Results 11 to 20 of about 33,378 (259)

Inhibition of Digestive Enzymes and Antioxidant Activity of Extracts from Fruits of Cornus alba, Cornus sanguinea subsp. hungarica and Cornus florida - A Comparative Study [PDF]

, 2020
The fruits of some Cornus species (dogwoods) are used in traditional medicine and considered potential anti-diabetic and hypolipemic agents. The aim of the study was to determine the ability of extracts from Cornus alba (CA), Cornus florida (CF), and ...
Buchholz, Tina, Czerwińska, Monika E., Melzig, Matthias F., Stanisławska, Iwona, Truba, Joanna, Walasek, Marta, Wieczorkowska, Wioleta, Woliński, Konrad   +7 more
core   +1 more source

Design, synthesis, in vitro, and in silico evaluations of benzo[d]imidazole-amide-1,2,3-triazole-N-arylacetamide hybrids as new antidiabetic agents targeting α-glucosidase

Scientific Reports, 2023
α-Glucosidase as a carbohydrate-hydrolase enzyme is a crucial therapeutic target for type 2 diabetes. In this work, benzo[d]imidazole-amide containing 1,2,3-triazole-N-arylacetamide derivatives 8a–n were synthesized and evaluated for their inhibitory ...
Faeze Yousefnejad, Mahyar Mohammadi-Moghadam-Goozali, Mohammad Hosein Sayahi, Mohammad Halimi, Ali Moazzam, Maryam Mohammadi-Khanaposhtani, Somayeh Mojtabavi, Mehdi Asadi, Mohammad Ali Faramarzi, Bagher Larijani, Massoud Amanlou, Mohammad Mahdavi   +11 more
doaj   +1 more source

α-Glucosidase Inhibitory Activity of Fermented Okara Broth Started with the Strain Bacillus amyloliquefaciens SY07

Molecules, 2022
In this work, a new strain of Bacillus amyloliquefaciens SY07 isolated from a traditional fermented soybean food was reported to possess remarkable α-glucosidase inhibitor-producing ability. Different culture media were applied for the proliferation of B.
Yifang Gao, Wenhui Bian, Yuanyuan Fang, Peng Du, Xueting Liu, Xueru Zhao, Fengjuan Li   +6 more
doaj   +1 more source

Inhibitory Kinetics of Cyanidin-3-O-glucoside against α-Amylase and α-Glucosidase [PDF]

Shipin Kexue, 2023
The inhibitory mechanism of α-amylase and α-glucosidase by cyanidin-3-O-glucoside was investigated by ultrafiltration, high performance liquid chromatography (HPLC), enzyme kinetics, and molecular docking.
WANG Wei, CUI Yan, ZHENG Mingzhu, CAI Dan, LIU Jingsheng, LIU Meihong, LIU Huimin
doaj   +1 more source

FLAVONOIDS FROM RHYNCHOSIA PSEUDO-CAJAN AS SUITABLE α-GLUCOSIDASE INHIBITORS AND FREE RADICAL SCAVENGERS

International Research Journal of Pharmacy, 2014
A series of nine flavonoids , 1 - 9, isolated from Rhynchosia pseudo - cajan Cambe ss., ha s been investigated in present work for their biological potential against α - glucosidase, lipoxygenase (LOX), acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes ; and antioxidant activity against diphenylpicrylhydrazyl (DPPH) radica l ...
Muhammad Athar Abbasi, Ghulam Hussain, Aziz ur Rehman, Viqar Uddin Ahmad   +3 more
openaire   +1 more source

Pomegranate ellagitannins inhibit α-glucosidase activity in vitro and reduce starch digestibility under simulated gastro-intestinal conditions [PDF]

, 2014
Pomegranate extract was tested for its ability to inhibit α-amylase and α-glucosidase activity. Pomegranate extract strongly inhibited rat intestinal α-glucosidase in vitro whereas it was a weak inhibitor of porcine α-amylase. The inhibitory activity was
BELLESIA, ANDREA, TAGLIAZUCCHI, Davide, VERZELLONI, Elena   +2 more
core   +1 more source

Chemical composition, antioxidant and alpha-Glucosidase-Inhibiting activities of the aqueous and hydroethanolic extracts of Vaccinium myrtillus Leaves [PDF]

, 2017
Vaccinium myrtillus (bilberry) leaf is traditionally used in southeastern Europe for the treatment of diabetes. In the present study, the ability of bilberry leaf extracts to inhibit carbohydrate-hydrolyzing enzymes and restore glutathione concentration ...
Bljajic, Kristina, Cacic, Ana, de Carvalho, Isabel Saraiva, Jablan, Jasna, Koncic, Marijana Zovko, Petlevski, Roberta, Sostaric, Nina, Vujic, Lovorka   +7 more
core   +1 more source

In Vitro Inhibition of α-Amylase and α-Glucosidase by Different Parts of Amla Plant (Phyllanthus emblica L) [PDF]

Pharmacology and Clinical Pharmacy Research, 2018
Amla plant (Phyllanthus emblica L) has been empirically used to treat diabetes. The aim of this study was to determine the most potential part of amla plant that can be used as α-glucosidase and α-amylase inhibitors.
Novi I. Fauzi, Maria Ulfah, Syarif Hamdani, Saeful Hidayat   +3 more
doaj   +1 more source

Design, synthesis, in vitro, and in silico biological evaluations of coumarin-indole hybrids as new anti-α-glucosidase agents

BMC Chemistry, 2022
Background A series of coumarin-indole hybrids was synthesized as the new α-glucosidase inhibitors. The title hybrids were considered as α-glucosidase inhibitors because had two active pharmacophores against α-glucosidase: coumarin and indole.
Davood Rezapour Niri, Mohammad Hosein Sayahi, Somayeh Behrouz, Ali Moazzam, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Bagher Larijani, Hossein Rastegar, Maryam Mohammadi-Khanaposhtani, Mohammad Mahdavi   +9 more
doaj   +1 more source

Phytochemical profile, antioxidant activity, and inhibition of α-amylase and α-glucosidase for banana central pseudo-stem juice [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2021
The use of natural products to inhibit α-amylase and α-glucosidase is a strategy in the treatment of diabetes. This study investigated the phytochemical profile and antioxidant activity of, and α-amylase and α-glucosidase inhibition by banana central ...
Intira Koodkaew, Khwanruedee Chaiyawan, Pimchanok Satapoomin   +2 more
doaj   +1 more source