Results 71 to 80 of about 4,007 (118)

Dual-Warhead Conjugate Based on Fibroblast Growth Factor 2 Dimer Loaded with α-Amanitin and Monomethyl Auristatin E Exhibits Superior Cytotoxicity towards Cancer Cells Overproducing Fibroblast Growth Factor Receptor 1. [PDF]

Int J Mol Sci, 2023
Nawrocka D, Krzyscik MA, Sluzalska KD, Otlewski J.   +3 more
europepmc   +1 more source

PINK1-Parkin-Mediated mitophagy alleviates hepatocyte injury induced by α-amanitin

Ecotoxicology and Environmental Safety
The death cap mushroom (Amanita phalloides) is one of the most toxic fungi worldwide, with α-amanitin (α-AMA) identified as its primary lethal toxin. Mitophagy selectively eliminates damaged mitochondria via the autophagy pathway and plays a critical ...
Yang Zhao, Ziheng Zou, Peng Wu, Zehui Li, Zhijie Liu, Zhengwang Yi, Juyu Wang, Yi Wu, Weijie Qu, Bundit Tengjaroensakul, Jian Sun, Xiaolong Gu   +11 more
doaj   +1 more source

Anti-CD37 α-amanitin-conjugated antibodies as potential therapeutic weapons for Richter syndrome.

Blood, 2022
Vaisitti T, Vitale N, Micillo M, Brandimarte L, Iannello A, Papotti MG, Jaksic O, Lopez G, Di Napoli A, Cutrin JC, Orlik C, Kulke M, Pahl A, Deaglio S.   +13 more
europepmc   +1 more source

BRAF inhibition sensitizes melanoma cells to α-amanitin via decreased RNA polymerase II assembly. [PDF]

Sci Rep, 2019
Frischknecht L, Britschgi C, Galliker P, Christinat Y, Vichalkovski A, Gstaiger M, Kovacs WJ, Krek W.   +7 more
europepmc   +1 more source

Development of Simultaneous Analytical Method of Three Polypeptide Toxins α-Amanitin, β-Amanitin and Phalloidin in Poisonous Mushrooms and Human Serum Using UHPLC-MS/MS. [PDF]

J Mass Spectrom
Ok HJ, Park EY, Shin Y, Kim JH, Song MH, Lee JH.   +5 more
europepmc   +1 more source

Chemoenzymatic Synthesis of 4,5-Dihydroxyisoleucine Fragment of α-Amanitin. [PDF]

Org Lett
Chao TH, Renata H.
europepmc   +1 more source

Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by α-amanitin. [PDF]

J Biol Chem, 2018
Liu X, Farnung L, Wigge C, Cramer P.
europepmc   +1 more source

Production of (15)N-labeled α-amanitin in Galerina marginata. [PDF]

Toxicon, 2015
Luo H, DuBois B, Sgambelluri RM, Angelos ER, Li X, Holmes D, Walton JD.   +6 more
europepmc   +1 more source

FGF2 Dual Warhead Conjugate with Monomethyl Auristatin E and α-Amanitin Displays a Cytotoxic Effect towards Cancer Cells Overproducing FGF Receptor 1. [PDF]

Int J Mol Sci, 2018
Świderska KW, Szlachcic A, Opaliński Ł, Zakrzewska M, Otlewski J.   +4 more
europepmc   +1 more source

Detection of α-, β-, and γ-amanitin in urine by LC-MS/MS using ¹⁵N₁₀-α-amanitin as the internal standard. [PDF]

Toxicon, 2018
Abbott NL, Hill KL, Garrett A, Carter MD, Hamelin EI, Johnson RC.   +5 more
europepmc   +1 more source