Results 81 to 90 of about 997,954 (175)

Evaluation of antioxidant and antiproliferative activities of shogaol and its modulatory effects on key metabolic enzymes

Discover Food
Phenolic compounds are versatile bioactive molecules, particularly in food applications. In this study, the antioxidant capacity of Shogaol, a member of the phenolic class, was evaluated using several methods.
İsmail Yapıcı, İlhami Gülçin
doaj   +1 more source

UPLC-ESI/MSn metabolic profiling of Cedrela odorata L. and Toona ciliata M. Roem and in vitro investigation of their anti-diabetic activity supported with molecular docking studies

Frontiers in Chemistry
IntroductionThe genus Cedrela is one of the phytochemically rich genera of the family Meliaceae. In this study, two Cedrela species, namely, Cedrela odorata and Toona ciliata M.
Heba A. S. El-Nashar, Ayman M. Al-Qaaneh, Ayman M. Al-Qaaneh, Md. Shimul Bhuia, Md. Shimul Bhuia, Raihan Chowdhury, Raihan Chowdhury, Mostafa A. Abdel-Maksoud, Hossam Ebaid, Abdul Malik, Muhammad Torequl Islam, Muhammad Torequl Islam, Muhammad Torequl Islam, Mohammed Aufy, Esraa A. Elhawary   +14 more
doaj   +1 more source

Fermentation of Danggui Buxue Tang, an ancient Chinese herbal mixture, together with Lactobacillus plantarum enhances the anti-diabetic functions of herbal product

Chinese Medicine, 2020
Background Danggui Buxue Tang (DBT), an ancient Chinese herbal decoction containing Astragali Radix and Angelicae Sinensis Radix at a ratio of 5: 1, is prescribed for menopausal women.
Rui Guo, Shuchen Guo, Xiong Gao, Huaiyou Wang, Weihui Hu, Ran Duan, Tina T. X. Dong, Karl W. K. Tsim   +7 more
doaj   +1 more source

From Dysbiosis to Disease: How Vaginal Microbiota Shape Group B Streptococcus Pathogenesis

ChemBioChem, Volume 27, Issue 20, 28 October 2026.
Lactobacillus crispatus plays a critical role in the vaginal microbiome. Limiting glucose shifts metabolism toward HMO consumption and amino acid metabolism. These actions enable alkali production and competition. Homeostasis, characterized by dense Lactobacilli colonization and suppression of pathogens, provides resistance to dysbiosis.
Julie A. Talbert, Steven D. Townsend
wiley   +1 more source

Synthesis of Thiohydantoin-Castanospermine Glycomimetics as Glycosidase Inhibitors

, 2016
The preparation of bicyclic carbohydrate mimics related to (+)-castanospermine incorporating a thiohydantoin moiety is reported. The synthetic approach is compatible with molecular diversity-oriented strategies and involves α-azidoesters, built at the C ...
Matilde Aguilar-Moncayo (2358781), José M. García Fernández (1710094), M. Isabel García-Moreno (1991632), Carmen Ortiz Mellet (1710091)   +3 more
core   +1 more source

Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes

Anais da Academia Brasileira de Ciências
Leaves of Psidium guajava L. (guava) have been widely used in the popular way for prevention and treatment of various diseases. Thus, the objective of this study was to evaluate the inhibitory potential of leaves aqueous extract from three cultivars of P.
ANDERSON A. SIMÃO, TAMARA R. MARQUES, SILVANA MARCUSSI, ANGELITA D. CORRÊA   +3 more
doaj   +1 more source

N-glycosidase activity of [alpha]- and [beta]-momorcharins.

, 1994
Poon Yin-tat.Thesis (M.Phil.)--Chinese University of Hong Kong, 1994.Includes bibliographical references (leaves 101-111).ACKNOWLEDGEMENTS --- p.IABSTRACT --- p.IILIST OF ABBREVIATIONS --- p.IVTABLE OF CONTENTS --- p.VChapter CHAPTER 1 ...

core  

Effect of ultrasonic degradation on the physicochemical property, structure characterization, and bioactivity of Houttuynia cordata polysaccharide

Ultrasonics Sonochemistry
This study aimed to evaluate the influence of ultrasonic degradation on Houttuynia cordata polysaccharide (HCP) physicochemical properties, structure characterization, and bioactivities.
Mohammed Mansour, Ramy M. Khoder, Lin Xiang, Lan Lan Zhang, Ahmed Taha, Alsadig Yahya, Ting Wu, Hassan Barakat, Ibrahim Khalifa, Xu Xiaoyun   +9 more
doaj   +1 more source

In-vitro α amylase and glycosidase inhibitory effect of ethanolic extract of antiasthmatic drug - Shirishadi

Journal of Advanced Pharmaceutical Technology & Research, 2013
Asthma and diabetes have strong relationship; both are cause and effect of each other. Oxidative stress due to bronchial asthma may cause insulin resistance whereas lack of proper insulin can cause defective smooth muscle relaxant.
Divya Kajaria, Ranjana, Jyotishankar Tripathi, Yamini Bhushan Tripathi, Srikant Tiwari   +4 more
doaj   +1 more source

Investigation of the Effect of Gingerol on α-Glycosidase Cholinesterases and Monoamine Oxidase Enzymes: Antioxidant Activity and In Silico Study

This study examined the effects of gingerol, an active ingredient in ginger, on monoamine oxidases (MAO)-A and B, acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and α-glycosidase enzymes as in vitro. The IC50 values were calculated for MAO-A,
Saglamtas, Ruya, GÜLÇİN, İlhami
core   +1 more source