Results 51 to 60 of about 732,445 (126)
α-Amanitin-based Small Format-Drug Conjugates for Prostate Cancer Therapy: Enabling Anti-Tumor Activity by Tuning Pharmacokinetic Properties [PDF]
, 2021 Gallo F. α-Amanitin-based Small Format-Drug Conjugates for Prostate Cancer Therapy: Enabling Anti-Tumor Activity by Tuning Pharmacokinetic Properties.
Gallo, Francesca
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Effect of gut microbiota on α‐amanitin tolerance in Drosophila tripunctata
Ecology and Evolution, 2020 The bacterial gut microbiota of many animals is known to be important for many physiological functions including detoxification. The selective pressures imposed on insects by exposure to toxins may also be selective pressures on their symbiotic bacteria,
Logan H. Griffin, Laura K. Reed
doaj +1 more source
Transposable elements: Functional aspects and applications as drivers of crop innovation
Crop Science, Volume 66, Issue 2, March/April 2026.Abstract Transposable elements (TEs), which were once relegated to the status of genomic parasites, are today accepted as important agents of plant genome evolution and adaptation. This review integrates evidence pointing to their dual function as drivers of genetic diversity and instability, with a focus on their contribution to phenotypic innovation,
Flávia Layse Belém Medeiros +12 more
wiley +1 more source
Amanitin poisoning in the dog [PDF]
, 1975 So far, most experimental investigations concerning amanitin poisoning have been done in the mouse or in the rat. In order to obtain conditions which could be better compared to human intoxication, we chose the dog for experiments.
Faulstich, H. +3 more
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Upstream CB1R Regulation of β‐Adrenergic Memory Consolidation
Hippocampus, Volume 36, Issue 2, March 2026.ABSTRACT Object recognition memory (ORM) plays a key role in identifying familiar items and encoding episodic information. ORM consolidation depends on β‐adrenergic receptor (βAR) signaling and is associated with increased BDNF expression in the dorsal hippocampus.
Janine I. Rossato +9 more
wiley +1 more source
PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 499-515, March 2026.Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana +4 more
wiley +1 more source
Concise Chemoenzymatic Synthesis of 4,5-Dihydroxyisoleucine Fragment of α-Amanitin [PDF]
The ability of α-amanitin to potently inhibit RNA polymerase II (RNAP II) has elicited further research into its use as a novel payload for antibody-drug conjugates.
Hans, Renata, Tsung-Han, Chao
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Toxins, 2020 Amatoxins are known to be one of the main causes of serious to fatal mushroom intoxication. Thorough treatment, analytical confirmation, or exclusion of amatoxin intake is crucial in the case of any suspected mushroom poisoning.
Thomas P. Bambauer +3 more
doaj +1 more source
Genes to Cells, Volume 31, Issue 2, March 2026.In the giant Pleurodeles waltl genome, introns serve as “structural buffers,” absorbing transposable elements (TEs) to protect coding exons. While this enables “gene body inflation,” persistent TE accumulation eventually leads to transcriptional silencing and functional collapse, or “burst,” of the gene architecture.
Kazuto Bou, Kiyokazu Agata
wiley +1 more source
Determination of α-Amanitin in Serum and Liver by Multistage Linear Ion Trap Mass Spectrometry [PDF]
, 2016 This paper describes a rapid LC-MS/MS/MS method for the analysis of α-amanitin in serum and liver. Serum was initially prepared by precipitation of proteins with acetonitrile and subsequent removal of acetonitrile with methylene chloride.
Michael S. Filigenzi (2495755) +3 more
core +1 more source