Results 51 to 60 of about 3,518 (150)

NRG increases α7nAChR expression in microglia and macrophages.

, 2013
Microglia (BV-2) and macrophage (RAW) cell cultures were treated overnight with NRG (N) or left untreated (C). LPS (L) was added to activate cells four hours prior to extraction.
Christian Jacobson (376403), Michelle Nash (158363), Malwina Mencel (439471)   +2 more
core   +1 more source

Vagal-α7nAChR signaling promotes lung stem cells regeneration via fibroblast growth factor 10 during lung injury repair

Stem Cell Research & Therapy, 2020
Background Proliferation and transdifferentiation of lung stem cells (LSCs) could promote lung injury repair. The distal airways of the lung are innervated by the vagus nerve.
Xiaoyan Chen, Caiqi Zhao, Cuiping Zhang, Qingmei Li, Jie Chen, Lianping Cheng, Jian Zhou, Xiao Su, Yuanlin Song   +8 more
doaj   +1 more source

α7 Nicotinic Acetylcholine Receptor Signaling Modulates Ovine Fetal Brain Astrocytes Transcriptome in Response to Endotoxin

Frontiers in Immunology, 2019
Neuroinflammation in utero may result in lifelong neurological disabilities. Astrocytes play a pivotal role in this process, but the mechanisms are poorly understood.
Mingju Cao, James W. MacDonald, Hai L. Liu, Molly Weaver, Marina Cortes, Lucien D. Durosier, Patrick Burns, Gilles Fecteau, André Desrochers, Jay Schulkin, Marta C. Antonelli, Raphael A. Bernier, Michael Dorschner, Theo K. Bammler, Martin G. Frasch, Martin G. Frasch, Martin G. Frasch, Martin G. Frasch   +17 more
doaj   +1 more source

Acupuncture for Poststroke Dysphagia: An NTS‐Centered Hypothesis‐Generating Framework Linking the Brainstem Swallowing Network, Neuroimmune Regulation, and Vagal Anti‐Inflammatory Signaling

Brain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Background Poststroke dysphagia (PSD) may reflect not only focal motor pathway injury but also instability of the brainstem swallowing network under neuroimmune, glial, and vascular microenvironmental stress. Methods This mechanism‐oriented narrative review synthesized evidence on swallowing central pattern generator (CPG) organization ...
Wei Li, Lebin Liu, Yingying Tu, Chongjiu Gong, Xiao Ran, Jiuguo Pei   +5 more
wiley   +1 more source

Activation of α7 nicotinic acetylcholine receptor decreases on-site mortality in crush syndrome through insulin signaling-Na/K-ATPase pathway

Frontiers in Pharmacology, 2016
On-site mortality in crush syndrome remains high due to lack of effective drugs based on definite diagnosis. Anisodamine is widely used in China for treatment of shock, and activation of α7 nicotinic acetylcholine receptor (α7nAChR) mediates such ...
Bo-Shi eFan, En-Hui eZhang, En-Hui eZhang, Miao eWu, Jin-Min eGuo, Ding-Feng eSu, Liu eXia, Jian-Guang eYu   +7 more
doaj   +1 more source

Microglia and neuroinflammation: An in‐depth analysis from functional diversity to disease mechanisms

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
1. Microglial functions arise from dynamic, context‐dependent programs rather than fixed M1/M2 phenotypes. 2. Inflammatory, interferon‐responsive, phagocytic/lipid‐metabolic and repair‐associated programs coexist across disease stages and brain regions. 3.
Jie Chen, Wangzheqi Zhang, Lizhou Song, Yan Liao, Haoling Zhang, Yiyang Xia, Derong Cui   +6 more
wiley   +1 more source

Immunohistochemical expression of CD11b, RECA-1 and α7nAChR in the lung. A)

, 2013
Lungs harvested 6 hours after heat stress were stained for CD11b (green), RECA-1 (red), and α7nAChR (blue). The arrows indicate CD11b-positive cells expressing α7nAChR. Bars represent 20 µm, original magnification ×1200.
Junya Shimazaki (284145), Yasuyuki Kuwagata (284149), Takashi Muroya (284139), Yukio Imamura (284137), Junichiro Nakagawa (284143), Naoya Matsumoto (284135), Tomoki Yamada (284141), Hiroshi Ogura (284147), Kazuma Yamakawa (284134), Takeshi Shimazu (284151)   +9 more
core   +1 more source

Activation of Cholinergic Anti-Inflammatory Pathway Ameliorates Cerebral and Cardiac Dysfunction After Intracerebral Hemorrhage Through Autophagy

Frontiers in Immunology, 2022
BackgroundIntracerebral hemorrhage (ICH) is the devastating subtype of stroke with cardiovascular complications, resulting in high rates of mortality and morbidity with the release of inflammatory factors.
Yue Su, Wei Zhang, Ruoxi Zhang, Quan Yuan, Ruixia Wu, Xiaoxuan Liu, Jimusi Wuri, Ran Li, Tao Yan   +8 more
doaj   +1 more source

Migraine: Epidemiology, Risk Factors, Pathophysiology, and Treatment

MedComm, Volume 7, Issue 9, September 2026.
Migraine is a highly prevalent, female‐predominant, and disabling brain disorder shaped by genetic susceptibility, hormonal influences, modifiable attack factors, and comorbidity‐related progression. This review integrates current evidence on migraine epidemiology, phase‐specific neurovascular and neuroglial mechanisms, including CGRP signaling and ...
Weiwei Lu, Yuan Zhang, Chen Shi, Yu Tao, Shaoxin Li, Yufang Sun, Fuhai Ji, Dongsheng Jiang, Terrance P. Snutch, Jin Tao   +9 more
wiley   +1 more source

Table_1_Sinomenine Hydrochloride Ameliorates Fish Foodborne Enteritis via α7nAchR-Mediated Anti-Inflammatory Effect Whilst Altering Microbiota Composition.xlsx

, 2021
Foodborne intestinal inflammation is a major health and welfare issue in aquaculture. To prevent enteritis, various additives have been incorporated into the fish diet.
Xuyang Zhao (1951429), Yuhang Liu (507131), Junwei Shan (11074668), Ming Li (91180), Weidong Ye (5005601), Jiayuan Xie (11744387), Xiao-Qin Xia (146389), You Duan (8733021), Yingyin Cheng (290420), Bruno Hamish Unger (11744390), Wanting Zhang (8733018), Nan Wu (200090)   +11 more
core   +1 more source