Results 71 to 80 of about 25,883 (139)

Tight junctions expression is affected by active, inactive, and derivatives of Akkermansia muciniphila

Iranian Journal of Microbiology
Background and Objectives: Tight junctions (TJs) in the gastrointestinal tract are comprised of various junctional proteins including Occludin and Zonula Occludens (ZO-1) that have a critical role in epithelial barrier function. Gut microbiota and their
Farinaz Ghaderi, Zahra Hajebrahimi, Abolfazl Fateh, Fattah Sotoodehnejadnematalahi, Sara Ahmadi Badi, Somayeh Vaezijoze, Seyed Davar Siadat   +6 more
doaj   +1 more source

Role of Zonula Occludens (ZO) proteins in regulating kidney collecting duct principal cell proliferation and adhesion

, 2014
The role of tight junctions (TJs) in regulating epithelial cell proliferation in conjuction with scaffolding zonula occludens (ZO) proteins has come to light recently.
Qiao, Xiaomu
core   +1 more source

Decreased expression of zonula occludens-1 and occludin in the bladder urothelium of patients with interstitial cystitis/painful bladder syndrome

Journal of the Formosan Medical Association, 2014
Unique barrier properties of the urothelial surface membrane permit urine storage without contents leak into the bloodstream. Previous reports suggested that the bladder urothelial barrier might be compromised in interstitial cystitis/painful bladder ...
Jane-Dar Lee, Ming-Huei Lee
doaj   +1 more source

TAZ interacts with zonula occludens-1 and-2 proteins in a PDZ-1 dependent manner [PDF]

, 2010
The transcriptional coactivator TAZ recognizes L/PPxY motifs in transcription factors like Runx1/2 through its WW domain. We show that the first PDZ domain of zona occludens-1 (ZO-1) and 2 (ZO-2) interacts with the carboxy-terminal PDZ binding motif of ...
Boucherie, Ciska, Joël Vandekerckhove, Meerschaert, Kris, Gettemans, Jan, Remue, Eline, Kris Meerschaert, Jan Gettemans, Oka, Tsutomu, Vandekerckhove, Joël, Eline Remue, Tsutomu Oka, Ciska Boucherie, Sudol, Marius, Marius Sudol   +13 more
core   +1 more source

EPITHELIAL BARRIER DYSFUNCTION IN EXPERIMENTAL ACUTE LUNG INJURY: CHANGES IN ZONULA OCCLUDENS-1 PROTEIN EXPRESSION

Медична наука України
Background. Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) remain the leading causes of mortality in critical conditions. A key mechanism in the development of ALI/ARDS is damage to the alveolar-capillary barrier, caused by ...
D.S. Ziablitsev, V.V. Mykhailovska, A.I. Kurchenko   +2 more
doaj   +1 more source

Molecular Detection of Zonula Occludens Toxin (zot) Genes in Vibrio Cholerae O1 using PCR

Research in Molecular Medicine, 2017
Background: Zot (Zonula occludens toxin) is one of the secretion toxins of Vibrio cholerae in small intestine that binds to certain receptors in the epithelial cells and causes a change in the structure of tight junction.
Seyedeh Mahnaz Mousavi, Mehdi Zeinoddini, Azadeh Azizi, AliReza Saeedinia, Arina Monazah   +4 more
doaj  

Tight function zonula occludens-3 regulates cyclin D1–dependent cell proliferation

, 2011
Coordinated regulation of cell proliferation is vital for epithelial tissue homeostasis, and uncontrolled proliferation is a hallmark of carcinogenesis.
Parkos, Charles A.,, Nusrat, Asma,, Laur, Oskar,, Christopher T. Capaldo, Charles A. Parkos, Stefan Koch, Capaldo, Christopher T.,, Oskar Laur, Michael Kwon, Kwon, Michael,, Asma Nusrat, Koch, Stefan,   +11 more
core   +1 more source

The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy

Journal of Parkinson’s Disease, 2017
Background: Recent evidence suggests that Parkinson’s disease (PD) is associated with intestinal microbiota dysbiosis, abnormal intestinal permeability, and intestinal inflammation.
Phillip A. Engen, Hemraj B. Dodiya, Ankur Naqib, Christopher B. Forsyth, Stefan J. Green, Robin M. Voigt, Jeffrey H. Kordower, Ece A. Mutlu, Kathleen M. Shannon, Ali Keshavarzian   +9 more
doaj   +1 more source

Dosage composition for nasal delivery comprising vibrio cholera zonula occludens toxin as absorption enhancer

, 2000
A nasal dosage composition for nasal delivery comprising (A) a therapeutic agent; and (B) zonula occludens toxin, as well as a method for the use of the ...
Uzzau, Sergio, Fasano, Alessio, De Magistris, Maria Teresa, Rappuoli, Rino   +3 more
core  

Role of claudin species–specific dynamics in reconstitution and remodeling of the zonula occludens

, 2011
Tight-junction strands, which are organized into the beltlike cell–cell adhesive structure called the zonula occludens (TJ), create the paracellular permselective barrier in epithelial cells. The TJ is constructed on the basis of the zonula adherens (AJ)
Yuji Yamazaki, Reitaro Tokumasu, Hiroshi Kimura, Sachiko Tsukita   +3 more
core   +1 more source