Results 31 to 40 of about 4,007 (118)

An investigation of a food poisoning by Galerina sulciceps

open access: yesZhongguo shipin weisheng zazhi, 2020
Objective To investigate a food poisoning caused by wild mushrooms and to identify the risk factors. Methods Epidemiological investigation, morphological and phylogenetic identification, and laboratory testing were taken to analyze the poisoning event ...
Zhifan HE   +7 more
doaj   +1 more source

Morphology, Multilocus Phylogeny, and Toxin Analysis Reveal Amanita albolimbata, the First Lethal Amanita Species From Benin, West Africa

open access: yesFrontiers in Microbiology, 2020
Many species of Amanita sect. Phalloideae (Fr.) Quél. cause death of people after consumption around the world. Amanita albolimbata, a new species of A. sect. Phalloideae from Benin, is described here.
Jean Evans I. Codjia   +8 more
doaj   +1 more source

The Role of Ferroptosis in Hepatocyte Injury Induced by α-Amanitin

open access: yesFayixue Zazhi
ObjectiveTo explore whether ferroptosis is involved in α-amanitin-induced hepatocyte injury by detecting iron deposition in mice liver tissues, oxidative stress indicators in hepatocytes and L-02 cells, and expressions of ferroptosis-related proteins ...
WANG Hao-wei   +4 more
doaj   +1 more source

The occurrence of ansamers in the synthesis of cyclic peptides

open access: yesNature Communications, 2022
The occurrence of isomers of the bicyclic octapeptide α-amanitin, which presents a macrolactam with a tryptathionine cross-link forming a handle, has been reported under the term of atropoisomers.
Guiyang Yao   +6 more
doaj   +1 more source

Detection and analysis of amatoxins in 3 species of Lepiota from Chuxiong, Yunnan Province

open access: yesZhongguo shipin weisheng zazhi
ObjectiveTo analyze the content of 6 kinds of amatoxins in 3 species of Lepiota collected from Chuxiong of Yunnan Province.MethodsThe collected mushrooms were baked and dried at 45 ℃, and species identification was carried out by morphological and ...
XU Ping   +6 more
doaj   +1 more source

Investigating the phylogenetic history of toxin tolerance in mushroom‐feeding Drosophila

open access: yesEcology and Evolution, 2023
Understanding how and when key novel adaptations evolved is a central goal of evolutionary biology. Within the immigrans‐tripunctata radiation of Drosophila, many mushroom‐feeding species are tolerant of host toxins, such as cyclopeptides, that are ...
Theresa Erlenbach   +7 more
doaj   +1 more source

Establishment of Indirect Competitive ELISA Method for Detecting Amanitin in Mushroom

open access: yesShipin gongye ke-ji, 2022
Objective: This study aims to establish an indirect competitive enzyme-linked immunosorbent assay for the detection of amanitin (AMA) in mushroom. Methods: In this study, the hapten was obtained by introducing 6-aminocaproic acid into the carboxyl ...
Hebing LIU   +3 more
doaj   +1 more source

Identification of Decrease in TRiC Proteins as Novel Targets of Alpha-Amanitin-Derived Hepatotoxicity by Comparative Proteomic Analysis In Vitro

open access: yesToxins, 2021
Alpha-amanitin (α-AMA) is a cyclic peptide and one of the most lethal mushroom amatoxins found in Amanita phalloides. α-AMA is known to cause hepatotoxicity through RNA polymerase II inhibition, which acts in RNA and DNA translocation. To investigate the
Doeun Kim   +5 more
doaj   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

open access: yesChemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Determination of Amatoxins in Lepiota brunneoincarnata and Lepiota venenata by High-Performance Liquid Chromatography Coupled with Mass Spectrometry

open access: yesMycobiology, 2020
Three hepatic failure poisoning incidents caused by Lepiota brunneoincarnata and Lepiota venenata mushrooms have been occurred in China in 2017, L. venenata has been described as a new species.
Pan Long   +7 more
doaj   +1 more source

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