Results 161 to 170 of about 31,558 (238)

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation

Experimental Physiology, Volume 111, Issue 4, Page 1733-1745, 1 April 2026.
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh, Amir Arsalan Ghahari, Ehsan Zandi, Seyedeh Zeynab Rasouli, Shaghayegh Davari, Mobina Hoseinzadeh, Mir Alireza Nourazar   +6 more
wiley   +1 more source

Characterizing airway epithelial cultures grown on permeable inserts with different pore densities

Physiological Reports, Volume 14, Issue 7, April 2026.
Abstract In vitro airway epithelial models, such as air‐liquid interface (ALI) cultures, are widely used for disease modeling, therapeutic and toxicology testing, and studying epithelial‐environmental interactions. However, it remains unknown whether the pore density of the permeable membrane inserts, on which primary human bronchial epithelial cells ...
T. J. F. Guo, G. K. Singhera, J. Memar Vaghri, W. Y. Liang, J. M. Leung, D. R. Dorscheid   +5 more
wiley   +1 more source

ALOX15‐Derived Oxylipins Attenuate Macrophage Inflammatory Signaling Via a Gαq–PLC–PKC Pathway

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
ALOX15 expression and its downstream oxylipins, including 12‐HETE and 13‐HODE, are induced in intestinal epithelial and lamina propria immune cells during the early and middle phases of experimental colitis. These endogenous lipid mediators suppress lipopolysaccharide‐induced TNF‐α and IL‐6 production in macrophages without affecting cell viability ...
Adrian Hilman, Yoshiki Ishii, Bambang Dwi Wijatniko, Dina Mustika Rini, Takuya Suzuki   +4 more
wiley   +1 more source

Propofol improved hypoxia-impaired integrity of blood-brain barrier via modulating the expression and phosphorylation of zonula occludens-1. [PDF]

CNS Neurosci Ther, 2019
Chen W, Ju XZ, Lu Y, Ding XW, Miao CH, Chen JW.   +5 more
europepmc   +1 more source

Toll-Like Receptor 4 Reduces Occludin and Zonula Occludens 1 to Increase Retinal Permeability Both in vitro and in vivo. [PDF]

J Vasc Res, 2017
Liu L, Jiang Y, Steinle JJ.
europepmc   +1 more source

Annexin A1 Mitigates Blood-Brain Barrier Disruption in a Sepsis-Associated Encephalopathy Model by Enhancing the Expression of Occludin and Zonula Occludens-1 (ZO-1). [PDF]

CNS Neurosci Ther
Li Y, Zhou F, You J, Gong X.
europepmc   +1 more source

Connexin43 and zonula occludens-1 are targets of Akt in cardiomyocytes that correlate with cardiac contractile dysfunction in Akt deficient hearts. [PDF]

Biochim Biophys Acta Mol Basis Dis, 2018
Ock S, Lee WS, Kim HM, Park KS, Kim YK, Kook H, Park WJ, Lee TJ, Abel ED, Kim J.   +9 more
europepmc   +1 more source

Role of Rab13, Protein Kinase A, and Zonula Occludens-1 in Hepatitis E Virus Entry and Cell-to-Cell Spread: Comparative Analysis of Quasi-Enveloped and Non-Enveloped Forms. [PDF]

Pathogens
Nagashima S, Primadharsini PP, Takahashi M, Nishiyama T, Murata K, Okamoto H.   +5 more
europepmc   +1 more source

Effects of interleukin-13 and montelukast on the expression of zonula occludens-1 in human podocytes. [PDF]

Yonsei Med J, 2015
Park SJ, Saleem MA, Nam JA, Ha TS, Shin JI.   +4 more
europepmc   +1 more source

RBM38 is involved in TGF-β-induced epithelial-to-mesenchymal transition by stabilising zonula occludens-1 mRNA in breast cancer. [PDF]

Br J Cancer, 2017
Wu J, Zhou XJ, Sun X, Xia TS, Li XX, Shi L, Zhu L, Zhou WB, Wei JF, Ding Q.   +9 more
europepmc   +1 more source