Results 101 to 110 of about 29,401 (218)

Hedgehog Pathway Activation Alters Ciliary Signaling in Primary Hypothalamic Cultures [PDF]

, 2019
Primary cilia dysfunction has been associated with hyperphagia and obesity in both ciliopathy patients and mouse models of cilia perturbation. Neurons throughout the brain possess these solitary cellular appendages, including in the feeding centers of ...
Antonellis, Patrick J., Bansal, Ruchi, Baucum, Anthony J., Berbari, Nicolas F., Cummins, Theodore R., Engle, Staci E., Reiter, Jeremy F., Whitehouse, Logan S.   +7 more
core   +1 more source

ACTH suppression and adverse effects of cabergoline in horses with pituitary pars intermedia dysfunction

Equine Veterinary Education, EarlyView.
Summary Background The diagnosis and management of pituitary pars intermedia dysfunction (PPID) in horses includes evaluating abnormal plasma concentrations of adrenocorticotrophic hormone (ACTH). Treatment commonly includes the oral dopamine agonist pergolide mesylate, which suppresses the pathologic overproduction of ACTH.
A. Bracken, H. Tyra, M. Vetter, K. Kiger, S. Rao, L. Bass   +5 more
wiley   +1 more source

α-Melanocyte-Stimulating Hormone Protects Retinal Vascular Endothelial Cells from Oxidative Stress and Apoptosis in a Rat Model of Diabetes

PLoS ONE, 2014
Aims Oxidative stress and apoptosis are among the earliest lesions of diabetic retinopathy. This study sought to examine the anti-oxidative and anti-apoptotic effects of α-melanocyte-stimulating hormone (α-MSH) in early diabetic retinas and to explore ...
Lijuan Zhang, Lijie Dong, Xun Liu, Yuanfeng Jiang, Lingjun Zhang, Xiaomin Zhang, Xiaorong Li, Yan Zhang   +7 more
semanticscholar   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

Use of a Tissue Engineered Human Skin Model to Investigate the Effects of Wounding and of an Anti-Inflammatory on Melanoma Cell Invasion [PDF]

, 2016
An increasing number of studies suggest inflammation stimulates tumour invasion. In melanoma, despite recent advances in targeted therapy and immunomodulatory therapies, this cancer remains difficult to treat.
MacNeil, S., Marques, C.M.D.G.
core   +1 more source

Recent advances of emergent extraction technologies to enhance bioactive compounds extraction of microalgae—An overview towards application in cosmetics

International Journal of Cosmetic Science, EarlyView.
Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh, Lucília da P. da Silva, Carlos A. Pinto, Rosário Martins, Alexandra P. Marques, Jorge A. Saraiva   +5 more
wiley   +1 more source

Ishophloroglucin A Isolated from Ishige okamurae Suppresses Melanogenesis Induced by α-MSH: In Vitro and In Vivo

Marine Drugs, 2020
Diphlorethohydroxycarmalol (DPHC) isolated from Ishige okamurae (IO) showed potential whitening effects against UV-B radiation. However, the components of IO as well as their molecular mechanism against α-melanocyte-stimulating hormone (α-MSH) have not ...
Xining Li, Hye-Won Yang, Yunfei Jiang, Jae-Young Oh, You-Jin Jeon, Bomi Ryu   +5 more
doaj   +1 more source

Dynamic colour change predicts movement behaviour in a diadromous fish

Journal of Fish Biology, EarlyView.
Abstract Dynamic changes in colour and pattern facilitate key behavioural functions in animals, particularly camouflage for predator avoidance. However, the benefits of colour change depend on the environmental and behavioural contexts. We tested how colour change interacts with movement behaviour in a freshwater fish by filming individuals in an open ...
Joshua S. Barrow, John R. Morrongiello
wiley   +1 more source

Melanocortin Regulation of Inflammation

Frontiers in Endocrinology, 2019
Adrenocorticotropic hormone (ACTH), and α-, β-, and γ-melanocyte-stimulating hormones (α-, β-, γ-MSH), collectively known as melanocortins, together with their receptors (melanocortin receptors), are components of an ancient modulatory system.
Wei Wang, Dong-Yu Guo, Yue-Jun Lin, Ya-Xiong Tao   +3 more
doaj   +1 more source

The main actors involved in parasitization of Heliothis virescens larva [PDF]

, 2012
At the moment of parasitization by another insect, the host Heliothis larva is able to defend itself by the activation of humoral and cellular defenses characterized by unusual reactions of hemocytes in response to external stimuli.
A Arora, A Franchini, A Grimaldi, A Kubiak-Wlekły, A Ruggeri, A Slominski, AG Pearse, AJ Cohen, AMF Falleiros, Annalisa Grimaldi, AP Gupta, AR Johnson, AS Mostaert, AS Mostaert, B Scharrer, B Scharrer, BT Baune, C Glabe, C Ribeiro, D Hafez, D Malagoli, Davide Malagoli, DG Remick, DM Fowler, DP Knight, DS Wang, E Caselgrandi, E Ottaviani, E Ottaviani, E Ottaviani, E Ottaviani, EM Smith, Enzo Ottaviani, F Pennacchio, F Pennacchio, G Bidla, G Lorkowski, G Moellmann, Gianluca Tettamanti, H Du, H Le Vine III, H Nakagawa, J Beaulaton, J Drake, J Greenwald, JB Whitfield, JC Castillo, JF Hillyer, JF Hillyer, K Wolff, KL Camplejohn, L Zheng, M Brehélin, M Salzet, M Salzet, MA Cotter, Magda de Eguileor, MD Lavine, MM Bradford, N Iwata, NA Ratcliffe, O Duvaux-Miret, O Schmidt, P Bossù, P Falabella, P Verhaert, Patrizia Falabella, PG Giulianini, PO Lawrence, Q Chen, R Ferrarese, RH Swerdlow, Roberto Valvassori, Rossana Girardello, S Alboni, S Alboni, S Diment, S El-Amouri, S Genedani, T Barka, T Loof, TC Squier, Terenzio Congiu, UK Laemmli, VM Felton, W Korytowsky, WJ Meilandt, X Zhu, Y Christen   +88 more
core   +1 more source