Results 11 to 20 of about 132,552 (240)
, 2021 Code that was used for the bioinformatics analysis reported in Szydzik J et al. ATR inhibition enables complete tumour regression in ALK-driven NB mouse models, Nature Communications ...
JimmyVdEynden
core +1 more source
A direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling. [PDF]
, 2006 TopBP1-like proteins, which include Xenopus laevis Xmus101, are required for DNA replication and have been linked to replication checkpoint control. A direct role for TopBP1/Mus101 in checkpoint control has been difficult to prove, however, because of ...
Lindsay, Howard D. +5 more
core +1 more source
ATR-FTIR data of buccal cells - OPUS
, 2023 ATR-FTIR data from buccal cell ...
Maria Paraskevaidi (14586953)
core +1 more source
Regulation of Mec1 (ATR) signaling in budding yeast [PDF]
, 2014 Cells are continuously challenged by various sources of DNA damage that can contribute to cancer formation if not appropriately repaired. To cope with this threat, cells have conserved mechanisms called the DNA damage checkpoints that sense damaged DNA ...
Hustedt, Nicole
core +1 more source
FAA regulation analysis for ATR ETOPS validation [PDF]
, 2017 ATR is the current world leader in regional aviation. In order to maintain its leading role in the turboprop market and to expand its customers' portfolio in the United States, the granting of the Extended Twin-Engine Operations Performance Standards ...
Claramunt Segura, Jordi
core +1 more source
, 2014 Background: Ataxia-telangiectasia mutated (ATM), ataxia-telangiectasia mutated and rad3 related (ATR) and DNA-dependent protein kinase catalytic sub-unit (DNA-PKcs) play critical roles in DNA damage response (DDR) by linking DNA damage sensing to DDR ...
Moseley, P +19 more
core +1 more source
A bridge between tourism and nature conservation: boardwalks effects on coastal dune vegetation
, 2021 Several regulatory and management tools are commonly used to prevent negative effects of human trampling on sand dune habitats, but few studies have attempted to evaluate the effects of boardwalks on dune vegetation.
Stanisci, Angela +2 more
core +1 more source
ATR-FTIR Spectroscopic Studies of Polymer-Based Identification Cards [PDF]
, 2019 Counterfeit production of polymer identity cards poses a significant economic cost to society and a threat to national security. Identifying these counterfeits is a challenge for ‘frontline’ personnel who lack training in specialised document examination.
Hackett, M. +13 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source