Results 141 to 150 of about 21,719 (253)
Zonula occludens-1의 변화를 통한 interleukin-13의 족세포 투과도 증가
Dept. of Medicine/박사Purpose: The aim of this study was to investigate whether pathologic changes in zonula occludens-1 (ZO-1) are induced by interleukin-13 (IL-13) in the experimental minimal-change nephrotic syndrome (MCNS) model and to determine ...
박세진
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Hypercholesterolaemic Serum Increases the Permeability of Endothelial Cells through Zonula Occludens-1 with Phosphatidylinositol 3-Kinase Signaling Pathway [PDF]
Recommended by Omar Benzakour Purpose. Hypercholesterolemia and tight junctions play important roles in atherosclerosis. But the relationship between these two factors is unclear.
Chang Bian +5 more
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Objectives: The cyclophosphamide (CYP)-induced model of cystitis in mice closely fits the symptoms of chronic bladder inflammation. Cystitis was recently found to be due to an altered gap junction protein in a rat model. Thus, this study was conducted to
Wen-Chi Chen +6 more
core +1 more source
Vancomycin Protects Against Lung Injury and Promotes Butyrate Metabolism
Transplanting the fecal microbiota of patients with lung injury into mice causes an increase in LPS in the mice's blood, thereby leading to chronic lung injury in the mice. Meanwhile, oral administration of vancomycin can enhance colonic butyrate metabolism and improve lung injury in mice.
Jianuo Chen +9 more
wiley +1 more source
The mechanism(s) by which angiotensin-converting enzyme (ACE) inhibitors prevent glomerular membrane loss of permselective function is still not understood.
Remuzzi, Andrea
core +1 more source
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley +1 more source
Roles of Microglia in Cerebral Small Vessel Disease
Chronic cerebral hypoperfusion triggers microglial activation in cerebral small vessel disease (CSVD). Activated microglia drive neuroinflammation, oxidative stress, and blood–brain barrier disruption, leading to white matter hyperintensities, enlarged perivascular spaces, and other neuroimaging features.
Chenyang Jin +7 more
wiley +1 more source
Scutellarein alleviates ulcerative colitis by reinforcing the intestinal barrier via the microbiota‐metabolite axis and suppressing PRMT1‐STAT3‐mediated inflammatory immune responses. ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colonic mucosa with an increasing global burden and limited therapeutic efficacy.
Yefan Zhou +12 more
wiley +1 more source
Beyond cell-cell adhesion: Emerging roles of the tight junction scaffold ZO-2
Wilhelm, Imola +6 more
core +1 more source
Involvement of Zonula Occludens proteins in metastatic lung cancer progression.
Au cours de la conversion métastatique des tumeurs épithéliales, les cellules tumorales acquièrent des capacités invasives/migratoires nouvelles. Ce changement phénotypique est associé au processus de TEM durant lequel les composants des jonctions ...
Lesage, Julien
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