Results 41 to 50 of about 732,445 (126)
ObjectiveTo establish an analytical method for 9 mushroom toxins in wild fungus by liquid chromatography-tandem mass spectrometry (LC-MS/MS) including 5 acute liver failure toxins (α-amanitin, β-amanitin, γ-amanitin, phallacidin and phalloidin) and 4 ...
XU Xiaomin +5 more
doaj +1 more source
The TOR pathway may be central to the evolution of α-amanitin resistance in the DGRP lines. [PDF]
The schematic represents a suggested model for how α-amanitin resistance interplays with the TOR pathway via three of the top candidate genes suggested by our GWAS: widerborst, Tequila, and Megalin.
Catrina E. Latuszek (3798262) +13 more
core +1 more source
The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan +8 more
wiley +1 more source
Antiproliferative Effect of pHLIP-Amanitin [PDF]
Toxins could be effective anticancer drugs, if their selective delivery into cancer cells could be achieved. We have shown that the energy of membrane-associated folding of water-soluble membrane peptides of the pHLIP (pH low insertion peptide) family ...
Moshnikova, Valentina +3 more
core +2 more sources
Deaths from the accidental ingestion of poisonous Amanita mushrooms occur every year due to the lack of a specific antidote against α-amanitin poisoning.
Yang Li +8 more
doaj +1 more source
Investigation and analysis of a poisoning incident caused by Amanita exitialis in Meizhou
ObjectiveTo investigate a mushroom poisoning incident in Meizhou City, Guangdong Province in 2022, and provide a scientific basis for the prevention and control measures.MethodsEpidemiological investigations were carried out on the causes of poisoning ...
HU Bei +8 more
doaj +1 more source
Predator–Microbe Dynamics Inform Strategies for Robust Synthetic Community Assembly
This Review introduces ecological principles of predator–prey interactions as a new dimension in SynCom design. By linking microbial defence traits, encounter dynamics, and adaptive buffering, it outlines a framework for constructing predator‐resistant synthetic communities with enhanced resilience, stability, and functional performance under natural ...
Eleonora Egidi, Uffe N. Nielsen
wiley +1 more source
α-amanitin induces hepatotoxicity via PPAR-γ inhibition and NLRP3 inflammasome activation
Mushroom poisoning, predominantly caused by α-amanitin, is a critical food safety concern in worldwide, with severe cases leading to hepatotoxicity and fatalities.
Haowei Wang +9 more
doaj +1 more source
Poisoning due to mushroom consumption is uncommon, but it causes death by causing acute liver failure (ALF). The ingestion of Amanita phalloides, is one of the ultimate frequent causes of mushroom poisoning globally.
Afrah Thiab Hlail
doaj +1 more source
Convergence and parallelism in the evolution of plant metabolism
Similar traits in different organisms may originate from shared ancestry or evolve independently. The terminology used to define phenotypic similarity is often confusing. This review attempts to clarify the definitions and present examples from plant domestication and specialized metabolism to explain how complex traits evolve repeatedly in plants ...
Federico Scossa +4 more
wiley +1 more source

