Results 41 to 50 of about 1,000,648 (145)

Microbiota–Neuroinflammation Crosstalk in Primary Brain Tumors: Focus on Glioblastoma

Brain and Behavior, Volume 16, Issue 8, August 2026.
Microbiota–neuroinflammation crosstalk in GBM. The schematic summarizes how gut microbiota and microbiota‐derived signals may influence GBM biology through gut–brain signaling, microbial metabolites, systemic immune modulation, BBB‐related pathways, tumor‐associated microbial signals, and immune‐metabolic changes within the GBM microenvironment.
Tareq Nayef AlRamadneh, Renuka Jyothi S, Priya Priyadarshini Nayak, Anima Nanda, Shaker Al Hasnaawei, Akanksha Bhatt, Ashish Singh Chauhan, Siya Singla, Mehrdad Nourizadeh   +8 more
wiley   +1 more source

Α-Difluoromethylornithine (DFMO) delays orthotopic tumor growth of MDA-MB-231 cells

, 2011
Copyright information:Taken from "Metastasis of hormone-independent breast cancer to lung and bone is decreased by α-difluoromethylornithine treatment"Breast Cancer Research 2005;7(5):R819-R827.Published online 9 Aug 2005PMCID:PMC1242150.Copyright © 2005
Danny R Welch (8425), Douglas J DiGirolamo (71573), Monica M Richert (63671), Andrea Manni (71577), Judith S Bond (71576), Laurence M Demers (71575), Pushkar A Phadke (71571), Gail Matters (71572), Sharlene Washington (71574)   +8 more
core   +1 more source

Interaction Among Microbiota, Chemical Composition, and Quality Variations in Coffea arabica Across Altitudinal Gradients During Wet Processing

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Fermentation significantly altered the dominant bacterial genera from Sphingomonas and Pleomorphomonas (before fermentation) to Weissella and Lactobacillus (after fermentation), while Cladosporium and Fusarium remained the dominant fungal genera. Notably, non‐volatile compounds in de‐pulping coffee beans and volatile compounds of roasted coffee beans ...
Xiaojing Shen, Yamei Wu, Qi Wang, Wenhua Chen, Bintao Peng, Surui Lu, Ying Yang, Kunyi Liu, Jilai Zhang   +8 more
wiley   +1 more source

Salmonella Typhimurium employs spermidine to exert protection against ROS-mediated cytotoxicity and rewires host polyamine metabolism to ameliorate its survival in macrophages

Redox Biology
Salmonella infection entails a cascade of attacks and defence measures. After breaching the intestinal epithelial barrier, Salmonella is phagocytosed by macrophages, where the bacteria encounter multiple stresses, to which it employs relevant ...
Abhilash Vijay Nair, Anmol Singh, R.S. Rajmani, Dipshikha Chakravortty   +3 more
doaj   +1 more source

The Dual Role of the Gut Microbiota in Cancer Chemoresistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi, Aisa Bahar, Meisam Khazaei, Mohammad Reza Arabestani   +3 more
wiley   +1 more source

Effects of polyamines, polyamine precursors, and polyamine biosynthetic inhibitors on somatic embryogenesis from eggplant (Solarium melongena) cotyledons

, 1988
Eggplant (Solarium melongena L.) cotyledons grown on Murashige and Skoog medium with naphthaleneacetic acid formed callus, roots, and somatic embryos. Low levels of naphthaleneacetic acid (0.1 – 0.5 mg L−1) favoored rhizogenesis, intermediate levels (1 ...
Pierre R. Fobert, David T. Webb
core   +1 more source

Dose-Related α-Difluoromethylornithine Ototoxicity [PDF]

, 1991
We assessed the ototoxicity associated with oral alpha-difluoromethylornithine (DFMO) administration in 58 patients with metastatic malignant melanoma.
Meyskens, F L, Croghan, M K, Aickin, Mikel G, Meyskens, Frank L, Croghan, Marilyn K, Aickin, M G   +5 more
core   +1 more source

Hepatocyte growth factor/c‐Met signaling axis in human diseases: Mechanistic insights and therapeutic potential

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Figure 1 visually summarizes the core biological functions and therapeutic potential of the HGF/c‐Met signaling axis. Abstract Hepatocyte growth factor (HGF) is a multifunctional cytokine that activates the tyrosine kinase activity of its specific receptor, c‐Met (mesenchymal–epithelial transition factor).
Hongqin Sun, Hao Shu, Qian Zhang, Jishan Zheng, Yunyan Ma, Dengwang Chen, Jidong Zhang, Tao Song   +7 more
wiley   +1 more source

Inhibition of polyamine biosynthesis in Crithidia fasciculata by d,l-α-difluoromethylornithine and d,l-α-difluoromethylarginine

, 1991
Using Crithidia fasciculata as a model organism for Trypanosoma cruzi, we have examined the effects of d,l-α-difluoromethylornithine (DFMO) and d,l-α-difluoromethylarginine (DFMA) on growth and polyamine synthesis.
Strobos, Carolyn A.M., Hunter, Karl J., Fairlamb, Alan H.; id_orcid   +2 more
core   +1 more source

Chemopreventionof long-term oncological consequences on the model of radiation carcinogenesis in female rats

Сибирский онкологический журнал, 2016
A comparative study of the anticarcinogenic activity of synthetic polyamine inhibitor α-difluoromethylornithine (DFMO) and three plant drugs on the model of radiation carcinogenesis was carried out in 615 female Wistar rats subjected to total body γ ...
V. G. Bespalov, A. V. Alexandrov, A. L. Semenov, E. G. Kovanko, S. D. Ivanov   +4 more
doaj