Probiotic lactic acid bacterial strains MG4693 and MG5474 alleviate atopic dermatitis by enhancing intestinal barrier integrity and modulating the immune system. [PDF]
Food Nutr ResYoon W +4 more
europepmc +1 more source
Silphium perfoliatum flavonoids alleviate LPS-induced injury via enhancing intestinal antioxidant capacity, barrier function, and regulating cecal microbiota in broilers. [PDF]
Poult SciLiu G +8 more
europepmc +1 more source
The PDZ2 domain of zonula occludens-1 and -2 is a phosphoinositide binding domain [PDF]
Cellular and Molecular Life Sciences, 2009 Zonula occludens proteins (ZO) are postsynaptic density protein-95 discs large-zonula occludens (PDZ) domain-containing proteins that play a fundamental role in the assembly of tight junctions and establishment of cell polarity.
Hui Lu +2 more
exaly +4 more sources
Zonula occludens-1 (ZO-1) is involved in morula to blastocyst transformation in the mouse [PDF]
Developmental Biology, 2008 It is unknown whether or not tight junction formation plays any role in morula to blastocyst transformation that is associated with development of polarized trophoblast cells and fluid accumulation.
Jeff Reese +2 more
exaly +4 more sources
Association of connexin36 and zonula occludens-1 with zonula occludens-2 and the transcription factor zonula occludens-1-associated nucleic acid-binding protein at neuronal gap junctions in rodent retina [PDF]
Neuroscience, 2006 Most gap junctions between neurons in mammalian retina contain abundant connexin36, often in association with the scaffolding protein zonula occludens-1. We now investigate co-association of connexin36, zonula occludens-1, zonula occludens-2 and Y-box transcription factor 3 (zonula occludens-1-associated nucleic acid-binding protein) in mouse and rat ...
Xinbo Li, James Imre Nagy, John Rash
exaly +3 more sources
Telmisartan Increases the Permeability of Endothelial Cells through Zonula Occludens-1
Biological and Pharmaceutical Bulletin, 2009 Angiotensin receptor-1 blockers (ARBs) have been used for the treatment of atherosclerosis. Tight junctions are very important in the regulation of cellular permeability which may have a profound role in atherosclerosis. The relationship between them is unresolved.
Yihua Wu, Chang Bian
exaly +4 more sources
Zonula Occludens‐1 and ‐2 Are Cytosolic Scaffolds That Regulate the Assembly of Cellular Junctions
Annals of the New York Academy of Sciences, 2009 The integrity of the tight junction barrier in epithelial and endothelial cells is critical to human health, but we still lack a detailed mechanistic knowledge of how the barrier is formed during development or responds to pathological and pharmacological insults. This limits our understanding of barrier dysfunction in disease and slows the development
James Anderson, Alan S Fanning
exaly +4 more sources
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Connexin45 Interacts with Zonula Occludens-1 in Osteoblastic Cells
Cell Communication & Adhesion, 2001Connexin43 (Cx43) and Cx45 are co-expressed in a number of different tissues. Studies demonstrated that Cx45 transfected ROS (ROS/Cx45) cells, were less permeable to low molecular weight dyes than untransfected ROS cells, that have gap junctions made of Cx43.
J G, Laing +4 more
openaire +2 more sources
Diminished zonula occludens-1 expression in the failing human heart
Cardiovascular Pathology, 2007Reduced expression of the major gap junction protein connexin 43 (Cx43) in the failing human heart may lead to arrhythmias and sudden cardiac death. Cx43 interacts with the actin binding protein, zonula occludens-1 (ZO-1), and it has recently been demonstrated that ZO-1 regulates the formation and function of Cx43 gap junctions.
James G, Laing +3 more
openaire +2 more sources