Results 91 to 100 of about 3,518 (150)

electroacupuncture upregulates α7nAChR and suppresses JAK2STAT3 signaling pathway in dorsal root ganglion(DRG)20180820.xlsx

, 2018
Methods: The SNI-induced neuropathic pain rat model was used in this study. After application of 2Hz EA treatment to SNI rats on day 3, 7, 14, and 21 post-surgery, the α7nAChR, JAK2/STAT3, pro-inflammatory cytokines IL-1β, IL-6 and anti-inflammatory ...
Meng Xue (164750), Cheng Huang (5781752), Qian Jiang (216582), Ying Wang (11406), Zhi-Hua Huang (1547317), Yang-Yang Xia (4271059)   +5 more
core   +1 more source

Nociceptor α7nAChR activation blunts neuronal HMGB1 release and attenuates inflammation and nociceptive behavior

Background High Mobility Group Box 1 (HMGB1) is a nuclear protein that upon extracellular release acts as an alarmin to initiate and amplify inflammation.
Huan Yang, Tyler D. Hepler, Ulf Andersson, Aisling Tynan, Serena Petruzzelli, Timothy S. Morgan, Michael Brines, Okito Hashimoto, Saher Chaudhry, Sangeeta S. Chavan, Kevin J. Tracey   +10 more
core   +1 more source

Aβ_1-42-mediated astrocytic activation is α7nAChR mediated.

, 2013
A. Fluorescence ratio image of CA1 loaded with Fura-2AM indicating location of monitored astrocytes. Four astrocytes are circled, and ratio traces over time for these astrocytes are plotted to the right in the presence of Aβ1-42, and the α7nAChR ...
Neela Krushna Codadu (490870), Pandey Pratik (490872), David Andrew Nagel (490873), Alia Awni (490871), H. Rheinallt Parri (324046), Kelly Tennyson Dineley (490875), Tiina Maria Pirttimaki (490869), Eric James Hill (490874)   +7 more
core   +1 more source

Issue Information

Animal Models and Experimental Medicine, Volume 9, Issue 9, Page 1699-1700, September 2026.
wiley   +1 more source

Activation of the α7nAChR by GTS-21 mitigates septic tubular cell injury and modulates macrophage infiltration [PDF]

The most common and serious complication among hospitalized and critically ill patients is sepsis-associated acute kidney damage (S-AKI), which raises the risk of comorbidities and is linked to a high mortality rate. Cholinergic anti-inflammatory pathway
Nakamura, Yasuna, Yang, Aobing, Matsuo, Sayumi, Umene, Ryusuke, Wu, Chia-Hsien, Inoue, Tsuyoshi   +5 more
core   +2 more sources

Anisodamine ameliorates crystalline silica-exposed pulmonary inflammation and fibrosis via the α7nAChR/JAK2/STAT3 signaling pathway

Silicosis is a systemic disease marked by diffuse pulmonary fibrosis resulting from prolonged inhalation of crystalline silica (CS) dust. This study aimed to examine the effects of anisodamine (ANI) on pulmonary inflammation and fibrosis in silicosis, as
Yangyang Wei, Hong Kang, Meng Liu, Xiaorui Ding, Hui Liu, Juan Wu, Puhua Xing, Xiaomei Kong   +7 more
core   +1 more source

Left T7 paravertebral nerve blockade activate the α7nAChR-Dependent CAP in patients undergoing thoracoscopic lobectomy: a prospective controlled study

Objective This study aimed to observe the impact of Tthoracic paravertebral nerve blockade(TPVB) at left T7 level on the α7nAChR-dependent cholinergic anti-inflammatory pathway in patients undergoing thoracoscopic lobectomy.
Zhang Ruijiao, Wu Shiyin, Qu Liangchao, Fang Xingjun, Yuan Peihua, Cheng Liqin, Peng Qinghua   +6 more
core   +1 more source

Image_3_Short-Term High-Fat Diet Consumption Reduces Hypothalamic Expression of the Nicotinic Acetylcholine Receptor α7 Subunit (α7nAChR) and Affects the Anti-inflammatory Response in a Mouse Model of Sepsis.TIFF

, 2019
Sepsis is one of the leading causes of death in hospitalized patients and the chronic and low-grade inflammation observed in obesity seems to worsen susceptibility and morbidity of infections.
Leticia Foglia Santucci (6496106), Anelise Cristina Parras Souza (6496094), Camila Libardi Amaral (6496100), Simone Ferreira Lemes (6496103), Camilla Mendes Souza (6496097), Marciane Milanski (571280), Adriana Souza Torsoni (2901056), Marcio Alberto Torsoni (6496109)   +7 more
core   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Image_2_Short-Term High-Fat Diet Consumption Reduces Hypothalamic Expression of the Nicotinic Acetylcholine Receptor α7 Subunit (α7nAChR) and Affects the Anti-inflammatory Response in a Mouse Model of Sepsis.TIFF

, 2019
Sepsis is one of the leading causes of death in hospitalized patients and the chronic and low-grade inflammation observed in obesity seems to worsen susceptibility and morbidity of infections.
Leticia Foglia Santucci (6496106), Anelise Cristina Parras Souza (6496094), Camila Libardi Amaral (6496100), Simone Ferreira Lemes (6496103), Camilla Mendes Souza (6496097), Marciane Milanski (571280), Adriana Souza Torsoni (2901056), Marcio Alberto Torsoni (6496109)   +7 more
core   +1 more source