Results 11 to 20 of about 2,753,652 (191)
Marine Drugs, 2011 Bis(2,3-dibromo-4,5-dihydroxybenzyl) ether (BDDE), derived from the marine algae, is a potential α-glucosidase inhibitor for type 2 diabetes treatment.
Xiukun Lin +3 more
doaj +2 more sources
Evolution of the α‐Glucosidase Gene Family in Apoidea [PDF]
Ecology and EvolutionWith more than 20,000 recognized species, the Apoidea is one of the most significant groups of pollinating insects, and their living environment is complex and diverse.
Jiaqi Li +4 more
doaj +2 more sources
Serum α-Glucosidase Activity as a New Parameter of Negative Energy Balance in Dairy Cows [PDF]
Veterinary SciencesEnzymes of the α-glucosidase group cleave α-D-glucose from the non-reducing end of short oligosaccharides. They contribute to carbohydrate digestion as maltase-glucoamylase in the intestinal brush border and as neutral α-glucosidase in other tissues ...
Babett Bartling +3 more
doaj +2 more sources
Flavonoids as dual-target inhibitors against α-glucosidase and α-amylase: a systematic review of in vitro studies [PDF]
, 2023 Diabetes mellitus remains a major global health burden and great attention is directed at natural therapeutics. This systematic review aimed to evaluate the potential of flavonoids as antidiabetic agents through their ability to inhibit α-amylase and α ...
Ngoc-Vi Nguyen, Tran +9 more
core +2 more sources
In vitro α-glucosidase inhibitory activity of Tamarix nilotica shoot extracts and fractions.
PLoS ONE, 2022 α-glucosidase inhibitors represent an important class of type 2 antidiabetic drugs and they act by lowering postprandial hyperglycemia. Today, only three synthetic inhibitors exist on the market, and there is a need for novel, natural and more efficient ...
Mariane Daou +5 more
doaj +2 more sources
Inhibitory Mechanism of Engeletin Against α-Glucosidase
Natural Product Communications, 2021 The inhibitory mechanism of engeletin against α-glucosidase was investigated for the first time by fluorescence spectroscopy and molecular docking. The results showed that engeletin could inhibit α-glucosidase in a noncompetitive inhibition mode with a ...
Yunbo Li +4 more
doaj +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 Different oleanolic acid (OA) oxime ester derivatives (3a-3t) were designed and synthesised to develop inhibitors against α-glucosidase and α-amylase. All the synthesised OA derivatives were evaluated against α-glucosidase and α-amylase in vitro.
Xu-Yang Deng +9 more
doaj +1 more source
Inhibitory Activity and Mechanism Investigation of Hypericin as a Novel α-Glucosidase Inhibitor
Molecules, 2021 α-glucosidase is a major enzyme that is involved in starch digestion and type 2 diabetes mellitus. In this study, the inhibition of hypericin by α-glucosidase and its mechanism were firstly investigated using enzyme kinetics analysis, real-time ...
Qi Dong, Na Hu, Huilan Yue, Honglun Wang
doaj +1 more source
Foods, 2023 In recent years, food-derived hypoglycemic peptides have received a lot of attention in the study of active peptides, but their anti-diabetic mechanism of action is not yet clear.
Yuanping Zhang +4 more
semanticscholar +1 more source
Cafestol analogues from Coffea canephora: in vitro inhibition and molecular docking to α-glucosidase
, 2022 A new cafestol-type diterpenoid, 5β-hydroxy-2-oxocafestol named coffecanepholide C (1) along with three known diterpenoids including cafestol (2), tricalysiolide A (3) and atractyligenin (4) were identified from the Coffea canephora trunks collected at ...
Thi Anh Tuyet Nguyen (9558826) +3 more
core +1 more source