Results 71 to 80 of about 1,551,967 (375)

Fluorinated indeno-quinoxaline bearing thiazole moieties as hypoglycaemic agents targeting α-amylase, and α-glucosidase: synthesis, molecular docking, and ADMET studies

Journal of Enzyme Inhibition and Medicinal Chemistry
Inhibition of α-glucosidase and α-amylase are key tactics for managing blood glucose levels. Currently, stronger, and more accessible inhibitors are needed to treat diabetes.
Nirvana A. Gohar, Eman A. Fayed, Yousry A. Ammar, Ola A Abu Ali, A. Ragab, Amal M Mahfoz, Moustafa S. Abusaif   +6 more
semanticscholar   +1 more source

Antioxidant and Anti-α-Glucosidase Activities of Various Solvent Extracts and Major Bioactive Components from the Fruits of Crataegus pinnatifida

Antioxidants, 2022
Crataegus pinnatifida is used to treat various diseases, including indigestion, congestive heart failure, hypertension, atherosclerosis, and myocardial dysfunction.
Yen-Ting Lin, Hsiang-Ru Lin, Chang-Syun Yang, Chia-Ching Liaw, P. Sung, Y. Kuo, M. Cheng, Jih-Jung Chen   +7 more
semanticscholar   +1 more source

Honokiol as an α-glucosidase inhibitor

Frontiers in Pharmacology
Honokiol, a naturally occurring compound from Magnolia obovata Thunb., has many biological activities, but its anti-α-glucosidase activity is still unclear. Therefore, we determined its inhibitory effects against α-glucosidase.
Hua Zhu, Xin Zhong
doaj   +1 more source

In Vitro α-Glucosidase Inhibitory Activity of Ethanol Extract of Buas-buas (Premna Serratifolia Linn) [PDF]

, 2017
In 2008, diabetics in Indonesia has reached 8,5 million of 11,1 % prevalence in West Kalimantan. It was estimated to reach 14,1 million in 2035. The treatment of diabetes may occur adverse reactions such as hypoglycemia, lipoatrophy, lipohypertrophy ...
Hadiarti, D. (Dini)
core   +3 more sources

Comparison of Various Solvent Extracts and Major Bioactive Components from Portulaca oleracea for Antioxidant, Anti-Tyrosinase, and Anti-α-Glucosidase Activities

Antioxidants, 2022
Portulaca oleracea is a well-known species for traditional medicine and food homology in Taiwan. In traditional medicine, P. oleracea is also used to treat gastrointestinal disorders, liver inflammation, fever, severe inflammation, and headaches.
Wei‐Cheng Chen, Shih-Wei Wang, Cai-Wei Li, Hsiang-Ru Lin, Chang-Syun Yang, Yi-Cheng Chu, Tzong-Huei Lee, Jih-Jung Chen   +7 more
semanticscholar   +1 more source

A review on α-glucosidase inhibitory activity of first row transition metal complexes: a futuristic strategy for treatment of type 2 diabetes

RSC Advances, 2022
Type 2 diabetes mellitus (T2DM) is characterized by high blood glucose levels and has emerged as a controversial public health issue worldwide. The increasing number of patients with T2DM on one hand, and serious long-term complications of the disease ...
M. Sohrabi, M. Binaeizadeh, Aida Iraji, B. Larijani, Mina Saeedi, M. Mahdavi   +5 more
semanticscholar   +1 more source

Effect of different drying treatments and solvent ratios on phytochemical constituents of Ipomoea aquatica and correlation with α-Glucosidase inhibitory activity [PDF]

, 2016
Ipomoea aquatica is an aquatic plant that is widely consumed in Southeast Asia as a vegetable. In this study, the influence of various ethanol ratios (0, 20, 50, 80, and 100%) as an extraction solvent and different drying methods including air drying ...
Abas, Faridah, Abu Bakar Sajak, Azliana, Ismail, Amin, Khatib, Alfi   +3 more
core   +1 more source

Bioaffinity ultrafiltration coupled with HPLC-ESI-MS/MS for screening potential α-glucosidase inhibitors from pomegranate peel

Frontiers in Nutrition, 2022
Pomegranate peel (PoP) contains plenty of bioactive compounds and exhibits strong activity to prevent postprandial hyperglycaemia and improve diabetes mellitus.
Rujie Shi, Nong Zhou, Han Zhang, Min Gong, Lin Han, Lin Han   +5 more
doaj   +1 more source

Properties and stabilization of an extracellular α-glucosidase from the extremely thermophilic archaebacteria Thermococcus strain AN 1: enzyme activity at 130°C [PDF]

, 1996
An extracellular α-glucosidase from the thermophilic archaebacterium Thermococcus strain AN1 was purified 875-fold in five steps (Hiload Q-Sepharose, phenyl Sepharose, HPHT-hydroxyapatite, gel filtration and Mono Q chromatography) with a yield of 4%.
Daniel, Roy M., Petach, Helen H., Piller, Karin   +2 more
core   +2 more sources

Enhancing and Stabilizing Hydrogen Catalysis Through [NiFe]‐Hydrogenase Immobilization Within Macroporous Covalent Organic Frameworks

Advanced Functional Materials, EarlyView.
[NiFe]‐hydrogenases efficiently catalyze hydrogen conversion, but their instability limits biotechnological applications. Here it is shown that encapsulating hydrogenase into hierarchical COFs with macro‐ and micropores and functionalized with sulfonic or carboxylic acid groups improves enzyme stability and electron transfer to electrodes.
Islam E. Khalil, Armel F. Tadjoung Waffo, Prasenjit Das, Sagie Katz, Sandra Kunow, Christian Lorent, Yasmine Ziouani, Warisha Tahir, Augustine A. Owusu, Oliver Lenz, Ingo Zebger, Stefan Frielingsdorf, Arne Thomas   +12 more
wiley   +1 more source