Familial hypertrophic obstructive cardiomyopathy with the GLA E66Q mutation and zebra body [PDF]
core +1 more source
Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers +16 more
wiley +1 more source
Assessing α-galactosidase OmAGAL2 inhibitors and their impact on germination and sugar profiles in <i>Orobanche minor</i>. [PDF]
Onitsuka M +5 more
europepmc +1 more source
New α-galactosidase-inhibiting aminohydroxycyclopentanes. [PDF]
Weber P +7 more
europepmc +1 more source
ABSTRACT The production of plant‐based meat analogues from various protein sources is an emerging application worldwide, driven by growing population and health concerns. Many microorganisms during fermentation play a crucial role in fermented plant‐based meat alternatives, together with structuring and analytical approaches in terms of nutritional ...
Fatma Beyza Özpınar +4 more
wiley +1 more source
Optimizing α-galactosidase A enzyme cutoff for Fabry disease screening in chronic kidney disease patients: a single-center reassessment of diagnostic yield and cost-effectiveness. [PDF]
Tsai SF, Wu MJ, Hsieh HH, Chen CH.
europepmc +1 more source
Melatonin restores testosterone production in aging Leydig cells by targeting key pathological drivers, particularly oxidative stress and mitochondrial dysfunction. This approach offers a fundamental strategy to reshape the Late‐onset hypogonadism treatment paradigm.
Hui Wu +6 more
wiley +1 more source
Aging‐Driven Immunosuppression: The Role of Tregs in the Ovarian Tumor Microenvironment
In the aged ovarian TME, cancer cells exhibit increased succinate production. Elevated extracellular succinate activates the SUCNR1 receptor on Tregs, promoting their recruitment and contributing to an immunosuppressive environment. This leads to diminished anti‐tumor T cell responses and reduced survival.
Mary P. Udumula +10 more
wiley +1 more source
Silencing of the Alkaline α-Galactosidase Gene <i>CsAGA1</i> Impairs Root and Gall Development in Cucumber upon <i>Meloidogyne incognita</i> Infection. [PDF]
Ji T +5 more
europepmc +1 more source
Telomere shortening occurs with age in the respiratory epithelium, but telomere dysfunction‐induced foci (TIF) accumulate only late in life. In contrast, proteostasis decline emerges earlier and correlates with functional impairment, suggesting it may be a primary driver of cellular senescence during physiological aging.
Céline Coquette +20 more
wiley +1 more source

