Results 71 to 80 of about 1,000,648 (145)

Κριτική - Έτος Α' τευχ. 1-12 (15 Ιουνίου 1923 - 30 Μαΐου 1924)

, 1923
Στο Έτος Α’ περιλαμβάνονται 12 ...

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Difluoromethylornithine prevents the down-regulation of type 1 interferon receptors: A possible mechanism for a synergistic antiproliferative effect

, 1990
Type I interferon and difluoromethylornithine have been shown to exert an antiproliferative effect, both alone and in combination, in several tumor cell lines.
Lai, M. C., Minchin, R. F., Dilollo, D. L., Beilharz, M. W.   +3 more
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マウスにおけるN-Butyl-N-(4-hydroxybutyl)nitrosamine膀胱発癌に対するα-Difluoromethylornithineの抑制効果

, 1987
マウスにおけるN-Butyl-N-(4-hydroxybutyl) nitrosamine (BBN)膀胱発癌に対するα-Difluoromethylornithine (DFMO)の抑制効果を調べた.8週齢のWistar系雄性ラット50匹に0.05%BBN含有飲料水を, 4週間与えた後, 2群に分け, 1群には0.1%DFMO含有飲料水を, 他群には飲料水をそれぞれ自由に与えながら, CE-2固型飼料で, 60週まで飼育後, 屠殺して膀胱腫瘍の発生状況を観察した.DFMOは, BBN膀胱発癌において,
MATSUSHIMA, Masahiro, TAJIMA, Masaharu, MATSUHASHI, Tsutomu, YAGISHITA, Tsuguo, KAWAHARA, Masami   +4 more
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Polyamines Are Implicated in the Emergence of the Embryo from Obligate Diapause

, 2011
Embryonic diapause is a poorly understood phenomenon of reversible arrest of embryo development prior to implantation. In many carnivores, such as the mink (Neovison vison), obligate diapause characterizes each gestation.
Pavine L. C. Lefèvre, Marie-France Palin, Gustavo Turecki, Gary Chen, Bruce D. Murphy   +4 more
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Poster Sessions

HemaSphere, Volume 9, Issue S1, June 2025.
wiley   +1 more source

Perspective on this Article from Longitudinal Assessment of Air Conduction Audiograms in a Phase III Clinical Trial of Difluoromethylornithine and Sulindac for Prevention of Sporadic Colorectal Adenomas

, 2008
Perspective on this Article from Longitudinal Assessment of Air Conduction Audiograms in a Phase III Clinical Trial of Difluoromethylornithine and Sulindac for Prevention of Sporadic Colorectal ...
Christine E. McLaren (7924316), Sharon Fujikawa-Brooks (15092034), Eugene W. Gerner (14911290), Frank L. Meyskens (1307922), Daniel Pelot (15092031), Wen-Pin Chen (286916), Daniel L. Gillen (11083848)   +6 more
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Perspective on this Article from Risk of Cardiovascular Events in a Randomized Placebo-Controlled, Double-Blind Trial of Difluoromethylornithine plus Sulindac for the Prevention of Sporadic Colorectal Adenomas

, 2009
Perspective on this Article from Risk of Cardiovascular Events in a Randomized Placebo-Controlled, Double-Blind Trial of Difluoromethylornithine plus Sulindac for the Prevention of Sporadic Colorectal ...
Christine E. McLaren (7924316), Eugene W. Gerner (14911290), Frank L. Meyskens (1307922), Daniel Pelot (15092031), Wen-Pin Chen (286916), Jason A. Zell (14975701)   +5 more
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Characterization of alpha-difluoromethylornithine resistant Leishmania donovaniand its susceptibility to other inhibitors of the polyamine biosynthetic pathway

, 1996
The promastigote form ofLeishmania donovaniis sensitive to growth inhibition by DL -α-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, exhibiting an IC50of 125µM.
Madhubala, R., Kapoor, Preeti, Mukhopadhyay, Rita   +2 more
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α-Difluoromethylornithine reduces gastric carcinogenesis by causing mutations in Helicobacter pylori cagY. [PDF]

Proc Natl Acad Sci U S A, 2019
Sierra JC, Suarez G, Piazuelo MB, Luis PB, Baker DR, Romero-Gallo J, Barry DP, Schneider C, Morgan DR, Peek RM, Gobert AP, Wilson KT.   +11 more
europepmc   +1 more source

Targeting Ornithine Decarboxylase by α-Difluoromethylornithine Inhibits Tumor Growth by Impairing Myeloid-Derived Suppressor Cells. [PDF]

J Immunol, 2016
Ye C, Geng Z, Dominguez D, Chen S, Fan J, Qin L, Long A, Zhang Y, Kuzel TM, Zhang B.   +9 more
europepmc   +1 more source