Results 111 to 120 of about 33,378 (259)

Comparison of cardiovascular outcomes between once‐weekly semaglutide and dulaglutide in adults with type 2 diabetes and established atherosclerotic cardiovascular disease in the United States

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims This study aims to compare the risk of major adverse cardiovascular events (MACE) among United States individuals with type 2 diabetes (T2D) and atherosclerotic cardiovascular disease (ASCVD) treated with once‐weekly semaglutide vs. dulaglutide.
Xi Tan, Yuanjie Liang, Lin Xie, Joanna Harton, Cynthia Gutierrez, Chalak Muhammad, Caroline Swift, Adam de Havenon   +7 more
wiley   +1 more source

Risk of acute pancreatitis with DPP‐4 inhibitors versus SGLT2 inhibitors in medication‐naïve individuals with diabetes: A target trial emulation

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims We investigated whether dipeptidyl peptidase‐4 inhibitor (DPP‐4i) use was associated with a higher risk of acute pancreatitis compared with sodium–glucose cotransporter 2 inhibitor (SGLT2i) use in antidiabetic medication‐naïve individuals.
Takashi Tatewaki, Akira Okada, Yuya Kimura, Hideo Yasunaga   +3 more
wiley   +1 more source

Inhibition of α-glucosidase by melatonin derivatives: insights from kinetics, docking, and molecular dynamics simulations

Medicine in Drug Discovery
Type 2 diabetes mellitus (T2DM) represents a major global health challenge, emphasizing the need for effective strategies to manage postprandial hyperglycemia.
Ploenthip Puthongking, Bodee Nutho, Muhammad Subhan, Juthamat Ratha, Kiattawee Choowongkomon, Saranyu Khammuang, Kamonpan Sanachai   +6 more
doaj   +1 more source

Bio-Oriented Synthesis of Novel Polyhydroquinoline Derivatives as α-Glucosidase Inhibitor for Management of Diabetes. [PDF]

ACS Omega, 2023
Talab F, Ullah S, Alam A, Halim SA, Rehman NU, Zainab, Ali M, Latif A, Khan A, Al-Harrasi A, Ahmad M.   +10 more
europepmc   +1 more source

Reinventing henna: Enzyme‐catalysed colour release from stabilized Lawsonia inermis L. extracts

International Journal of Cosmetic Science, EarlyView.
The instability and reduced dyeing performance of a cosmetic formulation containing 2‐hydroxy‐1,4‐naphthoquinone (lawsone), derived from Lawsonia inermis L., is demonstrated in comparison to a novel two‐component system. This system comprises one formulation with naturally occurring lawsone precursors and a second containing a specific hydrolase ...
Nele Dallmann, Volkmar Vill, Fabian Straske   +2 more
wiley   +1 more source

Phytochemical constituent, α-amylase and α-glucosidase inhibitory activities of Black Soybean (Glycine soja (L.) Merr.) ethanol extract

Pharmaciana
Diabetes is characterized as a hyperglycemic condition impacted by β-cell dysfunction and insulin deficiency. Black soybean (Glycine soja (L.) Merr.) is widely known as an origin of nutritious food that has shown activities in preventing cardiovascular ...
Afifah Bambang Sutjiatmo, Suci Narvikasari, Ananda Khairunisa Solihat, Wahyu Widowati, Hanna Sari Widya Kusuma, Fadhilah Haifa Zahiroh   +5 more
doaj   +1 more source

Combined Dipeptidyl Peptidase 4 Inhibitor and α-Glucosidase Inhibitor Treatment in Postprandial Hypoglycemia. [PDF]

Clin Diabetes, 2022
Broome DT, Kodali A, Phillips D, Makin V, Mendlovic D, Zimmerman RS.   +5 more
europepmc   +1 more source

Therapeutic potentials of black tea medicaments [PDF]

, 2014
Tea; a product of Camellia Sinensis plant is the most broadly used beverage in the world. Tea phytochemicals have been studied for the prevention of various chronic diseases, such as cancer, obesity, diabetes, jaundice, hypertension and inflammation ...
Mohapatra, S
core  

Linderalactone mitigates diabetic renal injury by inhibiting macrophage inflammation via the Dectin1/Syk/CARD9/IRF5/NF‐κB pathway

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background Inflammation plays an essential role in the pathogenesis of diabetic nephropathy (DN). Linderalactone (LNL), as a natural sesquiterpene lactone, has been discovered to have anti‐inflammatory activation. However, the effects of linderalactone on diabetes‐associated renal damage remain unclear.
Hao Chen, Sheng Xu, Bingrong Chen, Xishan Xiong, Jinrui Hu, Yuhong Wu, Tianrui Wang, Huishang Wang   +7 more
wiley   +1 more source

Synthesis, Molecular Docking, and Bioactivity Study of Novel Hybrid Benzimidazole Urea Derivatives: A Promising α-Amylase and α-Glucosidase Inhibitor Candidate with Antioxidant Activity. [PDF]

Pharmaceutics, 2023
Aroua LM, Alosaimi AH, Alminderej FM, Messaoudi S, Mohammed HA, Almahmoud SA, Chigurupati S, Albadri AEAE, Mekni NH.   +8 more
europepmc   +1 more source