Stapling Cysteine[2,4] Disulfide Bond of α-Conotoxin LsIA and Its Potential in Target Delivery
Marine Drugsα-Conotoxins, as selective nAChR antagonists, can be valuable tools for targeted drug delivery and fluorescent labeling, while conotoxin-drug or conotoxin-fluorescent conjugates through the disulfide bond are rarely reported.
Xin Sun +6 more
doaj +1 more source
Programmed Aptamer Screening, Characterization, and Rapid Detection for α-Conotoxin MI [PDF]
, 2022 Han Guo +10 more
openalex +1 more source
Disulfide Bond and Topological Isomerization of the Conopeptide PNID: Disulfide Bonds with a Twist. [PDF]
, 2017 Ph.D. Thesis.
Espiritu, Michael J.
core
Alanine-Scanning Mutagenesis of α-Conotoxin GI Reveals the Residues Crucial for Activity at the Muscle Acetylcholine Receptor [PDF]
, 2018 Jiong Ning +6 more
openalex +1 more source
Using Constellation Pharmacology to Characterize a Novel α-Conotoxin from Conus ateralbus
Marine DrugsThe venom of cone snails has been proven to be a rich source of bioactive peptides that target a variety of ion channels and receptors. α-Conotoxins (αCtx) interact with nicotinic acetylcholine receptors (nAChRs) and are powerful tools for investigating ...
Jorge L. B. Neves +19 more
doaj +1 more source
On-resin strategy to label α-conotoxins: Cy5-RgIA, a potent α9α10 nicotinic acetylcholine receptor imaging probe. [PDF]
Aust J Chem, 2020 Muttenthaler M +5 more
europepmc +1 more source
The allosteric activation of α7 nAChR by α-conotoxin MrIC is modified by mutations at the vestibular site [PDF]
, 2021 Alican Gulsevin +6 more
openalex +1 more source
Determination of the α-Conotoxin Vc1.1 Binding Site on the α9α10 Nicotinic Acetylcholine Receptor
, 2013 Rilei Yu +4 more
openalex +1 more source