Results 31 to 40 of about 2,753,652 (191)
Current antidiabetic drugs have severe side effects, which may be minimized by new selective molecules that strongly inhibit α-glucosidase and weakly inhibit α-amylase.
Dolores G. Aguila-Muñoz +10 more
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Docking Sulochrin and Its Derivative as α-Glucosidase Inhibitors of Saccharomyces cerevisiae
Sulochrin known has activity as inhibitors of α-glucosidase enzyme. Interaction of sulochrin to active site of α-glucosidase enzyme from S. cerevisiae has studied by docking method.
Wening Lestari +3 more
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Synthesis and Evaluation of Coumarin-Chalcone Derivatives as α-Glucosidase Inhibitors
Coumarin and chalcone, two important kinds of natural product skeletons, both exhibit α-glucosidase inhibitory activity. In this work, coumarin-chalcone derivatives 3 (a∼v) were synthesized, and their α-glucosidase inhibitory activity was screened.
Chun-Mei Hu +10 more
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In vitro α-amylase and α-glucosidase inhibitory potential of Pleurotus ostreatus cv. Florida extract [PDF]
1016-1019Pleurotus ostreatus cv. Florida is one of the widely used edible mushroom. The polysaccharides from this mushrooms have been studied for antidiabetic potential; however, no efforts have been made to explore the potential of this mushroom to ...
Chourasia, Ayushi +5 more
core +1 more source
Inhibitory Kinetics of Cyanidin-3-O-glucoside against α-Amylase and α-Glucosidase [PDF]
The inhibitory mechanism of α-amylase and α-glucosidase by cyanidin-3-O-glucoside was investigated by ultrafiltration, high performance liquid chromatography (HPLC), enzyme kinetics, and molecular docking.
WANG Wei, CUI Yan, ZHENG Mingzhu, CAI Dan, LIU Jingsheng, LIU Meihong, LIU Huimin
core +2 more sources
Interaction of sulochrin to active site of glucosidase enzyme of Termotoga maritime has been studied by employing docking method using Molecular Operating Environment (MOE), in comparison with those are reports of established inhibitor α-glucosidase such
Rizna Triana Dewi +4 more
doaj +1 more source
Two new fatty acid derivatives identified as 5,7-dihydroxy-6-oxoheptadecanoic acid (1) and ethyl-5,7-dihydroxy-6-oxooctadecanoate (2) together with four known compounds, ethyl linolenate (3), ethyl linoleate (4), ethyl pheophorbide A (5), and ...
Makinde, Emmanuel Ayobami +4 more
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Clausena indica (Datz.) Oliv fruit pericarps (CIOPs) is an important agro-industrial by-product rich in active components. In this article, the effects of traditional and green deep eutectic solvents (DESs) on the high-performance liquid chromatography ...
Zhaohui Li (442068) +3 more
core +1 more source
A method for in vivo evaluation of α-glucosidase inhibition using Drosophila
The development of α-glucosidase inhibitors is essential for the prevention of type II diabetes. Previous research has investigated in vitro inhibition using isolated α-glucosidase, which may not accurately reflect physical processes.
Nattapong Wongchum +4 more
doaj +1 more source
The α-glucosidase inhibitor is of interest to researchers due to its association with type-II diabetes treatment by suppressing postprandial hyperglycemia. Hesperidin is a major flavonoid in orange fruit with diverse biological properties.
Kumaravel Kaliaperumal +6 more
doaj +1 more source

