centenarians. Supplementation of AKK extends healthspan and alleviates age‐related decline through direct host–microbe interactions and its bioactive derivatives, which collectively enhance gut barrier integrity, restore metabolic homeostasis ...
Ting Zhang +7 more
wiley +1 more source