Results 41 to 50 of about 2,753,652 (191)

The α-Amylase and α-Glucosidase Inhibition Capacity of Grape Pomace: A Review

open access: yesFood and Bioprocess Technology, 2022
The concept of functional foods is gaining more importance due to its role in maintaining a healthy status and preventing some metabolic diseases. The control of diabetes, in particular type-2 (T2DM), could be considered a big challenge since it involves
Miluska Cisneros‐Yupanqui   +4 more
semanticscholar   +1 more source

Image_1_LC-Q-Orbitrap-MS/MS Characterization, Antioxidant Activity, and α-Glucosidase-Inhibiting Activity With In Silico Analysis of Extract From Clausena Indica (Datz.) Oliv Fruit Pericarps.JPEG

open access: yes, 2021
Clausena indica (Datz.) Oliv fruit pericarps (CIOPs) is an important agro-industrial by-product rich in active components. In this article, the effects of traditional and green deep eutectic solvents (DESs) on the high-performance liquid chromatography ...
Zhaohui Li (442068)   +3 more
core   +1 more source

An overview on the role of bioactive α-glucosidase inhibitors in ameliorating diabetic complications

open access: yesFood and Chemical Toxicology, 2020
Recently the use of bioactive α-glucosidase inhibitors for the treatment of diabetes have been proven to be the most efficient remedy for controlling postprandial hyperglycemia and its detrimental physiological complications, especially in type 2 ...
Uday Hossain   +3 more
semanticscholar   +1 more source

Intestinal α-Glucosidase Inhibitors in Achillea millefolium [PDF]

open access: yes, 2017
Achillea millefolium is a plant used as a component of anti-diabetic preparation but the bioactive compounds responsible for its use are not known. Inhibition of intestinal α-glucosidase is a preferable effect for prevention and treatment of diabetes ...
Kato, Eisuke, Noda, Kota, Kawabata, Jun
core   +1 more source

Design, Synthesis, In Silico Testing, and In Vitro Evaluation of Thiazolidinone-Based Benzothiazole Derivatives as Inhibitors of α-Amylase and α-Glucosidase

open access: yesPharmaceuticals, 2022
In this study, a stepwise reaction afforded thiazolidinone-based benzothiazole derivatives 1–15, and the synthesized derivatives were then screened for biological significance and found to be the leading candidates against α-amylase and α-glucosidase ...
Shoaib Khan   +11 more
semanticscholar   +1 more source

α-/β-Glucosidase and α-Amylase Inhibitory Activities of Roselle (Hibiscus sabdariffa L.) Ethanol Extract [PDF]

open access: yes, 2017
Background: Diabetes mellitus is a metabolic disease, characterized by hyperglycemia due to disturbance in both insulin secretion and function. One of theurapeutic approaches is to reduce blood glucose levels by inhbiting α-/β-glucosidase and α-amylase ...
Wahyu Widowati   +5 more
core   +1 more source

Flavonoids as dual-target inhibitors against α-glucosidase and α-amylase: a systematic review of in vitro studies

open access: yesNatural Products and Bioprospecting
Diabetes mellitus remains a major global health issue, and great attention is directed at natural therapeutics. This systematic review aimed to assess the potential of flavonoids as antidiabetic agents by investigating their inhibitory effects on α ...
Thua-Phong Lam   +9 more
semanticscholar   +1 more source

Inhibitors of α‐amylase and α‐glucosidase: Potential linkage for whole cereal foods on prevention of hyperglycemia

open access: yesFood Science & Nutrition, 2020
The strategy of reducing carbohydrate digestibility by controlling the activity of two hydrolyzing enzymes (α‐amylase and α‐glucosidase) to control postprandial hyperglycemia is considered as a viable prophylactic treatment of type 2 diabetes mellitus ...
Ling-Xiao Gong   +5 more
semanticscholar   +1 more source

In Silico Approaches to Identify Polyphenol Compounds as α-Glucosidase and α-Amylase Inhibitors against Type-II Diabetes

open access: yesBiomolecules, 2021
Type-II diabetes mellitus (T2DM) results from a combination of genetic and lifestyle factors, and the prevalence of T2DM is increasing worldwide. Clinically, both α-glucosidase and α-amylase enzymes inhibitors can suppress peaks of postprandial glucose ...
Jirawat Riyaphan   +3 more
semanticscholar   +1 more source

Pentacylic triterpenes from Lavandula coronopifolia: structure related inhibitory activity on α-glucosidase

open access: yes, 2019
Ten pentacyclic triterpenes (1-10) were isolated from Lavandula coronopifolia. We evaluated their α-glucosidase inhibitory activity, and found that the aglycones, 1, 2, 3, 4, 7 and 10 showed superior IC50 values to the positive control.
Rogers Mwakalukwa (7297793)   +3 more
core   +1 more source

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