Results 31 to 40 of about 9,462 (144)

Targeted proteomics reveal α-MSH-like Enterobacterial ClpB protein in gut microbiota of patients with anorexia nervosa

npj Biofilms and Microbiomes
α-melanocyte-stimulating hormone (α-MSH) is an anorexigenic peptide. In this exploratory study, a targeted proteomic approach was used to detect α-MSH-like bacterial proteins in the gut microbiota of patients with anorexia nervosa (AN) and healthy ...
Lisa Bremard, Lisa Wallart, Emilie Lahaye, Mohamed Amine Ben Mlouka, Jochen Seitz, Beate Herpertz-Dahlmann, Sergueï O. Fetissov   +6 more
doaj   +1 more source

Anti–melanogenic properties of FBCC–EP850 derived from Carex pumila Thunb

Asian Pacific Journal of Tropical Biomedicine
Objective: To elucidate the anti-melanogenic potential of Carex pumila Thunb. extract (FBCC-EP850). Methods: A collection of 180 plant extracts was tested for inhibition of mushroom tyrosinase activity using an in vitro assay.
Mirissa Hewage Dumindu Kavinda, Jinkuk Park, Nayeong Kim, Yung Hyun Choi, Gi-Young Kim   +4 more
doaj   +1 more source

Alpha-melanocyte stimulating hormone (α-MSH) is a post-caspase suppressor of apoptosis in RAW 264.7 macrophages. [PDF]

PLoS ONE, 2013
The neuropeptide alpha-melanocyte stimulating hormone (α-MSH) is an important regulator of immune cell activity within the immunosuppressive ocular microenvironment.
Andrew W Taylor
doaj   +1 more source

Depletion of Alpha-Melanocyte-Stimulating Hormone Induces Insatiable Appetite and Gains in Energy Reserves and Body Weight in Zebrafish

Biomedicines, 2021
The functions of anorexigenic neurons secreting proopiomelanocortin (POMC)/alpha-melanocyte-stimulating hormone (α-MSH) of the melanocortin system in the hypothalamus in vertebrates are energy homeostasis, food intake, and body weight regulation. However,
Yang-Wen Hsieh, Yi-Wen Tsai, Hsin-Hung Lai, Chi-Yu Lai, Chiu-Ya Lin, Guor Mour Her   +5 more
doaj   +1 more source

Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy, Jesse Richards, Brooke R. Sweeney, Seema Kumar, Katie E. Queen, Joshua Zaritsky, Carl H. Cramer, Elias I. Traboulsi, Brittni A. Scruggs, Erica E. Davis, Ekaterina Keifer, Emma McGibbon, Timothy Ogden, Bendert De Graaf, Tonia Hymers, Elizabeth Forsythe, Philip Beales   +16 more
wiley   +1 more source

α-Melanocyte-stimulating hormone directly increases the plasma calcitonin level and involves calcium metabolism in goldfish

International Aquatic Research, 2018
The effects of α-melanocyte-stimulating hormone (α-MSH) on calcium metabolism were examined with goldfish. The scales on the left side of goldfish bodies were removed to allow the regeneration of scales under anesthesia.
Takahiro Ikari, Yuki Kobayashi, Yoichiro Kitani, Toshio Sekiguchi, Masato Endo, Akira Kambegawa, Kiyoshi Asahina, Atsuhiko Hattori, Yoshiaki Tabuchi, Thumronk Amornsakun, Kanta Mizusawa, Akiyoshi Takahashi, Nobuo Suzuki   +12 more
doaj   +1 more source

Inhibitory effect of Cyrtomium falcatum on melanogenesis in α-stimulated B16F10 murine melanoma cells

Asian Pacific Journal of Tropical Biomedicine, 2023
Objective: To explore the anti-melanogenic potential of Cyrtomium falcatum. Methods: The effects of Cyrtomium falcatum crude extract and its solvent fractions on tyrosinase activity, melanin content, and the expressions of melanogenesis-related genes and
Xian-Rong Zhou, Jung Hwan Oh, Fatih Karadeniz, Hyunjung Lee, Hyo Eun Kim, Migeon Jo, Youngwan Seo, Chang-Suk Kong   +7 more
doaj   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

The Melanocortin System in Control of Inflammation

The Scientific World Journal, 2010
Melanocortin peptides, the collective term for α-, β-, and γ-melanocyte-stimulating hormone (α-, β-, γ-MSH) and adrenocorticotropic hormone (ACTH), are elements of an ancient modulatory system.
Anna Catania, Caterina Lonati, Andrea Sordi, Andrea Carlin, Patrizia Leonardi, Stefano Gatti   +5 more
doaj   +1 more source

Reduced α-MSH Underlies Hypothalamic ER-Stress-Induced Hepatic Gluconeogenesis

Cell Reports, 2015
Alterations in ER homeostasis have been implicated in the pathophysiology of obesity and type-2 diabetes (T2D). Acute ER stress induction in the hypothalamus produces glucose metabolism perturbations.
Marc Schneeberger, Alicia G. Gómez-Valadés, Jordi Altirriba, David Sebastián, Sara Ramírez, Ainhoa Garcia, Yaiza Esteban, Anne Drougard, Albert Ferrés-Coy, Analía Bortolozzi, Pablo M. Garcia-Roves, John G. Jones, Bruno Manadas, Antonio Zorzano, Ramon Gomis, Marc Claret   +15 more
doaj   +1 more source