Results 51 to 60 of about 4,007 (118)
Antibody–Drug Conjugates and Peptide–Drug Conjugates: Current Understandings and Future Perspectives
MedComm, Volume 7, Issue 8, August 2026.The graphic summarizes the design principles, intracellular trafficking, clinical progress, challenges, and future directions of antibody–drug conjugates (ADCs) and peptide–drug conjugates (PDCs). ADCs consist of a tumor‐targeting antibody, a chemical linker, and a potent payload, whereas PDCs use peptide ligands to deliver cytotoxic, radionuclide, or ...
Ruxi Zheng +9 more
wiley +1 more source
Predator–Microbe Dynamics Inform Strategies for Robust Synthetic Community Assembly
Environmental Microbiology, Volume 28, Issue 6, June 2026.This Review introduces ecological principles of predator–prey interactions as a new dimension in SynCom design. By linking microbial defence traits, encounter dynamics, and adaptive buffering, it outlines a framework for constructing predator‐resistant synthetic communities with enhanced resilience, stability, and functional performance under natural ...
Eleonora Egidi, Uffe N. Nielsen
wiley +1 more source
Aptamer-based surface plasmon resonance sensor for α-amanitin
Frontiers in Sustainable Food Systemsα-Amanitin is a highly toxic amatoxin associated with poisonous mushroom poisoning and represents a significant threat to food safety and public health.
Qian Li, Lei Lei, Sha Sha
doaj +1 more source
Phosphorylation Status of RNA Polymerase II Carboxyl-terminal Domain in Porcine Oocytes and Early Embryos [PDF]
Asian-Australasian Journal of Animal Sciences, 2012 Fertilization of the oocyte commences embryogenesis during which maternally inherited mRNAs are degraded and the embryonic genome is activated. Transcription of embryonic mRNA is initiated by embryonic genome activation (EGA).
Reza K. Oqani +4 more
doaj +1 more source
Convergence and parallelism in the evolution of plant metabolism
Journal of Integrative Plant Biology, Volume 68, Issue 4, Page 1013-1031, April 2026.Similar traits in different organisms may originate from shared ancestry or evolve independently. The terminology used to define phenotypic similarity is often confusing. This review attempts to clarify the definitions and present examples from plant domestication and specialized metabolism to explain how complex traits evolve repeatedly in plants ...
Federico Scossa +4 more
wiley +1 more source
Transposable elements: Functional aspects and applications as drivers of crop innovation
Crop Science, Volume 66, Issue 2, March/April 2026.Abstract Transposable elements (TEs), which were once relegated to the status of genomic parasites, are today accepted as important agents of plant genome evolution and adaptation. This review integrates evidence pointing to their dual function as drivers of genetic diversity and instability, with a focus on their contribution to phenotypic innovation,
Flávia Layse Belém Medeiros +12 more
wiley +1 more source
PLoS ONE, 2017 Amanita ballerina and A. brunneitoxicaria spp. nov. are introduced from Thailand. Amanita fuligineoides is also reported for the first time from Thailand, increasing the known distribution of this taxon.
Benjarong Thongbai +6 more
doaj +1 more source
Upstream CB1R Regulation of β‐Adrenergic Memory Consolidation
Hippocampus, Volume 36, Issue 2, March 2026.ABSTRACT Object recognition memory (ORM) plays a key role in identifying familiar items and encoding episodic information. ORM consolidation depends on β‐adrenergic receptor (βAR) signaling and is associated with increased BDNF expression in the dorsal hippocampus.
Janine I. Rossato +9 more
wiley +1 more source
PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 499-515, March 2026.Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana +4 more
wiley +1 more source
Genes to Cells, Volume 31, Issue 2, March 2026.In the giant Pleurodeles waltl genome, introns serve as “structural buffers,” absorbing transposable elements (TEs) to protect coding exons. While this enables “gene body inflation,” persistent TE accumulation eventually leads to transcriptional silencing and functional collapse, or “burst,” of the gene architecture.
Kazuto Bou, Kiyokazu Agata
wiley +1 more source