Results 121 to 130 of about 33,464 (260)

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Exploring the inhibitory effect and mechanism of 3,4,5-trihydroxybiphenyl on α-glucosidase: an integrated experimental and computational approach

Frontiers in Pharmacology
3,4,5-Trihydroxybiphenyl (THB) is a naturally occurring compound derived from Sorbus pohuashanensis, primarily reported for its antifungal activity. However, its potential to inhibit α-glucosidase remains unclear.
Ruofan Guo, Ruofan Guo, Guohua Yu, Yuan Li, Youyou Wang, Youyou Wang, Huixia Fan, Shuo Zhang, Chen Wang, Junhui Zhou, Junhui Zhou, Jian Yang, Jian Yang, Feng Gao, Feng Gao, Zhiqiang Luo   +15 more
doaj   +1 more source

Personal Glucose Meter for α-Glucosidase Inhibitor Screening Based on the Hydrolysis of Maltose. [PDF]

Molecules, 2021
Tian T, Chen GY, Zhang H, Yang FQ.
europepmc   +1 more source

Acarbose or Canagliflozin vs. Placebo to Ameliorate Post‐Bariatric Hypoglycaemia: The Clinical Outcomes of the HypoBar I Randomised Clinical Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Treatment options for post‐bariatric hypoglycaemia (PBH) are empirical. We aimed to investigate the efficacy and safety of acarbose and canagliflozin for the treatment of PBH. Materials and Methods We performed a randomised, double‐blinded, cross‐over, placebo‐controlled clinical trial where placebo, acarbose 50 mg thrice daily, and ...
Carolina B. Lobato, Clara Tornøe Winding, Kirstine N. Bojsen‐Møller, Bolette Hartmann, Christoffer Martinussen, Simon Veedfald, Jens J. Holst, Sten Madsbad, Nils Bruun Jørgensen, Carsten Dirksen   +9 more
wiley   +1 more source

In vitro study on the hypoglycemic potential of Nicotiana tabacum leaf extracts

Bangladesh Journal of Pharmacology, 2014
Inhibition of some carbohydrate metabolizing enzymes is one of the modes of action of antihyperglycemic agents. The aim of this study was to investigate the in vitro inhibition of α-amylase and α-glucosidase by extracts of N. tabacum leaf.
Mutiu Idowu Kazeem, Semawon Mauton Ogungbe, Gbemisola Morounke Saibu, Oluwaseyi Mayode Aboyade   +3 more
doaj  

Optimization of Extraction Process of Polysaccharides MAP-2 from Opuntia Milpa Alta by Response Surface Methodology and Evaluation of Its Potential as α-Glucosidase Inhibitor. [PDF]

Foods, 2022
Yang Y, Yang M, Zhou X, Chen H.
europepmc   +1 more source

Comparison of SGLT2 Inhibitors for New‐Onset Proteinuria Risk in Patients With Type 2 Diabetes and Preserved Kidney Function

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To compare the effects of individual SGLT2 inhibitors on preventing new‐onset proteinuria in patients with type 2 diabetes and preserved kidney function. Materials and Methods A target trial emulation was performed using commercially available databases, including health checkups and claims data, between April 1, 2014 and March 31, 2023 ...
Hiroki Nobayashi, Michihiro Satoh, Takuo Hirose, Shingo Nakayama, Yutaro Iwabe, Hideaki Hashimoto, Takahisa Murakami, Kouji Okada, Takefumi Mori, Hirohito Metoki   +9 more
wiley   +1 more source

A review on the in vitro and in vivo screening of α-glucosidase inhibitors

Heliyon
As a global metabolic disease, the control and treatment of diabetes have always been the focus of medical research. α-Glucosidase is a key enzyme in regulating blood glucose levels and has important applications in the treatment of diabetes. This review
Guangjuan Pan, Yantong Lu, Zhiying Wei, Yaohua Li, Li Li, Xiaojiao Pan   +5 more
doaj   +1 more source

Bioaccessibility of provitamin A carotenoids in orange-fleshed pumpkins using the coupled In vitro digestion/ Caco-2 cell model. [PDF]

, 2016
The aim of this study was to evaluate the effects of cooking styles on the bioacessibility of BC in ...
CARVALHO, J. L. V. de, CARVALHO, L. M. J. de, CHITCHUMROONCHOKCHAI, C., FAILLA, M. L., RIBEIRO, E. M. G.   +4 more
core  

Sex‐Specific Associations of Inflammatory Biomarkers With All‐Cause and Cardiovascular Mortality Across Glycaemic Status: A Prospective UK Biobank Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang, Menghan Li, Manrong Xu, Yun Shen, Lianxi Li, Gang Hu   +5 more
wiley   +1 more source