Results 21 to 30 of about 2,753,652 (191)
Dietary Polyphenols as Natural Inhibitors of α-Amylase and α-Glucosidase
Life, 2022 It is well known that carbohydrates are the main source of calories in most diets. However, by inhibiting carbohydrases, intake of calories is reduced and weight loss is improved.
Ina Ćorković +4 more
semanticscholar +1 more source
, 2021 Four flavonoid glycosides containing coumaroyl or feruloyl groups were isolated from the male flowers of Ginkgo biloba L., and compounds 3 and 4 were identified as novel compounds.
Wei-Dong Zhu (1478668) +4 more
core +1 more source
Carnitine is a pharmacological allosteric chaperone of the human lysosomal α-glucosidase
, 2022 Pompe disease is an inherited metabolic disorder due to the deficiency of the lysosomal acid α-glucosidase (GAA). The only approved treatment is enzyme replacement therapy with the recombinant enzyme (rhGAA).
Roberta Iacono (4610482) +12 more
core +1 more source
Molecules, 2023 To find potential α-glucosidase inhibitors, indolo[1,2-b]isoquinoline derivatives (1–20) were screened for their α-glucosidase inhibitory effects. All derivatives presented potential α-glucosidase inhibitory effects with IC50 values of 3.44 ± 0.36~41.24 ±
Mengyue Li +5 more
doaj +1 more source
International Journal of Molecular Sciences, 2023 Controlling post-prandial hyperglycemia and hyperlipidemia, particularly by regulating the activity of digestive enzymes, allows managing type 2 diabetes and obesity.
Quentin Haguet +11 more
semanticscholar +1 more source
ACS Omega, 2023 There is an increasing prevalence of diabetes mellitus throughout the world, and new compounds are necessary to combat this. The currently available antidiabetic therapies are long-term complicated and side effect-prone, and this has led to a demand for ...
Imran Khan +8 more
semanticscholar +1 more source
Frontiers in Chemistry, 2022 α-Glucosidase inhibitors are known to prevent the digestion of carbohydrates and reduce the impact of carbohydrates on blood glucose. To develop novel α-glucosidase inhibitors, a series of 5-fluoro-2-oxindole derivatives (3a ∼ 3v) were synthesized, and ...
Jing Lin +10 more
doaj +1 more source
, 2023 Phytochemical investigation on the bark of E. kingiana plant afforded ten compounds, including six polyketides namely kingianin A 1, kingianin B 2, kingianin E 3, kingianin F 4, kingianin K 5 and kingianin L 6, three endiandric acids; kingianic acid A 7,
Mohamad Hafizi Abu Bakar (10528601) +9 more
core +1 more source
Bangladesh Journal of Pharmacology, 2013 In this study, the effect of ethanol extract of the leaves of Newbouldia laevis on the activity of α-amylase and α-glucosidase was investigated. Inhibitory effect of N. laevis extract on α-glucosidase was tested in vitro using baker's yeast α-glucosidase
Oyetunji T. Kolawole, Musbau A. Akanji
doaj +1 more source
Food Chemistry, 2021 Phenolic acids are involved in modulating the activity of starch digestive enzymes but remains unclear if their interaction with enzymes or starch is governing the inhibition.
Andrea Aleixandre +3 more
semanticscholar +1 more source