Results 141 to 150 of about 21,719 (253)

Zonula occludens-1의 변화를 통한 interleukin-13의 족세포 투과도 증가

open access: yes, 2013
Dept. of Medicine/박사Purpose: The aim of this study was to investigate whether pathologic changes in zonula occludens-1 (ZO-1) are induced by interleukin-13 (IL-13) in the experimental minimal-change nephrotic syndrome (MCNS) model and to determine ...
박세진
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Hypercholesterolaemic Serum Increases the Permeability of Endothelial Cells through Zonula Occludens-1 with Phosphatidylinositol 3-Kinase Signaling Pathway [PDF]

open access: yes, 2009
Recommended by Omar Benzakour Purpose. Hypercholesterolemia and tight junctions play important roles in atherosclerosis. But the relationship between these two factors is unclear.
Chang Bian   +5 more
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Downregulation of tight junction protein zonula occludens-2 and urothelium damage in a cyclophosphamide-induced mouse model of cystitis

open access: yes, 2018
Objectives: The cyclophosphamide (CYP)-induced model of cystitis in mice closely fits the symptoms of chronic bladder inflammation. Cystitis was recently found to be due to an altered gap junction protein in a rat model. Thus, this study was conducted to
Wen-Chi Chen   +6 more
core   +1 more source

Vancomycin Protects Against Lung Injury and Promotes Butyrate Metabolism

open access: yesThe FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Transplanting the fecal microbiota of patients with lung injury into mice causes an increase in LPS in the mice's blood, thereby leading to chronic lung injury in the mice. Meanwhile, oral administration of vancomycin can enhance colonic butyrate metabolism and improve lung injury in mice.
Jianuo Chen   +9 more
wiley   +1 more source

Effect of angiotensin-converting enzyme inhibition on glomerular basement membrane permeability and distribution of zonula occludens-1 in MWF rats

open access: yes, 2000
The mechanism(s) by which angiotensin-converting enzyme (ACE) inhibitors prevent glomerular membrane loss of permselective function is still not understood.
Remuzzi, Andrea
core   +1 more source

Methylglyoxal Accumulation is Associated with Brain Inflammation after Myocardial Infarction with Sex and Regional Differences

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley   +1 more source

Roles of Microglia in Cerebral Small Vessel Disease

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
Chronic cerebral hypoperfusion triggers microglial activation in cerebral small vessel disease (CSVD). Activated microglia drive neuroinflammation, oxidative stress, and blood–brain barrier disruption, leading to white matter hyperintensities, enlarged perivascular spaces, and other neuroimaging features.
Chenyang Jin   +7 more
wiley   +1 more source

Scutellarein Alleviates Ulcerative Colitis by Reshaping Gut Microbiota and Regulating the PRMT1‐Mediated Th17/Treg Balance

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
Scutellarein alleviates ulcerative colitis by reinforcing the intestinal barrier via the microbiota‐metabolite axis and suppressing PRMT1‐STAT3‐mediated inflammatory immune responses. ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colonic mucosa with an increasing global burden and limited therapeutic efficacy.
Yefan Zhou   +12 more
wiley   +1 more source

Beyond cell-cell adhesion: Emerging roles of the tight junction scaffold ZO-2

open access: yes, 2013
Wilhelm, Imola   +6 more
core   +1 more source

Involvement of Zonula Occludens proteins in metastatic lung cancer progression.

open access: yes, 2016
Au cours de la conversion métastatique des tumeurs épithéliales, les cellules tumorales acquièrent des capacités invasives/migratoires nouvelles. Ce changement phénotypique est associé au processus de TEM durant lequel les composants des jonctions ...
Lesage, Julien
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