Results 81 to 90 of about 25,883 (139)

Inhibition of MicroRNA‐155 Supports Endothelial Tight Junction Integrity Following Oxygen‐Glucose Deprivation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Brain microvascular endothelial cells form a highly selective blood brain barrier regulated by the endothelial tight junctions. Cerebral ischemia selectively targets tight junction protein complexes, which leads to significant damage to ...
Juan Carlos Pena‐Philippides, Amy Sabrina Gardiner, Ernesto Caballero‐Garrido, Rong Pan, Yiliang Zhu, Tamara Roitbak   +5 more
doaj   +1 more source

Distribution of the zot (zonula occludens toxin) gene among strains of Vibrio cholerae 01 and non-01

, 1993
The distribution of the zot gene that encodes the zonula occludens toxin, a newly described toxin of Vibrio cholerae, among clinical, environmental and food isolates of V. cholerae 01 and non-01 was investigated.
Karasawa, Tadahiro, Mihara, Tatsuya, Ramamurthy, T., Kurazonoa, Hisao, Balakrish Nair, G., Garg, Surabhi, Takeda, Yoshifumi   +6 more
core   +1 more source

Beyond cell-cell adhesion: Emerging roles of the tight junction scaffold ZO-2 [PDF]

, 2013
Wilhelm, Imola, Traweger, A., Krizbai, István Adorján, Wagner, R.N., Toepfer, S., Zweimueller-Mayer, J., Gehwolf, R.   +6 more
core   +2 more sources

Improved Intestinal Permeation of Cyclosporin a by FCIGRL-Modified Tight Junction Modulator in Rats

Pharmaceutics
Objectives: Cyclosporin A (CsA) is an immunosuppressive drug that is highly effective. CsA, similar to other drugs with limited oral bioavailability due to poor membrane permeability, requires the use of absorption enhancers in its formulations.
Dong-Ho Jeong, Jung-Woo Kim, Keon-Hyoung Song   +2 more
doaj   +1 more source

Affinity purification and partial characterization of the zonulin/zonula occludens toxin (Zot) receptor from human brain

, 2000
The intercellular tight junctions (TJs) of endothelial cells represent the limiting structure for the permeability of the blood-brain barrier (BBB). Although the BBB has been recognized as being the interface between the bloodstream and the brain, little
UZZAU, Sergio, Zielke HR, Wang W, Lu R, Vigorito R, Fasano A.   +5 more
core   +1 more source

Neuroprotective effects of salvianolic acids combined with Panax notoginseng saponins in cerebral ischemia/reperfusion rats concerning the neurovascular unit and trophic coupling

Brain and Behavior
Background The neurovascular unit (NVU) and neurovascular trophic coupling (NVTC) play a key regulatory role in brain injury caused by ischemic stroke.
Hongyang Chen, Zhen Liu, Lei Zhao, Zhuangzhuang Jia   +3 more
doaj   +1 more source

Podosome formation impairs endothelial barrier function by sequestering zonula occludens proteins. [PDF]

J Cell Physiol, 2020
Rui YN, Chen Y, Guo Y, Bock CE, Hagan JP, Kim DH, Xu Z.   +6 more
europepmc   +1 more source

Analysis of the Zonula occludens Toxin Found in the Genome of the Chilean Non-toxigenic Vibrio parahaemolyticus Strain PMC53.7. [PDF]

Front Cell Infect Microbiol, 2020
Pérez-Reytor D, Pavón A, Lopez-Joven C, Ramírez-Araya S, Peña-Varas C, Plaza N, Alegría-Arcos M, Corsini G, Jaña V, Pavez L, Del Pozo T, Bastías R, Blondel CJ, Ramírez D, García K.   +14 more
europepmc   +1 more source

Involvement of Zonula Occludens proteins in metastatic lung cancer progression.

, 2016
Au cours de la conversion métastatique des tumeurs épithéliales, les cellules tumorales acquièrent des capacités invasives/migratoires nouvelles. Ce changement phénotypique est associé au processus de TEM durant lequel les composants des jonctions ...
Lesage, Julien
core  

Anisakis simplex products impair intestinal epithelial barrier function and occludin and zonula occludens-1 localisation in differentiated Caco-2 cells. [PDF]

PLoS Negl Trop Dis, 2020
Carballeda-Sangiao N, Sánchez-Alonso I, Navas A, Arcos SC, de Palencia PF, Careche M, González-Muñoz M.   +6 more
europepmc   +1 more source