Results 211 to 220 of about 57,365 (244)
2′‐FL's Depiction of the Human Physiological Function Landscape
The figure summarizes the multifaceted physiological effects of 2′‐fucosyllactose (2′‐FL), a major human milk oligosaccharide. The schematic illustrates the central role of the gut‐centered regulatory axis, where 2′‐FL modulates gut microbiota composition, promotes the production of short‐chain fatty acids and microbial metabolites, enhances mucus ...
Yushan Xiao +3 more
wiley +1 more source
Phillyrin (PHI), a dietary bioactive lignan isolated from Forsythia suspensa, alleviates D‐galactose‐induced cognitive impairment by suppressing the TLR4/NF‐κB signaling pathway. PHI inhibits TLR4‐mediated activation of NF‐κB, thereby reducing neuroinflammation and oxidative stress, preserving neuronal structure and synaptic plasticity, and ultimately ...
Xuemin Li +9 more
wiley +1 more source
In cardiac cells, Plin5/AMPK regulate lipid homeostasis; excess CD36‐mediated uptake drives lipotoxicity, mitochondrial dysfunction, and CVDs (e.g., heart failure). Biomarkers (ApoB/ApoA‐1) and therapies (SGLT2 inhibitors) target this cascade. ABSTRACT Cardiac lipid metabolism is fundamental to myocardial energy homeostasis, with fatty acid oxidation ...
Peiyun Xie +3 more
wiley +1 more source
ABSTRACT Background Dnajb5, a member of the heat shock protein family, has not been previously reported to play a role in muscle differentiation. We identify Dnajb5 as a negative regulator of myogenesis via mammalian target of rapamycin (mTOR) and histone deacetylase 4 (HDAC4) signalling, functioning as a central controller of muscle growth and ...
Sun‐Hee Cho +8 more
wiley +1 more source
Neutrophils acquire extracellular fatty acids or adipocyte‐derived lipids and store them as triglycerides, polarizing into a lipid‐laden phenotype. Lipid‐laden neutrophils are found in the peripheral blood of HFD‐fed mice and patients with MASLD. These neutrophils release extracellular vesicles enriched with triglycerides and microRNAs that deliver ...
Sanjeeb Shrestha +10 more
wiley +1 more source
Integrated microbiological, genomic, and structural analyses of bacteria isolated from a Peruvian geothermal system reveal enzymatic potential for the transformation of polyesters such as PET. This study links experimental evidence with genomic determinants and in silico analyses that support the thermophilic bacteria biodegradation capacity.
Marco A. Rivera‐Jacinto +6 more
wiley +1 more source
Starvation stress significantly affected the growth and development of Hippodamia variegata. Combined transcriptome and metabolome analysis and RNA interference verification revealed that HvarAKR1B1 may be involved in the response of Hippodamia variegata to starvation stress.
Bing‐mei Song +5 more
wiley +1 more source
ABSTRACT The healing of diabetic chronic wounds is hindered by multiple pathological barriers, including oxidative stress imbalance induced by hyperglycemia, persistent bacterial infection, and impaired neovascular function. This study developed an F127–HA–BiOCl@CeO2 (FHBC) hydrogel dressing with acoustic responsiveness, achieving tissue repair through
Ran Zhao +8 more
wiley +1 more source
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Acta Horticulturae, 2005
Different sour cherry cultivars (cv. 'Erdi botermo', 'Kantorjanosi' and 'Pandy 279') were harvested than stored for 30 days at 4-6°C, 89-90% RH. The absorbance pattern of juice was different between fresh and stored fruits, especially in case of cv. 'Kantorjanosi'. No remarkable differences was found in cv. 'Erdi botermo' fresh and stored.
E. Kovács +2 more
openaire +1 more source
Different sour cherry cultivars (cv. 'Erdi botermo', 'Kantorjanosi' and 'Pandy 279') were harvested than stored for 30 days at 4-6°C, 89-90% RH. The absorbance pattern of juice was different between fresh and stored fruits, especially in case of cv. 'Kantorjanosi'. No remarkable differences was found in cv. 'Erdi botermo' fresh and stored.
E. Kovács +2 more
openaire +1 more source

