Cholinergic anti-inflammatory pathway and COVID-19 [PDF]
BioImpacts, 2022 The cholinergic anti-inflammatory pathway (CAP) first described by Wang et al, 2003 has contemporary interest arising from the COVID-19 pandemic. While tobacco smoking has been considered an aggravating factor in the severity of COVID-19 infections, it ...
Danial Mehranfard, Robert C. Speth
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Pyridostigmine bromide elicits progressive and chronic impairments in the cholinergic anti-inflammatory pathway in the prefrontal cortex and hippocampus of male rats [PDF]
Neurobiology of Stress, 2022 Gulf War Illness (GWI) is a multi-symptom illness that continues to affect over 250,000 American Gulf War veterans. The causes of GWI remain equivocal; however, prophylactic use of the acetylcholinesterase inhibitor pyridostigmine bromide (PB), and the ...
H.E. Burzynski +8 more
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Role of Cholinergic Anti-Inflammatory Pathway in Protecting Sepsis-Induced Acute Lung Injury through Regulation of the Conventional Dendritic Cells [PDF]
Mediators of Inflammation, 2022 Background. The cholinergic anti-inflammatory pathway connects the immune response system and the nervous system via the vagus nerve. The key regulatory receptor is the α7-subtype of the nicotinic acetylcholine receptor (α7nAChR).
Ruiting Li +11 more
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The cholinergic anti-inflammatory pathway inhibits inflammation without lymphocyte relay [PDF]
Frontiers in Neuroscience, 2023 The magnitude of innate inflammatory immune responses is dependent on interactions between peripheral neural and immune cells. In particular, a cholinergic anti-inflammatory pathway (CAP) has been identified in the spleen whereby noradrenaline (NA ...
Thomas Simon +16 more
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Pharmacological and Electroceutical Targeting of the Cholinergic Anti-Inflammatory Pathway in Autoimmune Diseases [PDF]
Pharmaceuticals, 2023 Continuous dialogue between the immune system and the brain plays a key homeostatic role in various immune responses to environmental cues. Several functions are under the control of the vagus nerve-based inflammatory reflex, a physiological mechanism ...
Moncef Zouali
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The brain-liver cholinergic anti-inflammatory pathway and viral infections [PDF]
Bioelectronic Medicine, 2023 Efferent cholinergic signaling is a critical and targetable source of immunoregulation. The vagus nerve (VN) is the primary source of cholinergic signaling in the body, and partially innervates hepatic functionality through the liver-brain axis.
Samuel Martínez-Meza +4 more
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The potential for traditional Chinese therapy in treating sleep disorders caused by COVID-19 through the cholinergic anti-inflammatory pathway [PDF]
Frontiers in Pharmacology, 2022 Since the outbreak of Coronavirus disease (COVID-19) in 2019, it has spread rapidly across the globe. Sleep disorders caused by COVID-19 have become a major concern for COVID-19 patients and recovered patients.
Xiaoxia Xie +14 more
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The cholinergic anti-inflammatory pathway alleviates acute lung injury [PDF]
Molecular Medicine, 2020 The ubiquiotous nuclear protein HMGB1 is extracellularly released by dying cells or activated innate immunity cells to promote inflammation. Extracellular HMGB1 plays a prominent role in the pathogenesis of acute lung injury of infectious as well as ...
Ulf Andersson
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Cholinergic Anti-Inflammatory Pathway and the Liver [PDF]
Advanced Pharmaceutical Bulletin, 2017 The hepatic vagus branches innervate the liver and serve an important role in liver-brain connection. It appears that brain modulates inflammatory responses by activation of vagal efferent fibers.
Khalil Hajiasgharzadeh, Behzad Baradaran
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundWith chronic ischemia after myocardial infarction, the resulting scar tissue result in electrical and structural remodeling vulnerable to an arrhythmogenic substrate.
Shu‐Jie Wu +8 more
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