Results 71 to 80 of about 3,518 (150)

α7nAChR activation in AT2 cells promotes alveolar regeneration through WNT7B signaling in acute lung injury

JCI Insight, 2023
Reducing inflammatory damage and improving alveolar epithelium regeneration are two key approaches to promoting lung repair in acute lung injury/acute respiratory distress syndrome (ALI/ARDS).
Xiaoyan Chen, Cuiping Zhang, Tianchang Wei, Jie Chen, Ting Pan, Miao Li, Lu Wang, Juan Song, Cuicui Chen, Yan Zhang, Yuanlin Song, Xiao Su   +11 more
doaj   +1 more source

Mechanism of Inflammation Regulation of α7nAChR in Spleen and Spinal Dorsal Horn of Mice with Paclitaxel-induced Neuropathic Pain by Electroacupuncture on Zusanli Acupoint

, 2022
ObjectiveTo investigate the effect of electroacupuncture on Zusanli acupoint on the inflammatory changes of α7 nicotinic acetylcholine receptor (α7nAChR) in spleen and spinal dorsal horn of mice with paclitaxel-induced neuropathic pain (PINP) .MethodsA ...
YU Xiangmei, PANG Lina, WANG Zhifu, CHEN Xiaomei, LAN Yanyan   +4 more
core   +1 more source

Stimulation of alpha 7 nicotinic acetylcholine receptor (α7nAChR) inhibits atherosclerosis via immunomodulatory effects on myeloid cells

, 2019
Alpha 7 nicotinic acetylcholine receptor (α7nAChR) stimulation can regulate acute inflammation, and lack of α7nAChR accelerates atherosclerosis in mice.
Gutiérrez, Saray,, Nilsson, Holger,, Wang, Yixin, Panagaki, Dimitra,, Gan, Li-Ming,, Yang, Li Jin,, Engevall, Kajsa,, Mjörnstedt, Filip,, Michaëlsson, Erik, Ulleryd, Marcus A,, Johansson, Maria E,   +10 more
core   +1 more source

Table_4_Sinomenine Hydrochloride Ameliorates Fish Foodborne Enteritis via α7nAchR-Mediated Anti-Inflammatory Effect Whilst Altering Microbiota Composition.xlsx

, 2021
Foodborne intestinal inflammation is a major health and welfare issue in aquaculture. To prevent enteritis, various additives have been incorporated into the fish diet.
Xuyang Zhao (1951429), Yuhang Liu (507131), Junwei Shan (11074668), Ming Li (91180), Weidong Ye (5005601), Jiayuan Xie (11744387), Xiao-Qin Xia (146389), You Duan (8733021), Yingyin Cheng (290420), Bruno Hamish Unger (11744390), Wanting Zhang (8733018), Nan Wu (200090)   +11 more
core   +1 more source

Note for Male Smokers: The Healthy Eating Index Associated With the Risk of Subclinical Myocardial Injury

Clinical Cardiology, Volume 49, Issue 5, May 2026.
Flow chart of the study population. ABSTRACT Objectives To investigate the associations of the healthy eating index (HEI) and subclinical myocardial injury (SCMI) in different smoking statuses (current smokers, former smokers, and never smokers) based on the National Health and Nutrition Examination Survey (NHANES) III.
Zhi‐jin Li, Bin‐gui Li
wiley   +1 more source

Binding affinities of PMP-311 and PMP-072 for α7nAChR, α4β2 nAChR and α1β1 nAChR.

, 2015
Binding affinities of PMP-311 and PMP-072 for α7nAChR, α4β2 nAChR and α1β1 nAChR.
Gregory J. LaRosa (685996), Jessica Koepke (685991), Daniel Elbaum (685995), Paul P. Tak (23064), Frieda A. Koopman (613157), Roger Clark (685993), Margriet J. Vervoordeldonk (613162), Diana Lamppu (685994), Marjolein A. van Maanen (685989), Lisette Bevaart (685992), Roger L. Papke (685990)   +10 more
core   +1 more source

DataSheet_1_Sinomenine Hydrochloride Ameliorates Fish Foodborne Enteritis via α7nAchR-Mediated Anti-Inflammatory Effect Whilst Altering Microbiota Composition.pdf

, 2021
Foodborne intestinal inflammation is a major health and welfare issue in aquaculture. To prevent enteritis, various additives have been incorporated into the fish diet.
Xuyang Zhao (1951429), Yuhang Liu (507131), Junwei Shan (11074668), Ming Li (91180), Weidong Ye (5005601), Jiayuan Xie (11744387), Xiao-Qin Xia (146389), You Duan (8733021), Yingyin Cheng (290420), Bruno Hamish Unger (11744390), Wanting Zhang (8733018), Nan Wu (200090)   +11 more
core   +1 more source

Nutritional Interventions and Acupuncture‐Based Strategies for Exercise‐Induced Fatigue and Recovery: Mechanisms and Integrative Perspectives

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Excessive exercise induces exercise‐induced fatigue through multiple interconnected mechanisms, including energy shortage and metabolite accumulation, oxidative stress and inflammation, mitochondrial dysfunction, and neuroendocrine strain. Integrative management strategies include nutrition‐based approaches and acupuncture‐based interventions ...
Yaqin Yang, Yao Yao, Weiyu Lu, Jiazhou Li, Lijuan Zou, Huashan Pan   +5 more
wiley   +1 more source

Blockade of the α7nAChR reverses DEX-induced downregulation of HMGB1 during I/R.

, 2019
To explore the involvement of α7nAChR, methyllycaconitine (MLA, α7nAChR antagonist) was administered. HMGB1 protein levels in the left ventricles were measured using Western blot (a) and HMGB1 mRNA levels were assessed by q-RT-PCR (b).
Juan Zhang (48597), Ke Peng (2220973), Huayue Liu (7041752), Fan Xia (219575), Haifeng Zhao (607312), Xiaowen Meng (7041755), Chen Chen (6544), Fuhai Ji (469046)   +7 more
core   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, Volume 183, Issue 10, Page 2177-2196, May 2026.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source