Results 21 to 30 of about 4,007 (118)
Amanita molliuscula is a basal species of lethal Amanita and intrigues the field because it does not produce discernable α-amanitin when inspected by High Performance Liquid Chromatography (HPLC), which sets it apart from all known amanitin-producing ...
Yunjiao Lüli +5 more
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Toxicity and urinary metabolites of α-amanitin in mice
ObjectiveTo explore toxicity and urinary metabolites of α-amanitin in mice with a 21-day toxicological experiment. MethodsTwenty ICR male mice were randomly divided into a control (n = 5) and three median lethal dose (LD50) groups (5 in each group) with ...
Zhi-jun WU, Wen-jin ZHAO, Hai-jiao LI
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Long-Term Resistance of Drosophila melanogaster to the Mushroom Toxin Alpha-Amanitin. [PDF]
Insect resistance to toxins exerts not only a great impact on our economy, but also on the ecology of many species. Resistance to one toxin is often associated with cross-resistance to other, sometimes unrelated, chemicals. In this study, we investigated
Chelsea L Mitchell +5 more
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Mushroom poisoning remains a serious food safety and health concern in some parts of the world due to its morbidity and mortality. Identification of mushroom toxins at an early stage of suspected intoxication is crucial for a rapid therapeutic decision ...
Isabel Barbosa +3 more
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The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos. [PDF]
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Yuan S +8 more
europepmc +2 more sources
Calculating RNA degradation rates using large-scale normalization in mouse embryonic stem cells
Summary: Data normalization is critical to the process of estimating RNA degradation by analyzing RNA levels when transcription is blocked. Here, we present a protocol for measuring mRNA degradation rates, optimized for mouse embryonic stem cells, using ...
Juliane Oliveira Viegas +3 more
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Mycotoxins in Basidiomycete Mycelium and Fruiting Bodies: Implications for Eu Novel Food Assessment and Selected International Regulatory Frameworks. [PDF]
ABSTRACT Advances in technology have enabled the efficient and sustainable production of basidiomycete vegetative mycelium, particularly from Pleurotus species, as a novel food source. However, mycelium has yet to receive regulatory approval in many global markets, requiring a better understanding of factors affecting its safety.
Berglund NEW, Lankinen PV, Mikkonen KS.
europepmc +2 more sources
Species in the mushroom genus Lepiota can cause fatal mushroom poisonings due to their content of amatoxins such as α-amanitin. Previous studies of the toxin composition of poisonous Lepiota species relied on analytical methods of low sensitivity or ...
R. Michael Sgambelluri +5 more
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Investigation of a mushroom poisoning incident caused by Amanita fuliginea in Guizhou Province
ObjectiveTo provide support and reference for the diagnosis, investigation, laboratory testing, and prevention of toxic mushroom poisoning in Guizhou, an Amanita fuliginea poisoning incident in Bijie, Guizhou Province was investigated.MethodsAn ...
ZHU Shu +4 more
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Background Amanitin-producing mushrooms, mainly distributed in the genera Amanita, Galerina and Lepiota, possess MSDIN gene family for the biosynthesis of many cyclopeptides catalysed by prolyl oligopeptidase (POP). Recently, transcriptome sequencing has
Zhengmi He +5 more
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