Results 11 to 20 of about 7,246 (143)

Association of central α-klotho with dopaminergic and melanocortin receptors on feed intake regulation in chicken [PDF]

Poultry Science
This study aimed to detemine association of central α-klotho with dopaminergic and melanocortin receptors on feed intake regulation in chicken. 264 meat-type chicken were included 6 experiments, each containing 4 groups.
Yaser Hassania, Shahin Hassanpour, Morteza Zendehdel, Bita Vazir   +3 more
doaj   +2 more sources

The inflection point: α-Klotho levels and the risk of all-cause mortality [PDF]

Frontiers in Endocrinology
PurposeThe controversial nature of the association between α-Klotho and mortality risk in the general population warrants further investigation. This study aims to examine the correlation between circulating α-Klotho levels and the risk of all-cause ...
Jianling Song, Hong Li, Xiangdong Fang
doaj   +2 more sources

Sex differences between atherogenic index of plasma and α-klotho levels in middle-aged and older adults: NHANES 2007–2016 [PDF]

Frontiers in Endocrinology
ObjectiveKlotho is an anti-aging gene, and the α-klotho protein it encodes reportedly has cardiovascular protective effects. The atherogenic index of plasma (AIP) is a novel and comprehensive lipid index that correlates with atherosclerotic burden and is
Cheng Zuo, Zi-Duo Shen, Yaojun Lu
doaj   +2 more sources

Sex differences in the association between serum α-Klotho levels and hyperlipidemia: a cross-sectional study from NHANES 2013–2016 [PDF]

Scientific Reports
This study assessed the association between serum α-Klotho levels and hyperlipidemia. The aim was to ascertain the potential of serum α-Klotho levels as a predictive biomarker for hyperlipidemia.
Yu Han, Chao Liu, Ying Nie, Xijuan Jiang, Na An, Yabin Qin, Yinghua Ma, Zhihua An, Yile Zhao   +8 more
doaj   +2 more sources

Independent and Combined Associations of Urinary Heavy Metal Exposures with Serum α-Klotho in Middle-Aged and Older Adults [PDF]

Toxics
α-Klotho is an anti-aging protein linked to various age-related diseases. Environmental metal exposure has been associated with oxidative stress and aging, but its effect on α-Klotho levels remains unclear.
Xinliang Zheng, Wenxin Zhou, Zhuoying Jiang, Chan Ding, Minqian Feng, Yongxin Li, Fitri Kurniasari, Shuanghua Xie, Huadong Xu   +8 more
doaj   +2 more sources

Association between α-klotho levels and adults with COPD in the United States [PDF]

Frontiers in Medicine
PurposeChronic obstructive pulmonary disease (COPD) is accompanied by increased inflammation, persistent lung function decline, and extensive lung injury. Klotho, a well-known antiaging protein, has anti-inflammatory and antioxidative effects.
Dan Yan
doaj   +2 more sources

α-klotho reduces susceptibility to osteoarthritis: evidence from cross-sectional studies and Mendelian randomization [PDF]

Frontiers in Endocrinology
BackgroundDespite extensive research, the association between serum α-klotho levels and osteoarthritis (OA) remains unclear, predominantly relying on findings from OA mouse models.
Zhao Li, Zhong Li, Qisheng Cheng, Xinlin Nie, Yu Cui, Bing Du, Taotao Ren, Yibo Xu, Teng Ma   +8 more
doaj   +2 more sources

Causal association between circulating α-Klotho levels and venous thromboembolism: a two-sample Mendelian randomization study [PDF]

Thrombosis Journal
Background α-Klotho may involve in the occurrence and development of venous thromboembolism (VTE). However, the underlying relationship between circulating α-Klotho levels and VTE is still unclear.
Yanmin Song, Liping Cao, Hui Long
doaj   +2 more sources

Additional file 1: of Evaluation of the effect of oral taurine supplementation on fasting levels of fibroblast growth factors, β-Klotho co-receptor, some biochemical indices and body composition in obese women on a weight-loss diet: a study protocol for a double-blind, randomized controlled trial

, 2019
Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2013 Checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 122 kb)
Haidari, Fatemeh, Asadi, Maryam, mohammadi-asl, Javad, Ahmadi-Angali, Kambiz   +3 more
openaire   +1 more source

Sugar sweetened beverage consumption is positively associated with Klotho levels at two years of age in LatinX youth

BMC Nutrition, 2021
Background Klotho is an anti-aging protein mainly expressed in the kidneys with a smaller amount expressed in adipose tissue. Klotho effects include roles in reducing oxidative stress, insulin signaling, adipogenesis and glucose metabolism.
Sofia Villagomez, Dena B. Dubal, Jessica Hawkins, Dan Wang, Janet M. Wojcicki   +4 more
doaj   +1 more source