Results 61 to 70 of about 25,883 (139)

Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin [PDF]

, 2006
Epithelial tight junctions participate in the regulation of gene expression by controlling the activity of transcription factors that can interact with junctional components.
Choquet, A, Balda, MS, Hollande, F, Matter, K, Tsapara, A, Kavanagh, E, Buchert, M   +6 more
core  

Effects of sevoflurane on lung epithelial permeability in experimental models of acute respiratory distress syndrome

Journal of Translational Medicine, 2023
Background Preclinical studies in acute respiratory distress syndrome (ARDS) have suggested that inhaled sevoflurane may have lung-protective effects and clinical trials are ongoing to assess its impact on major clinical outcomes in patients with ARDS ...
Ruoyang Zhai, Woodys Lenga Ma Bonda, Charlotte Leclaire, Cécile Saint-Béat, Camille Theilliere, Corinne Belville, Randy Coupet, Raiko Blondonnet, Damien Bouvier, Loic Blanchon, Vincent Sapin, Matthieu Jabaudon   +11 more
doaj   +1 more source

Tight junction protein levels of occludin, claudin-1 and zonula occludens-1 (ZO-1).

, 2014
(A) shows representative blots of occludin, claudin, zonula occludens-1 (ZO-1), and β-actin on 0, 3, 7 and 14 post-weaning, respectively. (B) shows relative tight junction proteins expression. Data are means ± SD.
Kan Xiao (623589), Cai-Hong Hu (623593), Le-Fei Jiao (623591), Ya-Lu Ke (623592), Ze-He Song (623590)   +4 more
core   +1 more source

The intestinal zonula occludens toxin (ZOT) receptor recognises non-native ZOT conformers and localises to the intercellular contacts [PDF]

, 2003
A preliminary structural analysis of Vibrio cholerae zonula occludens toxin (ZOT) was made by equilibrium denaturation and circular dichroism. ZOT is a structurally unstable protein in aqueous solution (ΔG(H2O) 3.82 kcal/mol), the putative intra- and ...
Alvin Lee, Christopher F van der Walle, Natalie White, Lee, Alvin, van der Walle, Christopher F, White, Natalie   +5 more
core   +1 more source

Diurnal testosterone oscillations gate drug delivery via phase separation of ZO-1 at the blood-testis barrier in mice

Communications Biology
The blood-testis barrier is essential for sperm development but also blocks the delivery of non-hormonal male contraceptives and other germ-cell-targeting therapies.
Zhaoyang Wang, Qihong Wu, Xun Tang, Lu Li, Jingxian Deng, Rufei Huang, Wanqing Lin, Yadong Huang, Yan Yang   +8 more
doaj   +1 more source

Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17.

PLoS ONE, 2016
Tight junction (TJ) dysfunction in the stratum granulosum leads to aberrant barrier function of the stratum corneum (SC) in the epidermis. However, it is unclear whether TJs are perturbed in atopic dermatitis (AD), a representative aberrant SC-related ...
Takuo Yuki, Megumi Tobiishi, Ayumi Kusaka-Kikushima, Yukiko Ota, Yoshiki Tokura   +4 more
doaj   +1 more source

Zonula occludens-1, occludin, and E-cadherin protein expression in biliary tract cancers

, 2009
The incidence of cholangiocarcinomas originating from intrahepatic and extrahepatic bile ducts, as well as of gallbladder carcinoma is increasing worldwide.
Németh, J., Szijártó, Attila, Győrffy, Hajnalka, Schaff, Zsuzsa, Németh, Zsuzsanna, Júlia Németh, Péter Kupcsulik, Péter Tátrai, Attila Szíjártó, Áron Somorácz, Kiss, András, Attila Marcell Szász, Szász, Attila Marcell, András Kiss, Kupcsulik, Péter, Hajnalka Győrffy, Somorácz, Áron, Németh J, Zsuzsa Schaff, Tátrai, Péter, Zsuzsanna Németh   +20 more
core   +1 more source

Tight junction proteins in glial tumors development and progression

Frontiers in Cellular Neuroscience
Tight junctions form a paracellular barrier in epithelial and endothelial cells, and they regulate the diffusion of fluids, molecules, and the penetration of cells across tissue compartments.
Jakub Moskal, Slawomir Michalak, Slawomir Michalak   +2 more
doaj   +1 more source

Cx43 and the Actin Cytoskeleton: Novel Roles and Implications for Cell-Cell Junction-Based Barrier Function Regulation

Biomolecules, 2020
Barrier function is a vital homeostatic mechanism employed by epithelial and endothelial tissue. Diseases across a wide range of tissue types involve dynamic changes in transcellular junctional complexes and the actin cytoskeleton in the regulation of ...
Randy E. Strauss, Robert G. Gourdie
doaj   +1 more source

Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia [PDF]

, 2012
ETOC: Our study reveals that ZO proteins in fully polarized cells regulate the assembly and contractility of the perijunctional actomyosin ring associated with the adherens junction.The structure and function of both adherens (AJ) and tight (TJ ...
Fanning, Alan S., Van Itallie, Christina M., Anderson, James M.   +2 more
core   +1 more source