Results 21 to 30 of about 4,007 (118)

Differential Expression of Amanitin Biosynthetic Genes and Novel Cyclic Peptides in Amanita molliuscula

open access: yesJournal of Fungi, 2021
Amanita molliuscula is a basal species of lethal Amanita and intrigues the field because it does not produce discernable α-amanitin when inspected by High Performance Liquid Chromatography (HPLC), which sets it apart from all known amanitin-producing ...
Yunjiao Lüli   +5 more
doaj   +1 more source

Toxicity and urinary metabolites of α-amanitin in mice

open access: yesZhongguo gonggong weisheng, 2022
ObjectiveTo explore toxicity and urinary metabolites of α-amanitin in mice with a 21-day toxicological experiment. MethodsTwenty ICR male mice were randomly divided into a control (n = 5) and three median lethal dose (LD50) groups (5 in each group) with ...
Zhi-jun WU, Wen-jin ZHAO, Hai-jiao LI
doaj   +1 more source

Long-Term Resistance of Drosophila melanogaster to the Mushroom Toxin Alpha-Amanitin. [PDF]

open access: yesPLoS ONE, 2015
Insect resistance to toxins exerts not only a great impact on our economy, but also on the ecology of many species. Resistance to one toxin is often associated with cross-resistance to other, sometimes unrelated, chemicals. In this study, we investigated
Chelsea L Mitchell   +5 more
doaj   +1 more source

Amanitins in Wild Mushrooms: The Development of HPLC-UV-EC and HPLC-DAD-MS Methods for Food Safety Purposes

open access: yesFoods, 2022
Mushroom poisoning remains a serious food safety and health concern in some parts of the world due to its morbidity and mortality. Identification of mushroom toxins at an early stage of suspected intoxication is crucial for a rapid therapeutic decision ...
Isabel Barbosa   +3 more
doaj   +1 more source

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos. [PDF]

open access: yesAdv Sci (Weinh)
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Yuan S   +8 more
europepmc   +2 more sources

Calculating RNA degradation rates using large-scale normalization in mouse embryonic stem cells

open access: yesSTAR Protocols, 2023
Summary: Data normalization is critical to the process of estimating RNA degradation by analyzing RNA levels when transcription is blocked. Here, we present a protocol for measuring mRNA degradation rates, optimized for mouse embryonic stem cells, using ...
Juliane Oliveira Viegas   +3 more
doaj   +1 more source

Mycotoxins in Basidiomycete Mycelium and Fruiting Bodies: Implications for Eu Novel Food Assessment and Selected International Regulatory Frameworks. [PDF]

open access: yesCompr Rev Food Sci Food Saf
ABSTRACT Advances in technology have enabled the efficient and sustainable production of basidiomycete vegetative mycelium, particularly from Pleurotus species, as a novel food source. However, mycelium has yet to receive regulatory approval in many global markets, requiring a better understanding of factors affecting its safety.
Berglund NEW, Lankinen PV, Mikkonen KS.
europepmc   +2 more sources

Profiling of Amatoxins and Phallotoxins in the Genus Lepiota by Liquid Chromatography Combined with UV Absorbance and Mass Spectrometry

open access: yesToxins, 2014
Species in the mushroom genus Lepiota can cause fatal mushroom poisonings due to their content of amatoxins such as α-amanitin. Previous studies of the toxin composition of poisonous Lepiota species relied on analytical methods of low sensitivity or ...
R. Michael Sgambelluri   +5 more
doaj   +1 more source

Investigation of a mushroom poisoning incident caused by Amanita fuliginea in Guizhou Province

open access: yesZhongguo shipin weisheng zazhi, 2023
ObjectiveTo provide support and reference for the diagnosis, investigation, laboratory testing, and prevention of toxic mushroom poisoning in Guizhou, an Amanita fuliginea poisoning incident in Bijie, Guizhou Province was investigated.MethodsAn ...
ZHU Shu   +4 more
doaj   +1 more source

Diversity of MSDIN family members in amanitin-producing mushrooms and the phylogeny of the MSDIN and prolyl oligopeptidase genes

open access: yesBMC Genomics, 2020
Background Amanitin-producing mushrooms, mainly distributed in the genera Amanita, Galerina and Lepiota, possess MSDIN gene family for the biosynthesis of many cyclopeptides catalysed by prolyl oligopeptidase (POP). Recently, transcriptome sequencing has
Zhengmi He   +5 more
doaj   +1 more source

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