Results 111 to 120 of about 3,332,267 (201)

Investigating the chemistry of lipoyl synthase

, 2008
The radical SAM protein lipoyl synthase (LipA) is essential for lipoic acid biosynthesis via sulfur insertions into the unactivated C6 and C8 centres of a protein-bound octanoyl group.
Douglas, Paul
core   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, Volume 4, Issue 3, September 2026.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Effects of Quercetin and α-Lipoic Acid on α-Cypermethrin-Induced Oxidative Stress in Rats

, 2015
This study evaluated the effects of quercetin and α-lipoic acid on the antioxidant status of α-Cypermethrin (α-CYP) treated rats. 30 rats were randomly divided five experimental groups thus: (i) control group, (ii) α-CYP alone (14.5 mg kg-1 body weight ...
Rotimi, Solomon, Rotimi, Oluwakemi A, Ugwu, Emmanuel, Adelani, Isaacson, Essien, Imaobong   +4 more
core  

Comprehensive Peptide Profiling Reveals the Influence of Streptococcus Thermophilus, Lactobacillus Delbrueckii Subsp. bulgaricus, and Endogenous Milk Proteases on the Hydrolysis of Milk Proteins During Early‐Stage Lactic Acid Fermentation

ChemFoodChem, Volume 2, Issue 3, September 2026.
Untargeted peptide profiling investigates how S. thermophilus, Lb. bulgaricus, and endogenous milk enzymes impact proteolysis during early‐stage milk fermentation. ≥ 3000 identified peptides show the strongest influence of LB on the peptide profile and number of bioactive peptides. Shorter peptides are mostly formed by LB and hydrolyzed by ST.
Eva Beck, Lena Riedinger, Sevim Dalabasmaz, Joachim Stützer, Luisa Bähr, Rohtraud Pichner, Monika Pischetsrieder   +6 more
wiley   +1 more source

Mechanical stability in flexible perovskite solar cells: Interface engineering and device design

FlexMat, Volume 3, Issue 3, Page 502-539, September 2026.
Statistics of the improvement methods for f‐PSCs. Abstract Flexible perovskite solar cells (f‐PSCs) demonstrate significant potential for application in next‐generation wearable electronic devices and photovoltaic building integration due to their high power conversion efficiency and excellent power‐to‐weight ratio. However, the inherent brittleness of
Hong‐Yi Hou, Xin‐Yi Zeng, Jian‐Xin Tang, Yan‐Qing Li   +3 more
wiley   +1 more source

Effects of Different Dietary Levels of Chia (Salvia hispanica L.) and Quinoa (Chenopodium quinoa Willd.) on Adipokines and Anthropometric Parameters in Rats

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Six weeks dietary supplementation with chia (Salvia hispanica L.) and quinoa (Chenopodium quinoa Willd.) modulated adipokine profiles and anthropometric parameters in male Wistar rats: 20% chia and quinoa decreased serum chemerin, resistin, and insulin levels while increasing omentin; 10%–20% supplementation decreased visfatin; all supplemented diets ...
Kübra İspir, Sevinç Yücecan, Ilyas Bozkurt, Halit Imik   +3 more
wiley   +1 more source

Temperature-dependent interaction between niacin/D-panthenol in aqueous α-lipoic acid: Physicochemical and spectroscopic analysis

Chemical Thermodynamics and Thermal Analysis
Volumetric and acoustic characteristics of binary (niacin/d-panthenol + water) and ternary (niacin/d-panthenol + α-lipoic acid + water) systems were analysed to understand solute–solvent and solute–solute interactions.
Rupavalli Talabattula, Nabaparna Chakraborty, Kailash Chandra Juglan   +2 more
doaj   +1 more source

Intelligent design of artificial biocatalyst for biomedical diseases

Journal of Intelligent Medicine, Volume 3, Issue 3, Page 220-249, September 2026.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang, Nan Song, Huanhuan Qiao, Si Sun   +3 more
wiley   +1 more source

A Deep Clinical and Biochemical Characterization of a Patient With Combined Malonic and Methylmalonic Aciduria (CMAMMA)

JIMD Reports
Combined malonic and methylmalonic aciduria (CMAMMA) is an inborn error of metabolism caused by a deficiency in mitochondrial malonyl‐CoA synthetase, the enzyme responsible for activating malonic acid (MA) to malonyl‐CoA, a precursor of lipoic acid.
Vincenza Gragnaniello, Alfonso Galderisi, Sara Tucci, Mara Doimo, Marianna Caterino, Christian Loro, Chiara Cazzorla, Margherita Ruoppolo, Leonardo Salviati, Alberto B. Burlina   +9 more
doaj   +1 more source

Irritable Bowel Disease: Think Malonic and Methylmalonic Aciduria (CMAMMA)!

JIMD Reports, Volume 67, Issue 5, September 2026.
ABSTRACT Combined malonic and methylmalonic aciduria (CMAMMA; OMIM 614265) is a rare disorder of mitochondrial fatty acid synthesis caused by pathogenic variants in the ACSF3 gene, which encodes malonyl‐CoA synthetase. The clinical presentation is highly heterogeneous and may include seizures, memory impairment, psychiatric manifestations, and ...
Khaled Alatibi, Martin J. Hug, Sara Tucci   +2 more
wiley   +1 more source