Results 71 to 80 of about 21,719 (253)

Curcumin Improves Epithelial Barrier Integrity of Caco-2 Monolayers by Inhibiting Endoplasmic Reticulum Stress and Subsequent Apoptosis

Gastroenterology Research and Practice, 2021
Curcumin is a natural polyphenol and is supposed to possess antioxidant, anti-inflammatory, anticancer, and antiapoptotic properties. Although some studies have reported the therapeutic effects of curcumin on ulcerative colitis (UC), the specific ...
Xinxin Zhou, Mengting Ren, Jinpu Yang, Hanghai Pan, Mosang Yu, Feng Ji   +5 more
doaj   +1 more source

EPITHELIAL BARRIER DYSFUNCTION IN EXPERIMENTAL ACUTE LUNG INJURY: CHANGES IN ZONULA OCCLUDENS-1 PROTEIN EXPRESSION

Medical Science of Ukraine (MSU)
Background. Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) remain the leading causes of mortality in critical conditions. A key mechanism in the development of ALI/ARDS is damage to the alveolar-capillary barrier, caused by disruption of the organization of tight junctions (TJs), which leads to persistent edema, hypoxemia, and ...
D.S. Ziablitsev, V.V. Mykhailovska, A.I. Kurchenko   +2 more
openaire   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

27-Hydroxycholesterol induces expression of zonula occludens-1 in monocytic cells via multiple kinases pathways

Scientific Reports, 2022
Zonula occludens (ZO)-1, a tight-junction protein (TJP), is expressed in dendritic cells (DCs) but not in monocytes, and 27-hydroxycholesterol (27OHChol) drives the differentiation of monocytes into DCs.
Hyok-rae Cho, Bo-Young Kim, Koanhoi Kim, Dongjun Lee, Seong-Kug Eo, Yonghae Son   +5 more
doaj   +1 more source

Effect of Cyclic Heat Exposure on the Growth Performance and Metabolism of Broilers Fed Palm Kernel Meal

Animal Research and One Health, EarlyView.
The aim of our study is to evaluate the interaction between HS and the incorporation of PKM in broiler chicken diets, as well as its effect on growth performance and metabolism. Based on the results obtained, PKM supplementation failed to mitigate the adverse effects of heat stress in broiler chickens. ABSTRACT The aim of this study was to evaluate the
Ahmed Mijiyawa, Elham Ghashghaei, Okasha Hamada, Huimin Wang, Lijing Sun, Yendouhamtchié Nadiedjoa, Dan Wang, Zhengkai Yue, Clarice Maa Maa Temhoul, Maxwell Ansong Okai, Muhammad Faisal Riaz, Felix Kwame Amevor, Wéré Pitala, Hai Lin   +13 more
wiley   +1 more source

L-Arginine protects ovine intestinal epithelial cells from lipopolysaccharide-induced intestinal barrier injury

Food and Agricultural Immunology, 2019
This research aims to explore the effect of L-arginine (Arg) on ovine intestinal epithelial cells (IOECs) from lipopolysaccharide (LPS)-induced intestinal barrier injury.
Hao Zhang, Yaqian Jin, Along Peng, Shuang Guo, Juan J. Loor, Hongrong Wang   +5 more
doaj   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

Astragalus polysaccharides and astragaloside IV ameliorates cyclophosphamide-induced mouse model of overactive bladder

Taiwanese Journal of Obstetrics & Gynecology, 2020
Objective: Previous studies have shown that Astragalus polysaccharides (APS) and Astragaloside IV (AS-IV) protect against inflammation-related cell damage and exhibit immune enhancement.
Yung-Hsiang Chen, Wen-Chi Chen, Po-Len Liu, Huey-Yi Chen   +3 more
doaj   +1 more source

Effects of different short-chain fatty acids (SCFA) on gene expression of proteins involved in barrier function in IPEC-J2

Porcine Health Management, 2022
Background Gut microbial anaerobic fermentation produces short-chain fatty acids (SCFA), which are important substrates for energy metabolism and anabolic processes in mammals.
Roberta Saleri, Paolo Borghetti, Francesca Ravanetti, Valeria Cavalli, Luca Ferrari, Elena De Angelis, Melania Andrani, Paolo Martelli   +7 more
doaj   +1 more source

P-glycoprotein regulates blood–testis barrier dynamics via its effects on the occludin/zonula occludens 1 (ZO-1) protein complex mediated by focal adhesion kinase (FAK) [PDF]

Proceedings of the National Academy of Sciences, 2011
The blood–testis barrier (BTB), one of the tightest blood–tissue barriers in the mammalian body, creates an immune-privileged site for postmeiotic spermatid development to avoid the production of antibodies against spermatid-specific antigens, many of which express transiently during spermiogenesis and spermiation.
Lee, WM, Chen, CY, Mruk, DD, Lui, WY, Su, L   +4 more
openaire   +4 more sources