Results 81 to 90 of about 9,462 (144)

Effectiveness and Safety of Setmelanotide in a Patient With a Heterozygous PCSK1 Deficiency

Obesity, Volume 34, Issue S2, Page 70-74, September 2026.
ABSTRACT Setmelanotide, a melanocortin 4 receptor (MC4R) agonist, is a promising pharmacological treatment option for people with rare monogenic obesity conditions affecting the leptin‐melanocortin signaling pathway, including proprotein convertase subtilisin/kexin type 1 (PCSK1) gene mutations.
Ellina Lytvyak, Arshdeep Rattol, Eduardo Grunvald   +2 more
wiley   +1 more source

Baicalein Inhibits α-Melanocyte-stimulating Hormone-stimulated Melanogenesis via p38 Mitogen-activated Protein Kinase Pathway in B16F10 Mouse Melanoma Cells. [PDF]

J Cancer Prev, 2023
Oh MC, Fernando PDSM, Piao MJ, Kang KA, Herath HMUL, Hyun JW.   +5 more
europepmc   +1 more source

Shelterin TPP1 Promotes Hair Regeneration Through Activating Bulge Hair Follicle Stem Cells

Aging Cell, Volume 25, Issue 9, September 2026.
Elongation of telomeres by increasing TPP1, through genetic and pharmacological approaches, promotes hair follicle bulge stem cell mobilization and migration, leading to accelerated telogen‐to‐anagen transition and hair regeneration. This work identifies TPP1 as a master regulator and therapeutic target for alopecia. ABSTRACT Telomere shortening drives
Lihui Wang, Bihan Zhao, Jiahui Yang, Ying Liang, Yitian Yao, Xiao Xiao, Long Yang, Jinghao Xia, Haoze Li, Ling Gao, Jun Zhang, Tianci Su, Hao Xu, Jiacheng Zhang, Hongyan Wang, Jun Liu, Xiaojing Hong, Jun‐Ping Liu   +17 more
wiley   +1 more source

ACTH suppression and adverse effects of cabergoline in horses with pituitary pars intermedia dysfunction

Equine Veterinary Education, Volume 38, Issue 9, Page e622-e630, September 2026.
Summary Background The diagnosis and management of pituitary pars intermedia dysfunction (PPID) in horses includes evaluating abnormal plasma concentrations of adrenocorticotrophic hormone (ACTH). Treatment commonly includes the oral dopamine agonist pergolide mesylate, which suppresses the pathologic overproduction of ACTH.
A. Bracken, H. Tyra, M. Vetter, K. Kiger, S. Rao, L. Bass   +5 more
wiley   +1 more source

Correction: Mitigating the toxicity of palmitoylated analogue of α-melanocyte stimulating hormone(11-13) by conjugation with gold nanoparticle: characterisation and antibacterial efficacy against methicillin sensitive and resistant Staphylococccus aureus. [PDF]

World J Microbiol Biotechnol, 2022
Mitra S, Mondal AH, Mukhopadhyay K.
europepmc   +1 more source

Anti‐Aging Potential of Callus Culture: Mechanisms, Efficacy and Future Trends

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Callus culture technology revolutionizes skin antiaging research, offering a sustainable and efficient method for producing bioactive compounds with potent geroprotective properties. This plant tissue and cell culture technique enables the controlled biosynthesis of beneficial phytochemicals while mitigating the variability and ...
Amir Mohammad Sharafi, Ali Khajeei, Maryam Hasan Zadeh Navroodi, Soheila Mokari, Seydeh Halimeh Najafi, Mohaddeseh Argha, Faezeh Talaei Shahmirzadi, Parina Asgharian, Tooba Gholikhani   +8 more
wiley   +1 more source

Efficacy and Safety of Yellow Light Monotherapy Versus Yellow Light Combined With 20% Vitamin C for the Treatment of Melasma: A Single‐Center, Randomized, Double‐Blind, Placebo‐Controlled Clinical Study

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Melasma treatment remains challenging due to limited effective and safe options. This study evaluated the efficacy and safety of yellow light phototherapy alone versus combined with 20% vitamin C in treating melasma. Methods Seventy‐one patients were randomly assigned to receive twice‐weekly yellow light phototherapy combined with ...
Dan Du, Xu Liu, Yuwei Huang, Shuwei Wu, Xian Jiang   +4 more
wiley   +1 more source

Mitigating the toxicity of palmitoylated analogue of α-melanocyte stimulating hormone(11-13) by conjugation with gold nanoparticle: characterisation and antibacterial efficacy against methicillin sensitive and resistant Staphylococccus aureus. [PDF]

World J Microbiol Biotechnol, 2022
Mitra S, Mondal AH, Mukhopadhyay K.
europepmc   +1 more source

Natural Agents for Preventing Skin Damage Induced by Visible Light: A Systematic Review of Preclinical and Clinical Evidence

Photodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 5, September 2026.
ABSTRACT Background/Purpose Visible light (VL), and particularly high‐energy visible light (HEVL), reaching Earth's surface has emerged as a relevant contributor to skin damage. VL has been implicated in oxidative stress, inflammation, pigmentation disorders, and photoaging, especially in individuals with darker skin phototypes.
Azahara Rodríguez‐Luna, Alicia Zamarrón, Cristina García‐Muñoz, Juan‐Carlos Hernández‐Rodríguez, Henry W. Lim, Salvador González   +5 more
wiley   +1 more source

Gamma-Aminobutyric Acid (GABA) Inhibits α-Melanocyte-Stimulating Hormone-Induced Melanogenesis through GABA_A and GABA_B Receptors. [PDF]

Int J Mol Sci, 2021
Molagoda IMN, Kavinda MHD, Ryu HW, Choi YH, Jeong JW, Kang S, Kim GY.   +6 more
europepmc   +1 more source