Results 61 to 70 of about 3,518 (150)

Research Progress on Alleviating Inflammatory Responses by Regulating Macrophage Polarization Using Medicinal and Edible Homologous Traditional Chinese Medicines

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
This review summarizes that medicinal and edible homologous TCMs—such as Mongolian milkvetch root, common turmeric rhizome, and Angelica—alleviate chronic inflammatory diseases (IBD, RA, and AS) by inhibiting M1 and promoting M2 macrophage polarization, providing a theoretical basis for inflammation therapy and daily dietary intervention.
Cheng Zhang   +15 more
wiley   +1 more source

Vagotomy Affects the Development of Oral Tolerance and Increases Susceptibility to Develop Colitis Independently of α-7 Nicotinic Receptor

open access: yesMolecular Medicine, 2016
Vagotomy (VGX) increases the susceptibility to develop colitis suggesting a crucial role for the cholinergic anti-inflammatory pathway in the regulation of the immune responses.
Martina Di Giovangiulio   +8 more
doaj   +1 more source

Physiologic Functions and Therapeutic Applications of α7 Nicotinic Acetylcholine Receptor in Brain Disorders

open access: yesPharmaceutics, 2022
Accumulating data suggest that α7 nicotinic acetylcholine receptors (α7nAChRs) are an important therapeutic target for the treatment of Alzheimer’s disease (AD) and schizophrenia.
Chien-Hsing Lee, Shih-Ya Hung
doaj   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 18, Page 5458-5475, September 2026.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle   +12 more
wiley   +1 more source

The Role of the Autonomic Nervous System in Atherosclerosis - Targeting the Cholinergic Anti-inflammatory Pathway in Humans and Mice [PDF]

open access: yes, 2014
The autonomic nervous system (ANS) has been implicated in numerous atherosclerosis-induced cardiovascular disease, such as myocardial infarction and stroke.
Bernberg, Evelina,   +5 more
core   +1 more source

Table_2_Sinomenine Hydrochloride Ameliorates Fish Foodborne Enteritis via α7nAchR-Mediated Anti-Inflammatory Effect Whilst Altering Microbiota Composition.xlsx

open access: yes, 2021
Foodborne intestinal inflammation is a major health and welfare issue in aquaculture. To prevent enteritis, various additives have been incorporated into the fish diet.
Xuyang Zhao (1951429)   +11 more
core   +1 more source

Table_3_Sinomenine Hydrochloride Ameliorates Fish Foodborne Enteritis via α7nAchR-Mediated Anti-Inflammatory Effect Whilst Altering Microbiota Composition.xlsx

open access: yes, 2021
Foodborne intestinal inflammation is a major health and welfare issue in aquaculture. To prevent enteritis, various additives have been incorporated into the fish diet.
Xuyang Zhao (1951429)   +11 more
core   +1 more source

Activation of α7 Nicotinic Acetylcholine Receptor Protects Against 1-Methyl-4-Phenylpyridinium-Induced Astroglial Apoptosis

open access: yesFrontiers in Cellular Neuroscience, 2019
Astrocytes, as the largest population of glial subtype, play crucial roles in normal brain function and pathological conditions, such as Parkinson’s disease (PD).
Ye Hua   +5 more
doaj   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

open access: yesCell Proliferation, Volume 59, Issue 8, August 2026.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao   +7 more
wiley   +1 more source

Effects of VAChT reduction and α7nAChR stimulation by PNU-282987 in lung inflammation in a model of chronic allergic airway inflammation

open access: yes, 2020
The cholinergic anti-inflammatory pathway has been shown to regulate lung inflammation and cytokine release in acute models of inflammation, mainly via α7 nicotinic receptor (α7nAChR).
Tiberio, Iolanda de Fátima Lopes Calvo   +13 more
core   +1 more source

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