Results 11 to 20 of about 34,320 (185)

Prevalence and molecular characterization of common thalassemia among people of reproductive age in the border area of Guangxi-Yunnan-Guizhou province in Southwestern China

open access: yesHematology, 2022
Objectives: Thalassemia, the most common global monogenetic disorder, is highly prevalent in southern China. Epidemiological and molecular characterization of thalassemia is important for designing appropriate prevention strategies in high-risk areas ...
GuiDan Xu   +10 more
doaj   +1 more source

Vitamin D, Calcium and Phosphor in Patients with β-Thalassemia Major [PDF]

open access: yesINDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2019
There has been many reports that patients with β-thalassemia major have bone problems such as thinning of the bone, bone fragility and pathological fractures. For so many years it was believed that the bone problems is mainly caused by marrow expansion due to compenstation of the bone marrow to handle the chronic anaemia and hiypoxia in β-thalassemia
Ade Hariza Harahap   +2 more
openaire   +1 more source

Epidemiology of thalassemia among the hill tribe population in Thailand.

open access: yesPLoS ONE, 2021
BackgroundThalassemia is a severe disease that occurs due to abnormalities in hemoglobin genes. Various genetic factors in different populations lead to different clinical manifestations of thalassemia disease, particularly among people who have a long ...
Tawatchai Apidechkul   +4 more
doaj   +1 more source

Prevalence of iron-deficiency anemia in pregnant women with various thalassemia genotypes: Thoughts on iron supplementation in pregnant women with thalassemia genes

open access: yesFrontiers in Nutrition, 2022
BackgroundThere are limited studies on iron-deficiency anemia (IDA) in carriers of various thalassemia genotypes. However, for pregnant women (PW) with high iron demand, ignoring the phenomenon of carrying the thalassemia genes combined with IDA may lead
Min Wang   +6 more
doaj   +1 more source

Molecular Epidemiology and Hematologic Characterization of Thalassemia in Guangdong Province, Southern China

open access: yesClinical and Applied Thrombosis/Hemostasis, 2022
Introduction: About 2% of the population in the world are carriers of the thalassemia gene. Thalassemia is highly prevalent in Southern China, and traditional clinical testing methods would cause missed diagnosis of partial static thalassemia.
Jiajia Xian MD   +6 more
doaj   +1 more source

The prevalence and genetic disorders spectrum of thalassemia among breast cancer patients in Jiangxi province, China

open access: yesFrontiers in Genetics, 2022
Background: Thalassemia is a common inherited hematological disease with genetic disorders characterized by imbalanced synthesis of the globin chains.
Jingxian Ding   +5 more
doaj   +1 more source

Nutritional status of young children with inherited blood disorders in western Kenya. [PDF]

open access: yes, 2014
To determine the association between a range of inherited blood disorders and indicators of poor nutrition, we analyzed data from a population-based, cross-sectional survey of 882 children 6–35 months of age in western Kenya.
Ruth, LJ   +4 more
core   +1 more source

Case report: Identification of a novel triplication of alpha-globin gene by the third-generation sequencing: pedigree analysis and genetic diagnosis

open access: yesHematology, 2023
Background Thalassemia, a common autosomal hereditary blood disorder worldwide, mainly contains α- and β-thalassemia. The α-globin gene triplicates allele is harmless for carriers, but aggravates the phenotype of β-thalassemia.
Yujiao Chen   +5 more
doaj   +1 more source

Protein C and Protein S Levels in β-Thalassemia Major Patients in Erbil, Kurdistan Region

open access: yesCellular and Molecular Biology, 2020
Oxygen is transported in the blood through red blood cells and a protein called hemoglobin. The protein consists of two alpha and two beta chains. The lack of any of these chains is caused by the malfunction of the genes that produce them, and can lead to a genetic disease called thalassemia.
Tareefa Kakakhan, Hadi   +2 more
openaire   +3 more sources

Prevalence of Inherited Hemoglobin Disorders and Relationships with Anemia and Micronutrient Status among Children in Yaoundé and Douala, Cameroon. [PDF]

open access: yes, 2017
Information on the etiology of anemia is necessary to design effective anemia control programs. Our objective was to measure the prevalence of inherited hemoglobin disorders (IHD) in a representative sample of children in urban Cameroon, and examine the ...
Brown, Kenneth H   +8 more
core   +1 more source

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