Results 61 to 70 of about 1,000,648 (145)

Α-Difluoromethylornithine (DFMO) decreases the incidence and size of bone metastases from MDA-MB-435 cells

, 2011
Copyright information:Taken from "Metastasis of hormone-independent breast cancer to lung and bone is decreased by α-difluoromethylornithine treatment"Breast Cancer Research 2005;7(5):R819-R827.Published online 9 Aug 2005PMCID:PMC1242150.Copyright © 2005
Danny R Welch (8425), Douglas J DiGirolamo (71573), Monica M Richert (63671), Andrea Manni (71577), Judith S Bond (71576), Laurence M Demers (71575), Pushkar A Phadke (71571), Gail Matters (71572), Sharlene Washington (71574)   +8 more
core   +1 more source

Insight into the functional and structural relationship of ornithine decarboxylase and its mutants from Lacticaseibacillus rhamnosus

Bulletin of the Korean Chemical Society, Volume 46, Issue 7, Page 730-742, July 2025.
Structural and functional analysis of Lactaseibacillus rhamnosus ODC highlights a key residue influencing PLP binding, enzymatic activity, and crystal structure, providing insight into its catalytic mechanism. Abstract Ornithine decarboxylase (ODC) is a critical enzyme in the polyamine biosynthesis pathway that catalyzes the conversion of l‐ornithine ...
Nonvide Nicolas Adiko, Hyeon Tae Seo, Dae‐Won Ki, Jung Hee Park, Da Som Kim   +4 more
wiley   +1 more source

Α-Difluoromethylornithine (DFMO) (2% per orally in drinking water) decreases polyamine levels in mammary fat pad tumors of MDA-MB-231 cells

, 2011
Copyright information:Taken from "Metastasis of hormone-independent breast cancer to lung and bone is decreased by α-difluoromethylornithine treatment"Breast Cancer Research 2005;7(5):R819-R827.Published online 9 Aug 2005PMCID:PMC1242150.Copyright © 2005
Danny R Welch (8425), Douglas J DiGirolamo (71573), Monica M Richert (63671), Andrea Manni (71577), Judith S Bond (71576), Laurence M Demers (71575), Pushkar A Phadke (71571), Gail Matters (71572), Sharlene Washington (71574)   +8 more
core   +1 more source

Effect on Arabica Coffee Flavor Quality of Enhanced Fermentation With Pichia membranifaciens Through Change Microbial Communities and Chemical Compounds

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
Weissella, Lactococcus, Trichococcus, Leuconostoc, and Massila at the bacterial general level and Pichia, Hanseniaspora, Lachancea, Candida, and Cystofilobasidium at the fungi general level were the predominant microorganisms during the enhanced fermentation of Arabica coffee.
Xiaojing Shen, Qi Wang, Jia Zheng, Xingyu Li, Song Li, Yanhua Yin, Mengli Shang, Kunyi Liu, Wenjuan Yuan, Jilai Zhang   +9 more
wiley   +1 more source

Perspective from Difluoromethylornithine Plus Sulindac for the Prevention of Sporadic Colorectal Adenomas: A Randomized Placebo-Controlled, Double-Blind Trial

, 2008
Perspective from Difluoromethylornithine Plus Sulindac for the Prevention of Sporadic Colorectal Adenomas: A Randomized Placebo-Controlled, Double-Blind ...
John McCracken (382841), Christine E. McLaren (7924316), Frank L. Meyskens (1307922), Steven Goldschmid (15092046), Daniel L. Gillen (11083848), D. Kim Turgeon (15092043), C. Gregory Albers (15092040), Sharon Fujikawa-Brooks (15092034), Eugene W. Gerner (14911290), Michael J. Lawson (12060308), Dennis J. Ahnen (11681805), Daniel Pelot (15092031), Jayashri Kidao (15092037), Gary Kelloff (15026490), Peter Lance (198534), Philip M. Carpenter (14925377), Ernest Hawk (7114970), Curt H. Hagedorn (15092049)   +17 more
core   +1 more source

Α-Difluoromethylornithine (DFMO) treatment decreases lung metastasis of MDA-MB-231 cells

, 2011
Copyright information:Taken from "Metastasis of hormone-independent breast cancer to lung and bone is decreased by α-difluoromethylornithine treatment"Breast Cancer Research 2005;7(5):R819-R827.Published online 9 Aug 2005PMCID:PMC1242150.Copyright © 2005
Danny R Welch (8425), Douglas J DiGirolamo (71573), Monica M Richert (63671), Andrea Manni (71577), Judith S Bond (71576), Laurence M Demers (71575), Pushkar A Phadke (71571), Gail Matters (71572), Sharlene Washington (71574)   +8 more
core   +1 more source

Nanotechnology in brain cancer treatment: The role of gold nanoparticles as therapeutic enhancers

Ibrain, Volume 11, Issue 2, Page 119-145, Summer 2025.
This review highlights the potential of gold nanoparticles (AuNPs) in overcoming the blood‐brain barrier (BBB) to improve brain tumor treatment. By enabling targeted drug delivery and enhancing therapies like radiotherapy, phototherapy, and chemotherapy, AuNPs offer a promising approach for safer, more effective treatments of glioblastoma and other ...
Simona Tarantino, Annalisa Bianco, Valeria De Matteis, Edoardo Scarpa, Rosaria Rinaldi   +4 more
wiley   +1 more source

Biochemical changes associated with α-difluoromethylornithine uptake and resistance in Trypanosoma brucei

, 1987
Procyclic Trypanosoma brucei grown in semi-defined media are sensitive to α-difluoromethylornithine (DFMO) (EC50 100 μM), an inhibitor of ornithine decarboxylase (ODC), a key enzyme in polyamine biosynthesis.
Bellofatto, Vivian, Fairlamb, Alan H.; id_orcid, Henderson, Graeme B., Cross, George A.M.   +3 more
core   +1 more source

Ototoxicity of Long-Term α-Difluoromethylornithine for Skin Cancer Prevention. [PDF]

Laryngoscope, 2023
Chow CL, Havighurst T, Lozar T, Jones TD, Kim K, Bailey HH.   +5 more
europepmc   +1 more source

Polyamines: New Cues in Cellular Signal Transduction

, 2001
The naturally occurring polyamines putrescine, spermidine, and spermine are involved in signal transduction. This has been demonstrated by using inhibitors for polyamine biosynthesis (such as α-difluoromethylornithine) or adding polyamines to cultured ...
Uriel Bachrach, Amalia Tabib, Yong-Chun Wang   +2 more
core   +1 more source