Results 31 to 40 of about 732,445 (126)
Frontiers in Microbiology, 2020 Many species of Amanita sect. Phalloideae (Fr.) Quél. cause death of people after consumption around the world. Amanita albolimbata, a new species of A. sect. Phalloideae from Benin, is described here.
Jean Evans I. Codjia +8 more
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Beilstein Journal of Organic Chemistry, 2018 RGD-α-amanitin and isoDGR-α-amanitin conjugates were synthesized by joining integrin ligands to α-amanitin via various linkers and spacers. The conjugates were evaluated for their ability to inhibit biotinylated vitronectin binding to the purified αVβ3 ...
Lizeth Bodero +9 more
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The occurrence of ansamers in the synthesis of cyclic peptides
Nature Communications, 2022 The occurrence of isomers of the bicyclic octapeptide α-amanitin, which presents a macrolactam with a tryptathionine cross-link forming a handle, has been reported under the term of atropoisomers.
Guiyang Yao +6 more
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Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by α-amanitin. [PDF]
, 2018 RNA polymerase II (Pol II) is the central enzyme that transcribes eukaryotic protein-coding genes to produce mRNA. The mushroom toxin α-amanitin binds Pol II and inhibits transcription at the step of RNA chain elongation.
Lucas Farnung +11 more
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The Role of Ferroptosis in Hepatocyte Injury Induced by α-Amanitin
Fayixue ZazhiObjectiveTo explore whether ferroptosis is involved in α-amanitin-induced hepatocyte injury by detecting iron deposition in mice liver tissues, oxidative stress indicators in hepatocytes and L-02 cells, and expressions of ferroptosis-related proteins ...
WANG Hao-wei +4 more
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Investigating the phylogenetic history of toxin tolerance in mushroom‐feeding Drosophila
Ecology and Evolution, 2023 Understanding how and when key novel adaptations evolved is a central goal of evolutionary biology. Within the immigrans‐tripunctata radiation of Drosophila, many mushroom‐feeding species are tolerant of host toxins, such as cyclopeptides, that are ...
Theresa Erlenbach +7 more
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Establishment of Indirect Competitive ELISA Method for Detecting Amanitin in Mushroom
Shipin gongye ke-ji, 2022 Objective: This study aims to establish an indirect competitive enzyme-linked immunosorbent assay for the detection of amanitin (AMA) in mushroom. Methods: In this study, the hapten was obtained by introducing 6-aminocaproic acid into the carboxyl ...
Hebing LIU +3 more
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Detection and analysis of amatoxins in 3 species of Lepiota from Chuxiong, Yunnan Province
Zhongguo shipin weisheng zazhiObjectiveTo analyze the content of 6 kinds of amatoxins in 3 species of Lepiota collected from Chuxiong of Yunnan Province.MethodsThe collected mushrooms were baked and dried at 45 ℃， and species identification was carried out by morphological and ...
XU Ping +6 more
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Toxins, 2021 Alpha-amanitin (α-AMA) is a cyclic peptide and one of the most lethal mushroom amatoxins found in Amanita phalloides. α-AMA is known to cause hepatotoxicity through RNA polymerase II inhibition, which acts in RNA and DNA translocation. To investigate the
Doeun Kim +5 more
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Mycobiology, 2020 Three hepatic failure poisoning incidents caused by Lepiota brunneoincarnata and Lepiota venenata mushrooms have been occurred in China in 2017, L. venenata has been described as a new species.
Pan Long +7 more
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